Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…TEA-sensitive currents were specifically decreased in PV interneurons from mice that received cuprizone treatment compared to control mice (<i>group x voltage two-way repeated measures: n = 10,14 cells from 5 mice per group: F(13,286) = 5.082, p < 0.0001</i>). …”

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…In pursuit of a more potent and selective CBP inhibitor, we used structure-based design. …”

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …”

Time allocation may not decrease with price for a non-linear microscopic utility of leisure. by Ritwik K. Niyogi (427932)

“…Consequently, <i>TA</i> no longer decreases but may even increase with price (A, lower panel). …”

CCN3 protein decreases β-cell proliferation. by Renée Paradis (326111)

Effects of siRNA TMPRSS2-ERG III and IV on cell death pathways. by Giorgia Urbinati (554921)

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis by Raj Vuppalanchi (458660)

“…In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis.…”

Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study by Sérgio Aparecido Cleto (3143949)

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis by Chenlu Zhang (508309)

“…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …”

Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis by Chenlu Zhang (508309)

“…Evidence showed that intestinal FXR antagonism exhibited remarkable metabolic improvements in mice. Herein, we developed a series of betulinic acid derivatives as potent intestinal FXR antagonists, and <b>F6</b> was identified as the most potent one with an IC₅₀ at 2.1 μM. …”

A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population by Victoria L. Herrera (383897)

“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”

Data_Sheet_1_Perceptual Priming Can Increase or Decrease With Aging.PDF by Kalathupiriyan A. Zhivago (9659504)

“…To measure implicit perceptual memory, we used a classic perceptual priming paradigm. Participants had to report the shape of a visual search pop-out target whose color or position was varied randomly across trials. …”

<i>Mycobacterium tuberculosis</i> thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity - Fig 2 by Apurba Sarkar (8399571)

Inhibition of RIP1 or MLKL decreases morbidity and mortality during <i>S</i>. <i>marcescens</i> hemorrhagic pneumonia. by Norberto González-Juarbe (836747)

Immunohistochemical detection of myeloperoxidase, CD3 and CD45 in the pancreas during experimental AP. by Sebastian Weis (161447)

Immunohistochemical detection and quantification of myeloperoxidase, CD3 and CD45 positive cells in the lung during experimental AP. by Sebastian Weis (161447)

The U937 cell line was seeded at 2 x 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

The U937 cell line was seeded at 1 x 10⁵ cells per well. by Janani Madhuravasal Krishnan (19736002)

Heart specific RNase Z variants show a mild decrease in longevity and locomotor response. by Ekaterina Migunova (15909887)