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Chronic CuO Nanoparticles Exposure Enhances Bacterial Antibiotic Sensitivity and Attenuates Bacterial Pathogenicity
Published 2025“…In this study, we demonstrate that Gram-negative bacteria (Escherichia coli ATCC 25922, ATCC 35128, BAA 2452, and Pseudomonas aeruginosa CICC 21636) exposed to CuO NPs for 180 generations developed resistance to the nanoparticle and exhibited increased susceptibility to multiple antibiotics, with inhibition rates rising by up to 29.4% at MIC<sub>50</sub>. …”
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Disruption of Surface Bacterial Communities by Indoor Ambient Sulfur Dioxide
Published 2025Subjects: -
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<i>Mesorhizobium huakuii</i> 7653 R regulates the endophytic bacterial communities and disease resistance pathways to promote clubroot resistance in <i>Brassica napus</i>
Published 2025“…We characterized the composition and structure of the endophytic microbiota using bacterial 16S sequencing, and showed that treatment with <i>M. huakuii</i> 7653 R shaped the structure of endophytic bacterial communities. …”
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Increased copy number couples the evolution of plasmid horizontal transmission and plasmid-encoded antibiotic resistance (dataset)
Published 2025“…Conjugative plasmids are mobile elements which spread horizontally between bacterial hosts, and often confer adaptive phenotypes, including antimicrobial resistance (AMR). …”
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Data Sheet 1_Based on quorum sensing: reverse effect of traditional Chinese medicine on bacterial drug resistance mechanism.pdf
Published 2025“…Pathogenic bacteria utilize six principal resistance mechanisms: (1) Enzymatic degradation of antibiotics via the production of inactivating enzymes; (2) Inactivation of antibiotics by changing the drug targets; (3) Reduction of antibiotics entry by decreasing bacterial permeability; (4) Enhanced antibiotics efflux through overexpression of efflux pumps; (5) Acquisition of antibiotics resistance via genetic mutations; (6) Development of antibiotics resistance through formation of microbial biofilms. …”
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Hybrid Antibiotics Targeting the Bacterial Ribosome
Published 2025“…Antimicrobial resistance remains a formidable challenge to modern medicine, with bacterial resistance mechanisms increasingly eroding the utility of clinically important antibiotics. …”
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Hybrid Antibiotics Targeting the Bacterial Ribosome
Published 2025“…Antimicrobial resistance remains a formidable challenge to modern medicine, with bacterial resistance mechanisms increasingly eroding the utility of clinically important antibiotics. …”