Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug–Drug Interactions <i>in Vitro</i> and in Patient Samples Autor Marie-Noëlle Paludetto (5683055)

“…However, the recent discovery of new reactive metabolites (RM) with aldehyde structures during pazopanib and sunitinib metabolism offers new perspectives for investigating their involvement in the toxicity of these two TKI. These hard electrophiles have a high reactivity potential toward proteins and are thought to be responsible for cytochrome P450 inactivation, drug–drug interactions (DDI), and liver toxicity. …”

Soft or Hard? Investigating the Deformation Mechanisms of Au–Pd and Pd Nanocubes under Compression: An Experimental and Molecular Dynamics Study Autor Juan A. de la Rosa Abad (11649462)

Soft or Hard? Investigating the Deformation Mechanisms of Au–Pd and Pd Nanocubes under Compression: An Experimental and Molecular Dynamics Study Autor Juan A. de la Rosa Abad (11649462)

Soft or Hard? Investigating the Deformation Mechanisms of Au–Pd and Pd Nanocubes under Compression: An Experimental and Molecular Dynamics Study Autor Juan A. de la Rosa Abad (11649462)

Soft or Hard? Investigating the Deformation Mechanisms of Au–Pd and Pd Nanocubes under Compression: An Experimental and Molecular Dynamics Study Autor Juan A. de la Rosa Abad (11649462)

Soft or Hard? Investigating the Deformation Mechanisms of Au–Pd and Pd Nanocubes under Compression: An Experimental and Molecular Dynamics Study Autor Juan A. de la Rosa Abad (11649462)

Image_1_An Iron Transporter Is Involved in Iron Homeostasis, Energy Metabolism, Oxidative Stress, and Metacyclogenesis in Trypanosoma cruzi.tif Autor Claudia F. Dick (9932102)

“…Fe is an essential cofactor in many metabolic pathways. Fe is also harmful due to catalyzing the formation of reactive O₂ species; for this reason, all living systems develop mechanisms to control the uptake, metabolism, and storage of Fe. …”

Image_2_Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments.TIF Autor María Lamprecht-Grandío (122658)

“…The present study aimed to identify new genes involved in UV radiation resistance from these microorganisms, many of which cannot be cultured in the laboratory. …”

Image_1_Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments.TIF Autor María Lamprecht-Grandío (122658)

“…The present study aimed to identify new genes involved in UV radiation resistance from these microorganisms, many of which cannot be cultured in the laboratory. …”

Table_1_Novel Genes Involved in Resistance to Both Ultraviolet Radiation and Perchlorate From the Metagenomes of Hypersaline Environments.pdf Autor María Lamprecht-Grandío (122658)

“…The present study aimed to identify new genes involved in UV radiation resistance from these microorganisms, many of which cannot be cultured in the laboratory. …”

The maximum time [h] to reach the equilibrium concentration for caprylate and NAT removal and adsorption capacity [mg/g] for caprylate and NAT of each adsorbent in the batch tests. Autor Stephan Harm (4794978)

Correlation of cigarette butts counted and removed in Round 1 with cigarette butts counted in Round 2. Autor Georg E. Matt (2098087)

Number of samples sequenced in each of the 3 sample sets (rows), after removal of siblings and contaminated samples. Autor Eric R. Lucas (6506420)

Primers of this study. Autor Shuang Li (146392)

Témata:

Agarose gel electrophoresis results of PCR products. Autor Shuang Li (146392)

Témata:

The degradation of PNP by <i>P</i>. <i>putida</i> DLL-E4, DLL-Δ<i>crc</i>, DLL-Δ<i>crc</i>Y, and DLL-Δ<i>crcZ</i>. Autor Shuang Li (146392)

Témata:

The growth of <i>P</i>. <i>putida</i> DLL-E4, DLL-Δ<i>crc</i>, DLL-Δ<i>crcY</i>, and DLL-Δ<i>crcZ</i> on LB medium. Autor Shuang Li (146392)

Témata:

Aggregated results for reported benefits and harms, stratified by leaflets and booklets. Autor Maren Dreier (628959)

“…<p>The figure indicates whether a leaflet contains <u>any</u> information on the benefits of CRC screening a) in general or specifically for b) colonoscopy or c) the FOBT, and whether it contains any information on the d) general and e) specific harms of colonoscopy. To be rated positive for harms, it was not sufficient if the only information about possible harms referred to pain, stating incorrectly that there is no pain involved.…”

Development of immune factors over visits in the AAF and AAF-syn treatment group as (A) scores and (B) loadings. Autor Diana M. Hendrickx (1507435)

Results of comparing visits within allergy groups using linear mixed models and post hoc analysis. Autor Diana M. Hendrickx (1507435)