High Resolution CZE-MS Quantitative Characterization of Intact Biopharmaceutical Proteins: Proteoforms of Interferon-β1 по David R. Bush (1430062)

“...Given the high column efficiency, isobaric positional isomers of a single sialic acid on biantennary glycan antennae were resolved. Further, triantennary isomers (antenna on α(1–3) or α(1–6) arms) were separated and confirmed by exoglycosidase digestion. ...”

Are Japanese Randomized Controlled Trials Up to the Task? A Systematic Review по Daisuke Yoneoka (394789)

“...Surgical intervention studies for external causes of morbidity and mortality with a large sample size, trial registration and a large number of arms were most likely to be of higher quality.</p><p>Conclusion</p><p>Despite a considerable number of RCTs conducted in Japan, their quality is not satisfactory in some domains. ...”

Linearity, depth resolution, and concentration quenching. по Sangly P. Srinivas (1967464)

“...The angle between the excitation and the emission arms was held at 45°. Concentrations of fluorescein in % (provided in parenthesis) are in w/v basis. ...”

Novel Drosophila Viruses Encode Host-Specific Suppressors of RNAi по Joël T. van Mierlo (142169)

“...It has been suggested that an evolutionary ‘arms race’ may occur between rapidly evolving components of the antiviral RNAi pathway of <i>Drosophila</i> and viral genes that antagonize it. ...”

Evidence for a Common Toolbox Based on Necrotrophy in a Fungal Lineage Spanning Necrotrophs, Biotrophs, Endophytes, Host Generalists and Specialists по Marion Andrew (188899)

“...Consistent with an evolutionary arms race model, positive selection was detected in 5 of 8 genes. ...”

Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape по Dustin C. Hancks (268962)

“...PRRs directly engaged by pathogen inhibitors often evolve under recurrent bouts of positive selection that have been described as molecular ‘arms races.’ ...”

Table_1.XLSX по Shigeko Kimura (4921186)

“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”

Main spider species of medical significance in the Brazilian Amazon. по Vanderson Souza Sampaio (3167037)

“...<p><i>Phoneutria fera</i> (A) and <i>Phoneutria reydii</i> (B), commonly known as Brazilian wandering spiders, armed spiders ("armadeiras", as they are known in Brazilian Portuguese), or banana spiders, are a genus of aggressive spiders of the Ctenidae family, with potential medical significance to humans due to their neurotoxic venom. ...”

Table_3.xlsx по Shigeko Kimura (4921186)

“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”

Controlled Chaos of Polymorphic Mucins in a Metazoan Parasite <em>(Schistosoma mansoni)</em> Interacting with Its Invertebrate Host <em>(Biomphalaria glabrata)</em> по Emmanuel Roger (269378)

“...Consequently, the generally accepted arms race hypothesis predicts that molecular diversity and polymorphism also exist in parasites of invertebrates. ...”

Table_2.XLSX по Shigeko Kimura (4921186)

“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”

Image_1.PDF по Shigeko Kimura (4921186)

“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”

Loss of ISWI Results in Defects in Chromatin Assembly по Davide F. V Corona (75522)

“...Wild-type (WT) chromosomes immunostained with a pan-histone antibody (MAB052), which has been described as staining all histones, exhibit uniform histone staining of all arms. <i>Iswi¹</i>/<i>Iswi²</i> male autosomes were uniformly stained, while staining of the X chromosome was dramatically reduced (arrowheads). ...”

Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines по Lamberto Manzoli (206725)

“...Finally, the rate of serious vaccine-related adverse events was low for all 2009 H1N1 vaccines (3 cases, resolved in 10 days, out of 22826 vaccinated subjects). ...”

THR depletion causes failure of chromosomal MNM/SNM release and homolog separation during meiosis I. по Ariane C. Blattner (2633800)

“...Time in minutes is indicated in the lower right corner of the merged images with t = 0 representing the time when chromatin decondensation had progressed to the point where chromosome arms could no longer be resolved individually. In the control (+), the last metaphase I frame was at -9 minutes and the MNM-EGFP dot disappeared within the first 3 minutes of anaphase I. ...”

Metadata supporting data files in the published article: DNA Methylation Markers Predict Recurrence-free Interval in Triple- Negative Breast Cancer по MaryJo Fackler (8134182)

“...</p> <p><b> </b></p> <p><b>Study approval: </b>All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. ...”

Endogenous nutrient stores correlate with the CPI-613 response <i>in vitro</i> and <i>in vivo</i>. по Moises O. Guardado Rivas (12837125)

“...Note that other cell death studies herein generally involve longer incubation times and, thus, stronger responses....”

DataSheet_6_Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens.pdf по Victoria I. Verhoeve (8998307)

“...Mammalian pathogenicity evolved from basal, non-pathogenic host-associations; however, some non-pathogens are closely related to pathogens. ...”

DataSheet_1_Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens.pdf по Victoria I. Verhoeve (8998307)

“...Mammalian pathogenicity evolved from basal, non-pathogenic host-associations; however, some non-pathogens are closely related to pathogens. ...”

DataSheet_10_Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens.pdf по Victoria I. Verhoeve (8998307)

“...Mammalian pathogenicity evolved from basal, non-pathogenic host-associations; however, some non-pathogens are closely related to pathogens. ...”