Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats per P.G. Carvalho-Costa (6543350)

“…Additionally, several lines of evidence have suggested that the LC can be involved in the modulation of emotional states such as fear and anxiety. …”

Table_7_New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.XLSX per Wiebke Haeger (10921239)

“…Phylogenetic analysis revealed that PGIP-like proteins clustered apart from “classical” PGIPs but together with proteins, which have been involved in developmental processes. Our results indicate that PGIP-like proteins represent not only interesting novel PG inhibitor candidates in addition to “classical” PGIPs, but also fascinating new players in the arms race between herbivorous beetles and plant defenses.…”

Table_6_New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.XLSX per Wiebke Haeger (10921239)

“…Phylogenetic analysis revealed that PGIP-like proteins clustered apart from “classical” PGIPs but together with proteins, which have been involved in developmental processes. Our results indicate that PGIP-like proteins represent not only interesting novel PG inhibitor candidates in addition to “classical” PGIPs, but also fascinating new players in the arms race between herbivorous beetles and plant defenses.…”

Table_4_New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.XLSX per Wiebke Haeger (10921239)

“…Phylogenetic analysis revealed that PGIP-like proteins clustered apart from “classical” PGIPs but together with proteins, which have been involved in developmental processes. Our results indicate that PGIP-like proteins represent not only interesting novel PG inhibitor candidates in addition to “classical” PGIPs, but also fascinating new players in the arms race between herbivorous beetles and plant defenses.…”

Table_3_New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.XLSX per Wiebke Haeger (10921239)

“…Phylogenetic analysis revealed that PGIP-like proteins clustered apart from “classical” PGIPs but together with proteins, which have been involved in developmental processes. Our results indicate that PGIP-like proteins represent not only interesting novel PG inhibitor candidates in addition to “classical” PGIPs, but also fascinating new players in the arms race between herbivorous beetles and plant defenses.…”

Table_1_New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.XLSX per Wiebke Haeger (10921239)

“…Phylogenetic analysis revealed that PGIP-like proteins clustered apart from “classical” PGIPs but together with proteins, which have been involved in developmental processes. Our results indicate that PGIP-like proteins represent not only interesting novel PG inhibitor candidates in addition to “classical” PGIPs, but also fascinating new players in the arms race between herbivorous beetles and plant defenses.…”

Penetration Tests Data for Concrete Setting Evolution per Sina Akhbari (17916656)

“…</p><p dir="ltr">Experiments used a UR-series industrial arm carrying a Mecmesin VFG force gauge fitted with a 60° conical needle. …”

Supplementary materials: Comparative efficacy of diroximel fumarate, ozanimod and interferon beta-1a for relapsing multiple sclerosis using matching-adjusted indirect comparisons per Tammy Jiang (19441675)

“…<b>Patients & methods:</b> We used individual patient data from EVOLVE-MS-1 (NCT02634307), a 2-year, open-label, single-arm, phase III study of DRF (n = 1057) and aggregate data from RADIANCE (NCT02047734), a 2-year, double-blind, phase III study that compared OZA 1 mg once daily (n = 433) and intramuscular IFN 30 μg once weekly (n = 441). …”

Supplementary Material for: Demographic Gaps and Requirements for Participation: A Systematic Review of Clinical Trial Designs in Hidradenitis Suppurativa per James J.F. (13800745)

“…Title and abstract screening and data extraction were completed by two independent reviewers, with disagreements resolved by a third. <b><i>Results:</i></b> Twenty-three studies totaling 1,496 adult participants met the inclusion criteria. …”

The CP_C NTA forms an extensive network at the capsid interior that includes a β-annulus motif. per Kok Lian Ho (2049103)

“…<i>rosenbergii</i> nodavirus; NTA, N-terminal arm; P domain, protruding domain; S domain, shell domain.…”

DSB Formation and RAD-51 Loading in the <i>rec-8</i> Mutant Background per Michiko Hayashi (81344)

“…</p><p>(B) Each panel shows the full karyotype in a single oocyte nucleus of the indicated genotype, either at the late diplotene/early diakinesis stage (left two panels, stained with DAPI [blue] and RAD-51 antibody [green]) or at late diakinesis (stained with DAPI in white; images shown are from the most mature oocyte in the gonad arm, in the −1 position immediately adjacent to the spermatheca). …”

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in <i>Onchocerca volvulus</i> Infection per Kwablah Awadzi (169148)

“…Statistically significantly higher percentages of participants treated with 8 mg moxidectin than participants treated with ivermectin experienced pruritus (87% vs. 56%), rash (63% vs. 42%), increased pulse rate (61% vs. 36%) and decreased mean arterial pressure upon 2 minutes standing still after ≥5 minutes supine relative to pre-treatment (61% vs. 27%). These reactions resolved without treatment. In the 8 mg moxidectin and ivermectin arms, the mean±SD number of microfilariae/mg skin were 22.9±21.1 and 21.2±16.4 pre-treatment and 0.0±0.0 and 1.1±4.2 at nadir reached 1 and 3 months after treatment, respectively. …”

Demographic data and baseline characteristics. per Shyam Sundar (58354)

“…</p><p>Methodology/Principal findings</p><p>An open-label, phase II, randomized, parallel-arm, non-comparative trial was conducted in patients with parasitologically confirmed PKDL, 6 to ≤60 years. …”

Participant flow chart. per Shyam Sundar (58354)

“…</p><p>Methodology/Principal findings</p><p>An open-label, phase II, randomized, parallel-arm, non-comparative trial was conducted in patients with parasitologically confirmed PKDL, 6 to ≤60 years. …”

Supplementary Material for: Comparative Cytogenetic Analysis of Three Eumeninae Species (Hymenoptera, Vespidae) per Tavares M.G. (10788123)

“…Based on the cytogenetic data obtained here, we discuss the possible numerical/structural rearrangements that may be involved in the karyotypic evolution of the 3 studied species. …”

Image_1_The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease.pdf per Gonzalo R. Acevedo (4050676)

“…<p>Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune response in a very complex and flowery manner. …”

Efficacy and Safety of ‘Fixed Dose’ versus ‘Loose’ Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial... per Abraham Aseffa (108981)

“…</p><p>Methods</p><p>A two-arm, single-blind, randomized clinical trial comparing FDCs with separate LFs involving 1000 adults newly diagnosed with culture positive PTB was conducted at five sites in two African countries between 2007 and 2011. …”

DataSheet_1_Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring... per Thomas Powles (3502598)

“…Current methods often involve germline sampling, which is not always feasible or practical. …”

DataSheet_1_A Prospective Investigation of Bispecific CD19/22 CAR T Cell Therapy in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma.zip per Ying Zhang (40767)

“…</p>Methods<p>We performed a prospective, single-arm study of bispecific CD19/22 CAR T cells in R/R B-NHL. …”

Text S1 - Considering Usual Medical Care in Clinical Trial Design per Liza Dawson (259048)

“…The meeting was informed by a background paper outlining types of challenges involved in selecting usual care arms, prepared by a working group with expertise in clinical trial design, ethics, evidence-based medicine, statistics, and science policy. …”