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2901
Video1_Case report: Pylorus-preserving pancreatoduodenectomy for focal congenital hyperinsulinism in a 5-month-old baby.avi
Опубліковано 2023“...</p>Conclusions<p>Surgical treatment of medical unresponsive focal forms of CHI is feasible in very small children: it is mandatory to refer the baby to a high-volume centre for a multidisciplinary management involving hepato-bilio-pancreatic surgeons and experts in metabolic disease....”
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2902
Genome-Wide Comparison of Cowpox Viruses Reveals a New Clade Related to Variola Virus
Опубліковано 2013“...Therefore, 22 genomes of independent CPXV strains from clinical cases, involving ten humans, four rats, two cats, two jaguarundis, one beaver, one elephant, one marah and one mongoose, were sequenced by using massive parallel pyrosequencing. ...”
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2903
Interlocking Molecular Gear Chains Built on Surfaces
Опубліковано 2018“...These studies therefore allow better informed design of future molecular machine components involving motors, gears, axles, etc....”
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2904
Transposition Is Targeted to Structures, Not Sequences
Опубліковано 2013“...One plasmid stably maintains a linear inverted repeat; the other forms a stable cruciform, with two extruded hairpin arms.</p> <p>(B) Transposition is stimulated by cruciform structures. ...”
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2905
Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs
Опубліковано 2022“...During this evolutionary arms race between human and virus, SARS-CoV-2 tries to improve its <i>cis</i> elements to compete with host RNAs for rapid translation....”
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2906
DataSheet_1_Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.docx
Опубліковано 2022“...A systematic review and frequency network meta-analysis were then performed for cardiotoxicity events. 91 RCTs (n=52247) involving 12 treatment arms were finally included. ...”
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2907
Supplementary Material for: Effect and Safety of Remifentanil Patient-Controlled Analgesia Compared with Epidural Analgesia in Labor: An Updated Meta-Analysis of Randomized Control...
Опубліковано 2021“...The routine use of rPCA in labor must be armed with close respiratory monitoring. Continued well-designed studies are required to provide more robust evidence....”
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2908
Inhibition of the STAT3 Protein by a Dinuclear Macrocyclic Complex
Опубліковано 2016“...Treatment of whole cells with the inhibitor revealed that it is bioactive in living cells and has oncostatic properties that could be interesting for the fight against cancer and other pathologies involving the STAT3 protein....”
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2909
Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes
Опубліковано 2021“...Type 1 diabetes has a multifactorial autoimmune etiology, involving environmental prompts and polygenic predisposition. ...”
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2910
Database from <b>Factors affecting front-line host defences against avian brood parasitism: a meta-analysis</b>
Опубліковано 2025“...This behaviour triggers a coevolutionary arms race, driving the evolution of host defences and parasite counter-defences. ...”
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2911
Deciphering the Structural Enigma of HLA Class-II Binding Peptides for Enhanced Immunoinformatics-based Prediction of Vaccine Epitopes
Опубліковано 2020“...CD4 T-cell-based peptide vaccines involve immunization with antigenic determinants from pathogens or neoplastic cells that possess the ability to elicit a robust T helper cell response, which subsequently activates other arms of the immune system. ...”
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2912
Image_1_Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.tif
Опубліковано 2024“...Introduction<p>The involvement of endocannabinoid system (ECS) in the inflammatory cascade, and the ability of phytocannabinoids, endocannabinoids and their synthetic analogues to modulate it has become an interesting research area for new therapeutic approaches in inflammatory skin diseases. ...”
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2913
Deciphering the Structural Enigma of HLA Class-II Binding Peptides for Enhanced Immunoinformatics-based Prediction of Vaccine Epitopes
Опубліковано 2020“...CD4 T-cell-based peptide vaccines involve immunization with antigenic determinants from pathogens or neoplastic cells that possess the ability to elicit a robust T helper cell response, which subsequently activates other arms of the immune system. ...”
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2914
Separase Is Required for Homolog and Sister Disjunction during <i>Drosophila melanogaster</i> Male Meiosis, but Not for Biorientation of Sister Centromeres
Опубліковано 2016“...To characterize a potential involvement of separase in sister centromere individualization before meiosis II, we have studied meiosis in <i>Drosophila melanogaster</i> males where homologs are not paired in the canonical manner. ...”
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2915
The novel multi-cytokine inhibitor TO-207 specifically inhibits pro-inflammatory cytokine secretion in monocytes without affecting the killing ability of CAR T cells
Опубліковано 2020“...<div><p>Cancer immunotherapy using chimeric antigen receptor–armed T (CAR T) cells have been shown to improve outcomes significantly in patients with hematological malignancies. ...”
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2916
Cytological analysis of HeLa cells expressing non-cleavable (NC) Rad21.
Опубліковано 2007“...NC-Rad21: (F–G) Delayed nucleolus disassembly in early prometaphase and delayed sister chromatid resolution (56% of prometaphases had the resolution defect); (H–I) Late prometaphase and metaphase cells with unresolved sisters (32%); (J) Metaphase – polar view; (K–L) Aberrant anaphases – centromere regions separating before arms (arrows) and some chromosomes segregating to the poles before other chromosomes have separated their sisters (28% were abnormal based on these criteria); (M) Cut telophase (26% of the telophases had this phenotype); (N) Apolar telophase (16% of the telophases had this phenotype); (O) Partially resolved diplochromosomes (5% of mitotics), in agreement with the described separase RNAi phenotype <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000318#pone.0000318-GimnezAbin3" target="_blank">[41]</a>; (P–T) DNA (DAPI; blue) and CREST (green) staining of kinetochores after NC-Rad21 induction. ...”
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2917
Table1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.docx
Опубліковано 2023“...These symptoms were completely resolved in the following days without residual neurological complications. ...”
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2918
Comparison of capsid-binding patterns of CATC in MCMV and HCMV.
Опубліковано 2019“...Except for triplex Tc (highlighted in yellow), two pM32nt subunits form a “Λ”-shaped density (cyan and orange-red) acts like a stayed cable, with each of its two arms holding to a neighboring hexon/penton capsomer and its vertex sitting atop a triplex. ...”
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2919
Genome-wide association analysis of eclosion on MeHg with and without caffeine supplementation.
Опубліковано 2014“...Depicted is a heat map for linkage disequilibrium (LD) based on <i>r<sup>2</sup></i> values where the black bars represent the five major <i>Drosophila</i> chromosome arms. Red indicates high LD, while blue indicates low LD. ...”
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2920
Video1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.avi
Опубліковано 2023“...These symptoms were completely resolved in the following days without residual neurological complications. ...”