Structural rearrangement of the myosin subdomains along the rigor-like/post-rigor NMSM path; see also the corresponding sections in the text. od M. Cecchini (52536)

“…(E) Reorientation of the lever arm. The lever arm, the relay helix, and the SH1 helix are shown in yellow, red, and magenta, respectively. …”

Outcomes of stroke patients undergoing percutaneous endoscopic gastrostomy: a systematic review and meta-analysis od Mohammed Maan Al-Salihi (13105835)

“…A comparison of P.E.G. and N.G.T. in three studies involving 691 patients indicated a non-significant difference in-hospital mortality risk (R.R. = 0.59, 95% C.I. [0.2, 1.72]). …”

A Genetic and Structural Study of Genome Rearrangements Mediated by High Copy Repeat Ty1 Elements od Jason E. Chan (180060)

“…The majority of the <em>Ty912</em>-mediated GCRs observed were monocentric nonreciprocal translocations mediated by <em>RAD52</em>-dependent homologous recombination (HR) between <em>Ty912</em> and a Ty element on another chromosome arm. The remaining <em>Ty912</em>-mediated GCRs appeared to involve <em>Ty912</em>-mediated formation of unstable dicentric translocation chromosomes that were resolved by one or more Ty-mediated breakage-fusion-bridge cycles. …”

Schematic of a planar reaching experiment. od Dongwon Kim (6029939)

“…<p>The arm is modeled with a 2 degree-of-freedom (DOF) system involving the shoulder and elbow joints.…”

Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids od Timothy J. Mottram (4517953)

“…Additionally, we have determined that the N-terminal arm of N protein is not involved in N-L interactions. …”

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2 od Jessica D. Rosarda (11731866)

“…We demonstrate that AA147 activates NRF2 selectively in neuronal-derived cells through a mechanism involving metabolic activation to a reactive electrophile and covalent modification of KEAP1a mechanism analogous to that involved in the AA147-dependent activation of ATF6. …”

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2 od Jessica D. Rosarda (11731866)

“…We demonstrate that AA147 activates NRF2 selectively in neuronal-derived cells through a mechanism involving metabolic activation to a reactive electrophile and covalent modification of KEAP1a mechanism analogous to that involved in the AA147-dependent activation of ATF6. …”

Metadata supporting data files in the published article: The LISA randomized trial of a weight loss intervention in postmenopausal breast cancer od Pamela J. Goodwin (8382953)

“…The dataset includes disease-free survival, hazard ratios (HRs) for Disease-Free Survival (DFS) and Overall Survival (OS), baseline characteristics of the LISA study population, weight measurements at study entry (baseline), and change in weight during the subsequent 96 months, in patients enrolled onto the Lifestyle Intervention Arm and Education Only Arm.</div><div><br></div><div><b>Software needed to access data</b>: The SAS software is required to access the LISA.XPT dataset. …”

The polyamine transporter <i>Slc18b1(VPAT)</i> is important for both short and long time memory and for regulation of polyamine content in the brain od Robert Fredriksson (27811)

“…We found that this mouse has impaired short and long term memory in novel object recognition, radial arm maze and self-administration paradigms. We also show that <i>Slc18b1</i> KO mice have altered expression of genes involved in Long Term Potentiation, plasticity, calcium signalling and synaptic functions and that expression of components of GABA and glutamate signalling are changed. …”

Protein Markers for Insulin-Producing Beta Cells with Higher Glucose Sensitivity od Geert A. Martens (164886)

“…The proteome of the beta cell subpopulation with high metabolic and biosynthetic responsiveness to 7.5 mM glucose was characterized by <em>(i)</em> an on average 50% higher expression of protein biosynthesis regulators such as 40S and 60S ribosomal constituents, NADPH-dependent protein folding factors and translation elongation factors; <em>(ii)</em> 50% higher levels of enzymes involved in glycolysis and in the cytosolic arm of the malate/aspartate-NADH-shuttle. …”

