Comparative transcriptomics of primary cells in vertebrates by Tanvir Alam (638619)

Comparative Analysis of Preterm and Full-term Births using Transcriptomic Profiling by Amal E. I. Ahmed (22789562)

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A curated transcriptome dataset collection to investigate inborn errors of immunity by Salim Bougarn (413372)

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Integrated Transcriptome and Pathway Analyses Revealed Multiple Activated Pathways in Breast Cancer by Radhakrishnan Vishnubalaji (3563306)

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Transcriptomic profile investigations highlight a putative role for NUDT16 in sepsis by Susie Shih Yin Huang (9112705)

“…A better understanding of the modulations of cellular processes in neutrophils and other blood cells during sepsis is needed and can be initiated via transcriptomic profile investigations. To that point, the growing repertoire of publicly accessible transcriptomic datasets serves as a valuable resource for discovering and/or assessing the robustness of biomarkers. …”

An interactive web application for exploring systemic lupus erythematosus blood transcriptomic diversity by Eléonore Bettacchioli (21842351)

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Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data by Mohammed Toufiq (7251596)

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Transcriptomic Analyses of Myeloid-Derived Suppressor Cell Subsets in the Circulation of Colorectal Cancer Patients by Varun Sasidharan Nair (5396393)

“…We have recently reported the transcriptomic profiles of tumor-infiltrating MDSCs in CRC patients and uncovered pathways, which could potentially assist tumor progression. …”

Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry by Jessica Roelands (7516439)

Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis by Susie S. Y. Huang (2824502)

“…This highly variable disease affects 19 million people globally, and accounts for 5 million deaths annually. In transcriptomic datasets curated from public repositories, we observed a consistent upregulation (3.26–5.29 fold) of ERLIN1—a gene coding for an ER membrane prohibitin and a regulator of inositol 1, 4, 5-trisphosphate receptors and sterol regulatory element-binding proteins—under septic conditions in healthy neutrophils, monocytes, and whole blood. …”

Integrated whole transcriptome and small RNA analysis revealed multiple regulatory networks in colorectal cancer by Hibah Shaath (5599658)

“…Herein, we performed microRNA (miRNA) sequencing on fifteen CRC and their non-tumor adjacent tissues and whole transcriptome RNA-Seq on six paired samples from the same cohort and identified alterations in miRNA, mRNA, and lncRNA expression. …”

A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification by Jessica Roelands (7516439)

“…In this note, we describe a curated compendium of 13 public datasets on human breast cancer, representing a total of 2142 transcriptome profiles. We classified the samples according to different immune based classification systems and integrated this information into the datasets. …”

Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles by Masri, Abdulkader

“…Backgrounds: Escherichia coli K1 causes neonatal meningitis. Transcriptome studies are indispensable to comprehend the pathology and biology of these bacteria. …”
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Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts by Georgess, Dan

“…We then performed two-step differential transcriptomic profiling of bone-resorbing OCs versus nonresorbing MGCs to generate a list of genes implicated in bone resorption. …”
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Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes by Radhakrishnan Vishnubalaji (3563306)

“…Integration of single-cell transcriptomic with CRISPR-Cas9 functional screen data identified 13 potential therapeutic targets for ER⁺, 44 potential therapeutic targets for HER2⁺, and 29 potential therapeutic targets for TNBC. …”

Transcriptomic Analyses Revealed Systemic Alterations in Gene Expression in Circulation and Tumor Microenvironment of Colorectal Cancer Patients by Hibah Shaath (5599658)

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Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology by Rawdhah M. Saleh (21436001)

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Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2 by Hibah Shaath (5599658)

“…In this study, we analyzed RNA-seq transcriptome data from Calu-3 human lung epithelial cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to five other viruses namely, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome (SARS-MERS), influenzavirus A (FLUA), influenzavirus B (FLUB), and rhinovirus (RHINO) compared to mock-infected cells and characterized their coding and noncoding RNA transcriptional portraits. …”

Comprehensive Transcriptomic Profiling of Murine Osteoclast Differentiation Reveals Novel Differentially Expressed Genes and LncRNAs by Salman M. Toor (8854751)

“…In this study, we performed comprehensive and progressive analyses of the dynamic transcriptomes of murine osteoclasts, generated in vitro. …”

A curated collection of transcriptome datasets to investigate the molecular mechanisms of immunoglobulin E-mediated atopic diseases by Susie S Y Huang (18805921)

“…The amount of publicly accessible transcriptomic data presents an unprecedented opportunity for mechanistic discoveries and validation of complex disease signatures across studies. …”