A Phase 3 Trial Analysis Proposal for Mitigating the Impact of the COVID-19 Pandemic Por Eva Hua (10326765)

“...The trials had identical design, with four parallel treatment arms: two doses of active drug, an active comparator and placebo. ...”

All-Atom Multiscale Simulation of Cowpea Chlorotic Mottle Virus Capsid Swelling Por Yinglong Miao (1301934)

“...The capsid swelling is a symmetry-breaking process involving local initiation and front propagation. The capsid swelling rate is ∼0.25 nm/ns (npn) during the early stage of the simulation, and propagation of the structural transition across the capsid is roughly 0.6 npn. ...”

Effectiveness and acceptance of assistive technologies for people with tetraplegia: A systematic review Por Emanuel Nunez Sardinha (22511877)

“...From 1,670 initial records, 34 articles met inclusion criteria, involving 366 participants. Robotic arms, wearable exoskeletons, computer interfaces, powered wheelchairs, and functional electrical stimulation systems demonstrated varying effectiveness. ...”

Simultaneous and Independent Dual Site-Specific Self-Labeling of Recombinant Antibodies Por Carolin Wollschlaeger (553521)

“...Antibody-based diagnostic and therapeutic reagents armed with effector molecules such as dyes and drugs offer hope in the battle against cancer. ...”

Simultaneous and Independent Dual Site-Specific Self-Labeling of Recombinant Antibodies Por Carolin Wollschlaeger (553521)

“...Antibody-based diagnostic and therapeutic reagents armed with effector molecules such as dyes and drugs offer hope in the battle against cancer. ...”

All-Atom Multiscale Simulation of Cowpea Chlorotic Mottle Virus Capsid Swelling Por Yinglong Miao (1301934)

“...The capsid swelling is a symmetry-breaking process involving local initiation and front propagation. The capsid swelling rate is ∼0.25 nm/ns (npn) during the early stage of the simulation, and propagation of the structural transition across the capsid is roughly 0.6 npn. ...”

DataSheet_2_Sequence Diversity, Locus Structure, and Evolutionary History of the SpTransformer Genes in the Sea Urchin Genome.pdf Por Megan A. Barela Hudgell (11701967)

“...This theoretical evolutionary history is consistent with the involvement of these genes in the arms race in responses to pathogens and suggests that the diversification of these genes and their encoded proteins have been selected for based on the survival benefits of pathogen binding and host protection....”

DataSheet_1_Sequence Diversity, Locus Structure, and Evolutionary History of the SpTransformer Genes in the Sea Urchin Genome.pdf Por Megan A. Barela Hudgell (11701967)

“...This theoretical evolutionary history is consistent with the involvement of these genes in the arms race in responses to pathogens and suggests that the diversification of these genes and their encoded proteins have been selected for based on the survival benefits of pathogen binding and host protection....”

Intra-NAc CNO or Saline (SAL) infusions had no effect on locomotor activity or innate anxiety in hM4Di- or GFP-expressing (control) animals. Por Dylan Patterson (20615232)

“...<p>(<b>A</b>) Timeline of final set of experimental procedures involving locomotor activity test, elevated plus maze, and finally, open field test. ...”

Generation and characterization of MHV68 lacking the M2 ISRE (ISREΔ). Por Pratyusha Mandal (195674)

“...Purified BAC DNA was digested with SpeI and resolved by agarose gel electrophoresis. <b>(C–F)</b> Murine embryonic fibroblasts (MEFs, <b>(C, D)</b>) or bone marrow-derived macrophages (BMMs, <b>(E, F)</b>) from 129S2 mice were either untreated <b>(C, E)</b> or treated with 500 U/ml IFNβ <b>(D, F)</b> for 18 hours prior to infection with MHV68 or ISREΔ1 at a multiplicity of infection of 0.1 PFU per cell. ...”

High Resolution CZE-MS Quantitative Characterization of Intact Biopharmaceutical Proteins: Proteoforms of Interferon-β1 Por David R. Bush (1430062)

“...Given the high column efficiency, isobaric positional isomers of a single sialic acid on biantennary glycan antennae were resolved. Further, triantennary isomers (antenna on α(1–3) or α(1–6) arms) were separated and confirmed by exoglycosidase digestion. ...”

Are Japanese Randomized Controlled Trials Up to the Task? A Systematic Review Por Daisuke Yoneoka (394789)

“...Data were independently abstracted and assessed by two of the authors and disagreements were resolved by consensus. The quality of Japanese RCTs randomly sampled was assessed using the method guidelines for systematic reviews from the Cochrane Back Review Group. ...”

Linearity, depth resolution, and concentration quenching. Por Sangly P. Srinivas (1967464)

“...<p>Three solutions of fluorescein, prepared with PBS at 1, 10, and 50 μM (corresponding to 0.038%, 0.38%, and 1.88% (w/v), respectively) were contained in T-25 flasks. Depth-resolved fluorescence measurements were then obtained by positioning the flask along with the optical axis of the fluorometer. ...”

<em>HLA-A</em> Confers an <em>HLA-DRB1</em> Independent Influence on the Risk of Multiple Sclerosis Por Boel Brynedal (166203)

“...These findings imply complex autoimmune mechanisms involving both the regulatory and the effector arms of the immune system in the triggering of MS....”

Three Mexican Families with β thalassemia intermedia with different molecular basis Por Lourdes del Carmen Rizo de la Torre (8400954)

“...We report three Mexican families with beta thalassemia intermedia due to different molecular basis; a new single nucleotide mutation involving the last nucleotide of the β-globin chain transcript; and two possible new DNA rearrangements, an α cluster duplication, and a partial β gene deletion....”

Image_1_Case report: Overlap syndrome of neuromyelitis optica spectrum disorder with anti-Argonaute antibodies.jpeg Por Pei Liu (93392)

“...In this paper, we present the case of an adult woman with numbness, tingling, and burning sensations in her arms and subsequent bilateral internuclear ophthalmoplegia. ...”

Probing the Steric and Electronic Characteristics of a New Bis-Pyrrolide Pincer Ligand Por Nobuyuki Komine (1409530)

“...The electrochemistry of LM­(NCPh) and (L)­Zn­(DMAP) shows three oxidation processes, which is interpreted to involve at least two oxidations of the pyrrolide arms....”

Self-Optimizing Charge-Transfer Energy Phenomena in Metallosupramolecular Complexes by Dynamic Constitutional Self-Sorting Por Yves-Marie Legrand (1566367)

“...In this paper we report an extended series of 2,6-(iminoarene)pyridine-type Zn^II complexes [(L_ii)₂Zn]^II, which were surveyed for their ability to self-exchange both their ligands and their aromatic arms and to form different homoduplex and heteroduplex complexes in solution. ...”

Distribution-Free Prediction Intervals Under Covariate Shift, With an Application to Causal Inference Por Jing Qin (41397)

“...<p>Owing to its appealing distribution-free feature, conformal inference has become a popular tool for constructing prediction intervals with a desired coverage rate. In scenarios involving covariate shift, where the shift function needs to be estimated from data, many existing methods resort to data-splitting techniques. ...”

Image_2_Case report: Overlap syndrome of neuromyelitis optica spectrum disorder with anti-Argonaute antibodies.jpeg Por Pei Liu (93392)

“...In this paper, we present the case of an adult woman with numbness, tingling, and burning sensations in her arms and subsequent bilateral internuclear ophthalmoplegia. ...”