The novel multi-cytokine inhibitor TO-207 specifically inhibits pro-inflammatory cytokine secretion in monocytes without affecting the killing ability of CAR T cells by Muneyoshi Futami (8748561)

“…<div><p>Cancer immunotherapy using chimeric antigen receptor–armed T (CAR T) cells have been shown to improve outcomes significantly in patients with hematological malignancies. …”

Models for regulation of chromosome cohesion in mitosis and meiosis. by Jonathan M. G. Higgins (463395)

“…<p>(A) In mitosis, cohesin (red rings) is phosphorylated and removed from chromosome arms by the “prophase pathway.” …”

RNA∶DNA Hybrids Initiate Quasi-Palindrome-Associated Mutations in Highly Transcribed Yeast DNA by Nayun Kim (481079)

“…<div><p>RNase H enzymes promote genetic stability by degrading aberrant RNA∶DNA hybrids and by removing ribonucleotide monophosphates (rNMPs) that are present in duplex DNA. …”

Cohesin release is delayed in <i>Atwapl1-1wapl2</i> meiocytes. by Kuntal De (599822)

“…Meiocytes in wild-type and <i>Atwapl1-1wapl2</i> plants exhibited similar SYN1 staining at zygotene (A, G) and pachytene (B, H). SYN1 is removed from the arms of wild type meiocytes during diplotene (C) and diakinesis (D) and is not detectable during metaphase I and anaphase I (E, F). …”

Strategy for STAG2 gene correction in VM-CUB-3 cells. by Youngrok Park (14930814)

“…An AAV-based gene editing vector was generated in which ~1 kb homology arms composed of wild-type STAG2 genomic sequence flank a FLOXed IRES-neo^R gene. …”

Image_1_Nucleoprotein of a Rice Rhabdovirus Serves as the Effector to Attenuate Hemolymph Melanization and Facilitate Viral Persistent Propagation in its Leafhopper Vector.pdf by Ruonan Zhang (358761)

“…Our findings provide the insights in the understanding of ongoing arms race of insect immunity defense and viral counter-defense.…”

Table 1_Olfactometer-measured responses of Listronotus bonariensis (Kuschel) (Coleoptera: Curculionidae) to feeding-induced grass volatiles and conspecific frass as influenced by t... by Jessica Vereijssen (4063189)

“…<p>This contribution aimed to uncover the unique host plant-finding and spatial ecology of reproductive and diapausing Argentine stem weevil, Listronotus bonariensis, and its adaptive implications in Aotearoa-New Zealand pasture. Still-air two-armed olfactometers revealed the reproductive and diapausing L. bonariensis preferences for plant and weevil-derived volatiles. …”

Human Collective Intelligence under Dual Exploration-Exploitation Dilemmas by Wataru Toyokawa (587730)

“…Colonies of eusocial insects are known to solve this dilemma successfully via evolved coordination mechanisms that function at the collective level. …”

CRISPR Associated Diversity within a Population of <em>Sulfolobus islandicus</em> by Nicole L. Held (181891)

“…<div><h3>Background</h3><p>Predator-prey models for virus-host interactions predict that viruses will cause oscillations of microbial host densities due to an arms race between resistance and virulence. A new form of microbial resistance, CRISPRs (clustered regularly interspaced short palindromic repeats) are a rapidly evolving, sequence-specific immunity mechanism in which a short piece of invading viral DNA is inserted into the host's chromosome, thereby rendering the host resistant to further infection. …”

Strategies 1 to 3 for MLF knock out. by Zi-Qi Lin (6444350)

“…In another experiment, puromycin was removed from the Cas9MLFko cell line to obtain the Cas9MLFko–pu cell line. …”

Cytological analysis of HeLa cells expressing non-cleavable (NC) Rad21. by Laura A. Díaz-Martínez (67557)

“…NC-Rad21: (F–G) Delayed nucleolus disassembly in early prometaphase and delayed sister chromatid resolution (56% of prometaphases had the resolution defect); (H–I) Late prometaphase and metaphase cells with unresolved sisters (32%); (J) Metaphase – polar view; (K–L) Aberrant anaphases – centromere regions separating before arms (arrows) and some chromosomes segregating to the poles before other chromosomes have separated their sisters (28% were abnormal based on these criteria); (M) Cut telophase (26% of the telophases had this phenotype); (N) Apolar telophase (16% of the telophases had this phenotype); (O) Partially resolved diplochromosomes (5% of mitotics), in agreement with the described separase RNAi phenotype <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0000318#pone.0000318-GimnezAbin3" target="_blank">[41]</a>; (P–T) DNA (DAPI; blue) and CREST (green) staining of kinetochores after NC-Rad21 induction. …”

Table1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.docx by Weishang Song (17661528)

“…These symptoms were completely resolved in the following days without residual neurological complications. …”

Comparison of capsid-binding patterns of CATC in MCMV and HCMV. by Wei Liu (20030)

“…Except for triplex Tc (highlighted in yellow), two pM32nt subunits form a “Λ”-shaped density (cyan and orange-red) acts like a stayed cable, with each of its two arms holding to a neighboring hexon/penton capsomer and its vertex sitting atop a triplex. …”

Genome-wide association analysis of eclosion on MeHg with and without caffeine supplementation. by Sara L. Montgomery (652586)

“…Depicted is a heat map for linkage disequilibrium (LD) based on <i>r²</i> values where the black bars represent the five major <i>Drosophila</i> chromosome arms. Red indicates high LD, while blue indicates low LD. …”

Video1_Delayed lethal central nervous system toxicity induced by a low-dose intrathecal administration of bupivacaine: case report.avi by Weishang Song (17661528)

“…These symptoms were completely resolved in the following days without residual neurological complications. …”

Model for the variable pathways utilized by divergent <i>Rickettsia</i> species for host cell entry. by Kristen E. Rennoll-Bankert (785434)

“…The divergent distal arms of this pathway involve recruitment of factors for activating the actin nucleating complex (Arp2/3), which leads to host actin polymerization, extensive membrane ruffling and filopodia formation, and bacterial internalization in a clathrin and calveolin dependent process. …”

Strategies for constructing the MDV-1 Md5 BAC clone. by Chenyi Bao (7411439)

“…<p>(A) Schematic of the linear MDV-1 Md5 genome and a portion of the unique short region (U_S) containing US10 to US6 ORFs and the location of homologous arms (horizontal dashed line). (B) A linearized transfer vector, pBlue-US2-BAC-RFP, includes homologous arms (US2A and US2B), a loxP-flanked partial sequence of the pBeloBAC11 plasmid, and a selection marker expression cassette (RFP and puromycin). …”

Mechanical Bending and Modulation of Photoactuation Properties in a One-Dimensional Pb(II) Coordination Polymer by Bibhuti Bhusan Rath (5690147)

“…Here, we report a one-dimensional CP comprising PbBr₂ chains with 3-fluoro-4′-styrylpyridine arms showing excellent elasticity and photomechanical properties. …”

Mechanical Bending and Modulation of Photoactuation Properties in a One-Dimensional Pb(II) Coordination Polymer by Bibhuti Bhusan Rath (5690147)

“…Here, we report a one-dimensional CP comprising PbBr₂ chains with 3-fluoro-4′-styrylpyridine arms showing excellent elasticity and photomechanical properties. …”

Mechanical Bending and Modulation of Photoactuation Properties in a One-Dimensional Pb(II) Coordination Polymer by Bibhuti Bhusan Rath (5690147)

“…Here, we report a one-dimensional CP comprising PbBr₂ chains with 3-fluoro-4′-styrylpyridine arms showing excellent elasticity and photomechanical properties. …”