Both Functional LTβ Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria od Dieudonnée Togbe (63760)

“…<div><h3>Background</h3><p>TNF-related lymphotoxin α (LTα) is essential for the development of <em>Plasmodium berghei</em> ANKA (PbA)-induced experimental cerebral malaria (ECM). The pathway involved has been attributed to TNFR2. Here we show a second arm of LTα-signaling essential for ECM development through LTβ-R, receptor of LTα1β2 heterotrimer.…”

Image_1_Sequence Read Depth Analysis of a Monophyletic Cluster of Y Chromosomes Characterized by Structural Rearrangements in the AZFc Region Resulting in DYS448 Deletion and DYF38... od Francesco Ravasini (10657496)

“…<p>The azoospermia factor c region (AZFc), located in the long arm of the human Y chromosome, is frequently involved in chromosome rearrangements, mainly due to non-allelic homologous recombination events that occur between the nearly identical sequences (amplicon) that comprises it. …”

Image 2_Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling.tif od Michael Young (40123)

“…In addition, the diacylglycerol arm of the signaling pathway was investigated with protein kinase C (PKC) inhibitors and siRNA knockdown. …”

The Cohesion Protein SOLO Associates with SMC1 and Is Required for Synapsis, Recombination, Homolog Bias and Cohesion and Pairing of Centromeres in Drosophila Meiosis od Rihui Yan (434740)

“…In this study, we show that <i>solo</i> is involved in multiple aspects of meiosis in female Drosophila. …”

Image 5_Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling.tif od Michael Young (40123)

“…In addition, the diacylglycerol arm of the signaling pathway was investigated with protein kinase C (PKC) inhibitors and siRNA knockdown. …”

Neurospora Importin α Is Required for Normal Heterochromatic Formation and DNA Methylation od Andrew D. Klocko (707797)

“…Surprisingly, nuclear transport of all known proteins involved in histone and DNA methylation, as well as a canonical transport substrate, appear normal in <i>dim-3</i> strains. …”

DataSheet_1_Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC.zip od Fang Ke (222967)

“…The results suggested that quercetin could alleviate LPS-induced depression-like behaviors and impairment of learning and memory in rats, the mechanism of which might be involved with regulating the BDNF-related imbalance expression of Copine 6 and TREM1/2 in the hippocampus and the PFC.…”

Data_Sheet_1_Effectiveness of online advanced C.A.R.E suicide prevention gatekeeper training program among healthcare lecturers and workers in national university of Malaysia: A pi... od Amran Fadzrul Roslan (14456124)

“…</p>Methods<p>A single-arm interventional pre-and post-pilot study was conducted on a sample of healthcare lecturers and workers who are involved in supervising healthcare students. …”

Table_1_Effect of intermittent theta burst stimulation on upper limb function in stroke patients: a systematic review and meta-analysis.docx od Junyue Lu (18570118)

“…</p>Results<p>The study included a total of 9 trials and involved 224 patients. The results demonstrate that compared to the control group, iTBS therapy significantly improved Fugl-Meyer assessment-upper extremity (FMA-UE) scores (SMD = 0.88; 95% CI = 0.11–1.66; P = 0.03, I² = 84%), Action Research Arm Test (ARAT) scores (SMD = 0.83; 95% CI = 0.16–1.50; P = 0.02, I² = 57%), and Barthel Index (BI) scores (SMD = 0.93; 95% CI = 0.53–1.32; P < 0.0001, I² = 0%) in stroke patients.…”

Image_2_QTL for induced resistance against leaf rust in barley.jpeg od Andrea Matros (2301088)

“…Therefore, the present study aims to detect genotypic differences in the response of barley to AHL, followed by the identification of genomic regions involved in priming efficiency of barley. A diverse set of 198 spring barley accessions was treated with a repaired E. meliloti natural mutant strain expR+ch producing a substantial amount of AHL and a transformed E. meliloti strain carrying the lactonase gene attM from Agrobacterium tumefaciens. …”