Development of a cerebral aneurysm segmentation method to prevent sentinel hemorrhage حسب Yousra Regaya (17788964)

Neuro-symbolic representation learning on biological knowledge graphs حسب Mona Alshahrani (3576653)

"…Results: We develop a novel method for feature learning on biological knowledge graphs. …"

Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology حسب Rawdhah M. Saleh (21436001)

"…The molecular heterogeneity of COAD demands robust computational strategies to improve the accuracy of biomarker discovery. </p><h3>Methods</h3><p dir="ltr">We developed and implemented a comprehensive, multi-step bioinformatics and statistical pipeline to systematically prioritize clinically relevant biomarkers in COAD. …"

Statistical methods and resources for biomarker discovery using metabolomics حسب Najeha R. Anwardeen (15184882)

DPI_CDF: druggable protein identifier using cascade deep forest حسب Muhammad Arif (769250)

"…</p><h3>Methods</h3><p dir="ltr">In this study, we developed a novel deep learning-based model DPI_CDF for predicting DPs based on protein sequence only. …"

COUSCOus: improved protein contact prediction using an empirical Bayes covariance estimator حسب Reda Rawi (391865)

"…Hence, new approaches and improvements of existing methods are needed to motivate further development and progress in the field. …"

The Role of a Facilitator in Co-Design Applications for Exploratory Analysis in Domains of High Complexity: The Case of MAHiCGO حسب Talar B. Yacoubian (16896378)

"…</p><h3>Methods</h3><p dir="ltr">We formed a design team comprising a visualization expert, a Human Computer Interaction (HCI) researcher, bioinformatics domain experts, and the Principal Investigator (PI) as a `facilitator' filling the communication gap between them. …"

Computational Methods for the Analysis and Prediction of EGFR-Mutated Lung Cancer Drug Resistance: Recent Advances in Drug Design, Challenges and Future Prospects حسب Rizwan Qureshi (15279193)

"…EGFR Tyrosine Kinase Inhibitors (TKIs) are developed to target the kinase domain of EGFR. These TKIs produce promising results at the initial stage of therapy, but the efficacy becomes limited due to the development of drug resistance. …"

OutSingle: a novel method of detecting and injecting outliers in RNA-Seq count data using the optimal hard threshold for singular values حسب Edin Salkovic (16891479)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Bioinformatics<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/bioinformatics/btad142" target="_blank">https://dx.doi.org/10.1093/bioinformatics/btad142</a></p>…"

Efficient experimental design for uncertainty reduction in gene regulatory networks حسب Roozbeh Dehghannasiri (5725805)

"…<h3>Background</h3><p dir="ltr">An accurate understanding of interactions among genes plays a major role in developing therapeutic intervention methods. Gene regulatory networks often contain a significant amount of uncertainty. …"

NSIT: Novel Sequence Identification Tool حسب Benjarath Pupacdi (635765)

Deep Learning in LncRNAome: Contribution, Challenges, and Perspectives حسب Tanvir Alam (638619)

Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer حسب Andrea Remo (447375)

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling of BMS-833923-treated compared to vehicle-treated control cells, identified 348 upregulated and 540 downregulated genes with significant effects on multiple signaling pathways, including GPCR, endochondral ossification, RANK-RANKL, insulin, TNF alpha, IL6, and inflammatory response. Further bioinformatic analysis employing Ingenuity Pathway Analysis revealed significant enrichment in BMS-833923-treated cells for a number of functional categories and networks involved in connective and skeletal tissue development and disorders, e.g., NFκB and STAT signaling. …"

Repurposing Nirmatrelvir for Hepatocellular Carcinoma: Network Pharmacology and Molecular Dynamics Simulations Identify HDAC3 as a Key Molecular Target حسب Muhammad Suleman (3829027)

Toward Preparing a Knowledge Base to Explore Potential Drugs and Biomedical Entities Related to COVID-19: Automated Computational Approach حسب Junaed Younus Khan (16870110)

Multimodal EEG and Keystroke Dynamics Based Biometric System Using Machine Learning Algorithms حسب Arafat Rahman (8065562)

A Convolutional Neural Network-Based Framework for Classification of Protein Localization Using Confocal Microscopy Images حسب Sonam Aggarwal (16904763)

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

"…Global gene expression profiling was conducted using the Agilent microarray platform, and data normalization and bioinformatics were performed using GeneSpring software. …"

Recent advances in Grey Wolf Optimizer, its versions and applications: Review حسب Abu Zitar, Raed

"…The Grey Wolf Optimizer (GWO) has emerged as one of the most captivating swarm intelligence methods, drawing inspiration from the hunting behavior of wolf packs. …"
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