Data Sheet 1_Global, regional and national burden of pancreatic cancer and its attributable risk factors from 2019 to 2021, with projection to 2044.docx by Xiao Li (107004)

“…Background<p>To estimate the global burden of pancreatic cancer in 2019 and 2021 including incidence, mortality, and disability-adjusted-life-years (DALYs).…”

DataSheet3_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…</p>Objective<p>We developed and validated a tissue deconvolution framework using a reference dataset derived from single-nucleus RNA sequencing (snRNA-seq) of normal pituitary tissue, aimed at estimating cellular composition in PitNETs from bulk RNA-seq data and characterizing the tumor microenvironment (TME).…”

Adjacency by Yulu Dai (21387734)

“…In this approach, the mobility of EVs is prioritized before decreasing the impact of EVs operation on normal traffic. …”

Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx by Anqi Wu (3413069)

“…In the stomach, along with the diminishing of AKR1B10 expression, CD68+ macrophage increased and CD19+ B cell decreased in gastric cancer.</p>Discussion<p>These data indicates that AKR1B10 may be an important factor in the development and progression and a potential therapeutic target for multiple cancers, but plays as a protector in the gastric tissues.…”

Parameters and values used in experiments. by Yulu Dai (21387734)

“…In this approach, the mobility of EVs is prioritized before decreasing the impact of EVs operation on normal traffic. …”

Supplementary file 1_Dissecting the causal association of diet with thyroid cancer: a systematic review with meta-analysis and mendelian randomization analysis..docx by Chao Kang (487155)

“…</p>Conclusion<p>This comprehensive study investigated the relationships between dietary factors and thyroid cancer risk, synthesizing findings from a meta-analysis of observational studies and MR analysis to estimate causal associations. Consistently, both the meta-analysis and MR analysis revealed that consumption of certain types of fish may be linked to a decreased risk of thyroid cancer.…”

DataSheet5_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

DataSheet2_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Image 1_Dissecting the causal association of diet with thyroid cancer: a systematic review with meta-analysis and mendelian randomization analysis..pdf by Chao Kang (487155)

“…</p>Conclusion<p>This comprehensive study investigated the relationships between dietary factors and thyroid cancer risk, synthesizing findings from a meta-analysis of observational studies and MR analysis to estimate causal associations. Consistently, both the meta-analysis and MR analysis revealed that consumption of certain types of fish may be linked to a decreased risk of thyroid cancer.…”

Supplementary Material for: Age-Period-Cohort Analysis of Mortality from Ischemic Stroke Attributable to High Systolic Blood Pressure: Trends and 2030 Projections for Turkey and Eu... by figshare admin karger (2628495)

“…Conclusion: Although HSBP-related IS mortality generally decreased across Europe, substantial regional and sex-based disparities persisted. …”

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…Cochran Q test was used to evaluate SNP estimate heterogeneity. MR-Egger and MR-PRESSO methods were utilized to detect horizontal pleiotropy.…”

Sensitivity analysis for acute fatigue subscale. by Rong Pi (21743379)

“…The restricted maximum-likelihood estimator was utilized to calculate the heterogeneity variance τ². …”

Factors related to nurses’ occupational fatigue. by Rong Pi (21743379)

“…The restricted maximum-likelihood estimator was utilized to calculate the heterogeneity variance τ². …”

Sensitivity analysis for inter-shift subscale. by Rong Pi (21743379)

“…The restricted maximum-likelihood estimator was utilized to calculate the heterogeneity variance τ². …”

Image 9_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…</p>Results<p>Prior to disk puncture paw withdrawal thresholds were 3.44 ± 0.51 g before surgery and were reduced to 0.54 ± 0.38 g at day 7 without a difference by sex; however, sex-specific responses were evident in other behavioral outcomes. EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Image 8_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…</p>Results<p>Prior to disk puncture paw withdrawal thresholds were 3.44 ± 0.51 g before surgery and were reduced to 0.54 ± 0.38 g at day 7 without a difference by sex; however, sex-specific responses were evident in other behavioral outcomes. EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Image 7_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…</p>Results<p>Prior to disk puncture paw withdrawal thresholds were 3.44 ± 0.51 g before surgery and were reduced to 0.54 ± 0.38 g at day 7 without a difference by sex; however, sex-specific responses were evident in other behavioral outcomes. EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 11_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…</p>Results<p>Prior to disk puncture paw withdrawal thresholds were 3.44 ± 0.51 g before surgery and were reduced to 0.54 ± 0.38 g at day 7 without a difference by sex; however, sex-specific responses were evident in other behavioral outcomes. EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data_Sheet_1_Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study int... by Giuseppe Maglietta (12992976)

“…Level change for Mental Disorders significantly decreased during school closure (HRR 0.50, 95%CI 0.30–0.82) but increased during mitigation measures by 28% (HRR 1.28, 95%CI 0.98–1.69).…”