Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs od Lin Zhu (192179)

“…During this evolutionary arms race between human and virus, SARS-CoV-2 tries to improve its <i>cis</i> elements to compete with host RNAs for rapid translation.…”

DataSheet_1_Cardiotoxicity of immune checkpoint inhibitors: A frequency network meta-analysis.docx od Maobai Liu (9732134)

“…A systematic review and frequency network meta-analysis were then performed for cardiotoxicity events. 91 RCTs (n=52247) involving 12 treatment arms were finally included. …”

Supplementary Material for: Effect and Safety of Remifentanil Patient-Controlled Analgesia Compared with Epidural Analgesia in Labor: An Updated Meta-Analysis of Randomized Control... od Zhang P. (4052710)

“…The routine use of rPCA in labor must be armed with close respiratory monitoring. Continued well-designed studies are required to provide more robust evidence.…”

Inhibition of the STAT3 Protein by a Dinuclear Macrocyclic Complex od Lígia M. Mesquita (2567752)

“…Treatment of whole cells with the inhibitor revealed that it is bioactive in living cells and has oncostatic properties that could be interesting for the fight against cancer and other pathologies involving the STAT3 protein.…”

Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes od Helmut Hiller (10818276)

“…Type 1 diabetes has a multifactorial autoimmune etiology, involving environmental prompts and polygenic predisposition. …”

Database from <b>Factors affecting front-line host defences against avian brood parasitism: a meta-analysis</b> od Mari Carmen López Luengo (22377922)

“…This behaviour triggers a coevolutionary arms race, driving the evolution of host defences and parasite counter-defences. …”

Deciphering the Structural Enigma of HLA Class-II Binding Peptides for Enhanced Immunoinformatics-based Prediction of Vaccine Epitopes od Deepyan Chatterjee (5534177)

“…CD4 T-cell-based peptide vaccines involve immunization with antigenic determinants from pathogens or neoplastic cells that possess the ability to elicit a robust T helper cell response, which subsequently activates other arms of the immune system. …”

Image_1_Cannabidiol exerts multitarget immunomodulatory effects on PBMCs from individuals with psoriasis vulgaris.tif od Cristina Pagano (113982)

“…Introduction<p>The involvement of endocannabinoid system (ECS) in the inflammatory cascade, and the ability of phytocannabinoids, endocannabinoids and their synthetic analogues to modulate it has become an interesting research area for new therapeutic approaches in inflammatory skin diseases. …”

Deciphering the Structural Enigma of HLA Class-II Binding Peptides for Enhanced Immunoinformatics-based Prediction of Vaccine Epitopes od Deepyan Chatterjee (5534177)

“…CD4 T-cell-based peptide vaccines involve immunization with antigenic determinants from pathogens or neoplastic cells that possess the ability to elicit a robust T helper cell response, which subsequently activates other arms of the immune system. …”

Separase Is Required for Homolog and Sister Disjunction during <i>Drosophila melanogaster</i> Male Meiosis, but Not for Biorientation of Sister Centromeres od Ariane C. Blattner (2633800)

“…To characterize a potential involvement of separase in sister centromere individualization before meiosis II, we have studied meiosis in <i>Drosophila melanogaster</i> males where homologs are not paired in the canonical manner. …”

The novel multi-cytokine inhibitor TO-207 specifically inhibits pro-inflammatory cytokine secretion in monocytes without affecting the killing ability of CAR T cells od Muneyoshi Futami (8748561)

“…<div><p>Cancer immunotherapy using chimeric antigen receptor–armed T (CAR T) cells have been shown to improve outcomes significantly in patients with hematological malignancies. …”

Cytological analysis of HeLa cells expressing non-cleavable (NC) Rad21. od Laura A. Díaz-Martínez (67557)

“…NC-Rad21: (F–G) Delayed nucleolus disassembly in early prometaphase and delayed sister chromatid resolution (56% of prometaphases had the resolution defect); (H–I) Late prometaphase and metaphase cells with unresolved sisters (32%); (J) Metaphase – polar view; (K–L) Aberrant anaphases – centromere regions separating before arms (arrows) and some chromosomes segregating to the poles before other chromosomes have separated their sisters (28% were abnormal based on these criteria); (M) Cut telophase (26% of the telophases had this phenotype); (N) Apolar telophase (16% of the telophases had this phenotype); (O) Partially resolved diplochromosomes (5% of mitotics), in agreement with the described separase RNAi phenotype <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000318#pone.0000318-GimnezAbin3" target="_blank">[41]</a>; (P–T) DNA (DAPI; blue) and CREST (green) staining of kinetochores after NC-Rad21 induction. …”

Table1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.docx od Weishang Song (17661528)

“…These symptoms were completely resolved in the following days without residual neurological complications. …”

Comparison of capsid-binding patterns of CATC in MCMV and HCMV. od Wei Liu (20030)

“…Except for triplex Tc (highlighted in yellow), two pM32nt subunits form a “Λ”-shaped density (cyan and orange-red) acts like a stayed cable, with each of its two arms holding to a neighboring hexon/penton capsomer and its vertex sitting atop a triplex. …”

Genome-wide association analysis of eclosion on MeHg with and without caffeine supplementation. od Sara L. Montgomery (652586)

“…Depicted is a heat map for linkage disequilibrium (LD) based on <i>r²</i> values where the black bars represent the five major <i>Drosophila</i> chromosome arms. Red indicates high LD, while blue indicates low LD. …”

Video1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.avi od Weishang Song (17661528)

“…These symptoms were completely resolved in the following days without residual neurological complications. …”

Model for the variable pathways utilized by divergent <i>Rickettsia</i> species for host cell entry. od Kristen E. Rennoll-Bankert (785434)

“…The divergent distal arms of this pathway involve recruitment of factors for activating the actin nucleating complex (Arp2/3), which leads to host actin polymerization, extensive membrane ruffling and filopodia formation, and bacterial internalization in a clathrin and calveolin dependent process. …”

Table_1_Multifractal Dynamics in Executive Control When Adapting to Concurrent Motor Tasks.DOCX od Laurent M. Arsac (5563346)

“…Here by recruiting elite rugby players with high motor skills and submitting them to the execution of rhythmic motor tasks involving legs and arms concurrently, the main attempt was to build on the multifractal formalism of movement control to show a marginal need of effective adaptation in concurrent tasks, and a preserved adaptability despite complexified motor execution. …”

Table 2_Efficacy of various plant-derived interventions in the prevention of radiation dermatitis in breast cancer patients: a systematic review and network meta-analysis of random... od Mingyu Li (482173)

“…</p>Results<p>In our NMA, we included 18 RCTs involving 2177 patients and 18 different treatment arms. …”

Image 1_Efficacy of various plant-derived interventions in the prevention of radiation dermatitis in breast cancer patients: a systematic review and network meta-analysis of random... od Mingyu Li (482173)

“…</p>Results<p>In our NMA, we included 18 RCTs involving 2177 patients and 18 different treatment arms. …”