DataSheet_1_PTCH1 and CTNNB1 emerge as pivotal predictors of resistance to neoadjuvant chemotherapy in ER+/HER2- breast cancer.docx door Gulnihal Ozcan (9673713)

“…The dual function of PTCH1 as a multidrug efflux pump and a hedgehog receptor, and the active involvement of CTNNB1 in breast cancer strongly indicate that PTCH1 and CTNNB1 can be potential drug targets to overcome chemoresistance in ER +/HER2- breast cancer patients.…”

Table_1_Source localized infraslow neurofeedback training in people with chronic painful knee osteoarthritis: A randomized, double-blind, sham-controlled feasibility clinical trial... door Jerin Mathew (12220631)

“…Eligible participants attended nine 30-min ISF-NF training sessions involving three cortical regions linked to pain. Feasibility measures were monitored during the trial period. …”

DataSheet_2_Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.csv door Katharine Yu (5688425)

“…Introduction<p>Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes.…”

Timing of Antibiotic Prophylaxis in Elective Caesarean Delivery: A Multi-Center Randomized Controlled Trial and Meta-Analysis door Chuan Zhang (187157)

“…</p><p>Methods</p><p>We conducted a randomized open-label controlled trial with two parallel arms at three hospitals in western China. Participants meeting the inclusion criteria received antibiotics 30-60 minutes before skin incision while others received antibiotics after umbilical cords clamping. …”

Table1_Effectiveness and safety of pelareorep plus chemotherapy versus chemotherapy alone for advanced solid tumors: a meta-analysis.docx door Renxian Xie (17044863)

“…</p><p>Results: There were five studies involving 492 patients included in the study. Combination therapy did not significantly improve clinical outcomes in terms of 1-year OS [RR = 1.02, 95%CI = (0.82–1.25)], 2-year OS [RR = 1.00, 95%CI = (0.67–1.49)], 4-month PFS [RR = 1.00, 95%CI = (0.67–1.49)], 1-year PFS [RR = 0.79, 95%CI = (0.44–1.42)], and ORR [OR = 0.79, 95%CI = (0.49–1.27)] compared to chemotherapy alone, and the subgroup analysis of 2-year OS, 1-year PFS, and ORR based on countries and tumor sites showed similar results. …”

Early Sitting in Ischemic Stroke Patients (SEVEL): A Randomized Controlled Trial door Fanny Herisson (685067)

“…Taking these limitations into account, our results may help guide the development of more effective acute stroke rehabilitation strategies, and the design of future acute stroke trials involving out of bed activities and other mobilization regimens.…”

DataSheet_1_Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.csv door Katharine Yu (5688425)

“…Introduction<p>Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes.…”

DataSheet_1_Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.docx door Katharine Yu (5688425)

“…Introduction<p>Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant tumors is integral for improving patient outcomes.…”

Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines door Lamberto Manzoli (206725)

“…Finally, the rate of serious vaccine-related adverse events was low for all 2009 H1N1 vaccines (3 cases, resolved in 10 days, out of 22826 vaccinated subjects). …”

THR depletion causes failure of chromosomal MNM/SNM release and homolog separation during meiosis I. door Ariane C. Blattner (2633800)

“…Time in minutes is indicated in the lower right corner of the merged images with t = 0 representing the time when chromatin decondensation had progressed to the point where chromosome arms could no longer be resolved individually. In the control (+), the last metaphase I frame was at -9 minutes and the MNM-EGFP dot disappeared within the first 3 minutes of anaphase I. …”

Clamshell Approach for Growing Teratoma Syndrome door Sara Parini (10189308)

“…The left superior pulmonary vein was encircled to ensure its control in case of lung involvement. The underlying left lung was freed of the compressing mass, which was a 2500 g tumor measuring 23 x 16 x 15 cm. …”

Robotic-Assisted Middle Lobe Sleeve Lobectomy for Carcinoid Tumor door Kenji Kawamukai (13863640)

“…</p> <p>Preoperative bronchoscopy confirmed the involvement of the insertion of middle lobe bronchus. …”

Modulated Preparation and Structural Diversification of Zn^II and Cd^II Metal−Organic Frameworks with a Versatile Building Block 5-(4-Pyridyl)-1,3,4-oxadiazole-... door Miao Du (1399054)

“…Four types of binding modes involving monodentate (η-<i>N</i>_oxa), bidentate (μ-<i>N</i>_py,<i>N</i>_oxa, or μ-<i>N</i>_py,<i>S</i>,<i>S</i>) and tridentate (μ-<i>N</i>_py,<i>N</i>_oxa,<i>S</i>) are observed. …”

Data_Sheet_1_The efficacy and safety of different endovascular modalities for infrapopliteal arteries lesions: A network meta-analysis of randomized controlled trials.docx door Julong Guo (12986249)

“…In total, 22 eligible RCTs (44 study arms; 1,348 patients) involving nine endovascular modalities or combinations [balloon angioplasty (BA), drug-coated balloon (DCB), drug-eluting stent (DES), atherectomy device + BA (AD + BA), AD + DCB, balloon-expandable bare metal stent (BMS), self-expanding stent (SES), absorbable metal stents (AMS), and inorganics-coated stent (ICS)] were included. …”

Data set. door Young Joo Park (8911286)

“…One case of HBV-related hepatitis spontaneously resolved after 4 weeks. The rate of SVR for the entire cohort was 87.2%, with no significant difference in this regard among the IFN-based treated, DAA-treated, and DAA-treated after IFN-based treatment failure arms at 82.4%, 88.2%, and 92.3%, respectively. …”

The patient flow-chart. door Young Joo Park (8911286)

“…One case of HBV-related hepatitis spontaneously resolved after 4 weeks. The rate of SVR for the entire cohort was 87.2%, with no significant difference in this regard among the IFN-based treated, DAA-treated, and DAA-treated after IFN-based treatment failure arms at 82.4%, 88.2%, and 92.3%, respectively. …”

CryoEM and 3D image reconstruction of HSV-1 virions. door Marion McElwee (5430029)

“…A close-up view of the portal-vertex shows that the 5-fold symmetry axis is capped by a tiered structure comprising two star-shaped rings of density (the PVAT, f). The arms of the CATC are also angled more towards the 5-fold axis. …”

Image_1_The Coexistence of Genetic Mutations in Thyroid Carcinoma Predicts Histopathological Factors Associated With a Poor Prognosis: A Systematic Review and Network Meta-Analysis... door Ling Zhao (111365)

“…</p>Results<p>27 publications (comprising 9 active intervention arms), involving 8,388 TC patients, were selected. …”

Table_2_The Coexistence of Genetic Mutations in Thyroid Carcinoma Predicts Histopathological Factors Associated With a Poor Prognosis: A Systematic Review and Network Meta-Analysis... door Ling Zhao (111365)

“…</p>Results<p>27 publications (comprising 9 active intervention arms), involving 8,388 TC patients, were selected. …”

Table_1_The Coexistence of Genetic Mutations in Thyroid Carcinoma Predicts Histopathological Factors Associated With a Poor Prognosis: A Systematic Review and Network Meta-Analysis... door Ling Zhao (111365)

“…</p>Results<p>27 publications (comprising 9 active intervention arms), involving 8,388 TC patients, were selected. …”