-
2101
Image 3_Small-molecule MMRi36 induces apoptosis in p53-mutant lymphomas by targeting MDM2/MDM4/XIAP for degradation.jpg
Published 2024“…Therefore, MMRi36 is a novel prototype small-molecule for targeting MDM2/MDM4/XIAP for degradation and induction of apoptosis in p53-mutant lymphomas.…”
-
2102
Table 1_High-dose ascorbic acid synergizes with anti-PD1 therapy in non-small cell lung cancer in vitro and in vivo models.xlsx
Published 2025“…Introduction<p>Immune checkpoint inhibitors(ICIs) targeting programmed cell death protein 1 (PD1) confer significant survival benefits to patients with non-small cell lung cancer (NSCLC). However, there remains a substantial unmet need to identify therapeutic approaches to overcome resistance and provide benefits to these patients. …”
-
2103
Image 2_Small-molecule MMRi36 induces apoptosis in p53-mutant lymphomas by targeting MDM2/MDM4/XIAP for degradation.jpg
Published 2024“…Therefore, MMRi36 is a novel prototype small-molecule for targeting MDM2/MDM4/XIAP for degradation and induction of apoptosis in p53-mutant lymphomas.…”
-
2104
<b>Small extracellular vesicle-encapsulated miR-146a suppresses neuroretinal pyroptosis through inhibition microglial activation in retinal vein occlusion</b>
Published 2025“…However, its pathogenesis is complex, and recurrence after treatment is common. Small extracellular vesicles (sEVs) and their cargoes have demonstrated great potential in disease diagnosis and treatment. …”
-
2105
-
2106
Table 1_GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway.docx
Published 2025“…Background<p>Brain metastasis (BM) remains a major challenge in non-small cell lung cancer (NSCLC) treatment, with poorly understood mechanisms.…”
-
2107
Data Sheet 1_Plasma IgG and IgM autoantibodies to COPT1 as potential biomarkers for detection of non-small cell lung cancer.pdf
Published 2025“…The purpose of this study is to explore the significance of anti-COPT1 autoantibodies in the clinical diagnosis of non-small cell lung cancer (NSCLC).</p>Methods<p>The expression level of COPT1 in NSCLC and normal tissues was analyzed based on TCGA and the Human Protein Atlas (HPA) database. …”
-
2108
-
2109
Data Sheet 1_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.xlsx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2110
Data Sheet 3_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.xlsx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2111
Data Sheet 5_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.xlsx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2112
Data Sheet 4_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.xlsx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2113
Data Sheet 6_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.docx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2114
Data Sheet 2_Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.xlsx
Published 2025“…Introduction<p>Lung cancer, predominantly non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality worldwide. …”
-
2115
Figure 1 from EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity
Published 2025“…<p>Expression of EML4-ALK V3 increases microtubule stability in mitosis. <b>A,</b> H3122 and H2228 cells were incubated on ice for 15 minutes before being fixed and stained with α-tubulin (red) and CENP-A (green) antibodies. …”
-
2116
Data Sheet 1_Immune checkpoint inhibitors for extensive-stage small-cell lung cancer: a network meta-analysis and cost-effectiveness analysis.docx
Published 2025“…Background<p>Despite the established efficacy of immune checkpoint inhibitors (ICIs) in combination with chemotherapy, with or without anti-angiogenic agents, for extensive-stage small-cell lung cancer (ES-SCLC), a comprehensive comparative assessment of these regimens remains lacking. …”
-
2117
Data Sheet 1_DDR1 as a key prognostic biomarker in non-small cell lung cancer: identification, validation, and potential therapeutic implications.pdf
Published 2025“…Background<p>Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related death, with a limited response to immune checkpoint inhibitors (ICIs). …”
-
2118
Image 2_Lung cancer-associated fibroblasts-mediated collagen deposition drives mediastinal lymph node metastasis in non-small cell lung cancer.jpeg
Published 2025“…Introduction<p>Metastasis to mediastinal lymph nodes signifies an advanced stage of non-small cell lung cancer (NSCLC) and presents significant clinical challenges. …”
-
2119
Image 3_Lung cancer-associated fibroblasts-mediated collagen deposition drives mediastinal lymph node metastasis in non-small cell lung cancer.jpeg
Published 2025“…Introduction<p>Metastasis to mediastinal lymph nodes signifies an advanced stage of non-small cell lung cancer (NSCLC) and presents significant clinical challenges. …”
-
2120
Image 1_Lung cancer-associated fibroblasts-mediated collagen deposition drives mediastinal lymph node metastasis in non-small cell lung cancer.jpeg
Published 2025“…Introduction<p>Metastasis to mediastinal lymph nodes signifies an advanced stage of non-small cell lung cancer (NSCLC) and presents significant clinical challenges. …”