Image 3_The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells.tif by Maressa Fernandes Bonfim (6700379)

“…Here we show that the N6-methyladenosine (m6A) RNA epigenetic modification machinery regulates CVB1 amplification in the human beta cells. Using small interfering RNA (siRNA) targeting m6A writers and erasers, we observed that downregulation of m6A writers increases CVB1 amplification, while the downregulation of m6A erasers decreases it. …”

Image 1_The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells.tif by Maressa Fernandes Bonfim (6700379)

“…Here we show that the N6-methyladenosine (m6A) RNA epigenetic modification machinery regulates CVB1 amplification in the human beta cells. Using small interfering RNA (siRNA) targeting m6A writers and erasers, we observed that downregulation of m6A writers increases CVB1 amplification, while the downregulation of m6A erasers decreases it. …”

Image 2_Anticancer activity of RM-3-22: a TAZQ-based hydroxamic acid derivative targeting NSCLC in vitro and in vivo.jpeg by Essha Chatterjee (9400908)

“…We evaluated its anticancer activity in non-small cell lung cancer (NSCLC), using A549 adenocarcinoma cells as the primary model.…”

Image 1_Effect of hypoxia-induced mIL15 expression on expansion and memory progenitor stem-like TILs in vitro.tif by Zhen Sun (269397)

“…Introduction<p>The adoptive cell transfer of tumor-infiltrating lymphocytes (TILs) has proven clinically beneficial in patients with non-small cell lung cancer refractory to checkpoint blockade immunotherapy, which has prompted interest in TIL-adoptive cell transfer. …”

Data Sheet 1_Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols.pdf by Walther Haenseler (21074168)

“…Cilia in hiPSCs, NSCs and neurons were all positive for ARL13B, with a decreasing trend in intensity in more mature neurons. …”

Table 1_Anticancer activity of RM-3-22: a TAZQ-based hydroxamic acid derivative targeting NSCLC in vitro and in vivo.docx by Essha Chatterjee (9400908)

“…We evaluated its anticancer activity in non-small cell lung cancer (NSCLC), using A549 adenocarcinoma cells as the primary model.…”

Image 4_The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells.tif by Maressa Fernandes Bonfim (6700379)

“…Here we show that the N6-methyladenosine (m6A) RNA epigenetic modification machinery regulates CVB1 amplification in the human beta cells. Using small interfering RNA (siRNA) targeting m6A writers and erasers, we observed that downregulation of m6A writers increases CVB1 amplification, while the downregulation of m6A erasers decreases it. …”

Data Sheet 1_Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment.docx by Dalia Ibrahim (14825149)

“…</p>Methods<p>In this study, for the first time, we assessed the therapeutic potential of novel covalent irreversible small molecule TG2 inhibitors in xenograft models of ovarian cancer. …”

Evolution from a single 20-year model simulation of a 5-year cycling strategy with DHA-PPQ used in the first five years, ASAQ in the following five years, AL during years 10-15, an... by Kien Trung Tran (12035464)

Image 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Data Sheet 2_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…SRGN and SNCA were identified as potential targets for heparin and 33 other drugs, respectively. qRT-PCR performed on a small number of myocardial samples supported expression trends of the identified genes, in line with transcriptomic analysis.…”

DataSheet1_Effect of Coptidis Rhizoma on gastrointestinal system before and after processing with wine based on gut microbiota and short chain fatty acids.docx by Rui Tian (635672)

“…CD caused different degree of damage to the gastrointestinal tract, and the effect on the small intestine and colon was more obvious, which increased the expression of NF-κB p65 and elevated the inflammatory factors levels. …”

Data Sheet 5_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…SRGN and SNCA were identified as potential targets for heparin and 33 other drugs, respectively. qRT-PCR performed on a small number of myocardial samples supported expression trends of the identified genes, in line with transcriptomic analysis.…”

Table 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Data Sheet 4_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…SRGN and SNCA were identified as potential targets for heparin and 33 other drugs, respectively. qRT-PCR performed on a small number of myocardial samples supported expression trends of the identified genes, in line with transcriptomic analysis.…”

Table 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Image 2_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.pdf by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”

Data Sheet 1_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…SRGN and SNCA were identified as potential targets for heparin and 33 other drugs, respectively. qRT-PCR performed on a small number of myocardial samples supported expression trends of the identified genes, in line with transcriptomic analysis.…”

Figure 4 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…However, the levels of DX5+ (NKT cells) decreased slightly but significantly in TI (<i>P</i> = 0.017). …”

Data Sheet 1_CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.docx by Kai Sun (140584)

“…Notably, the silencing of CHMP4A markedly decreased the expression levels of the TIM3/LGALS9 immune checkpoint axis in LIHC.…”