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3301
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3302
Strategy for the generation of GAD65-tdTomato mice expressing the fluorescent protein tdTomato under control of the GAD65 promoter in GABAergic neurons.
Опубликовано 2015“...The transgene consists of the ORF of tdTomato, a SV40-PolyA site as well as a FRT-flanked neomycin resistance cassette (neo) and was inserted directly after the endogenous ATG using homologous recombination provoked by homology arms (HA) indicated. <b>C:</b> Representation of the modified BAC containing the GAD65-tdTomato transgene after removal of the neomycin resistance cassette using Flp recombination. ...”
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3303
Novel Drosophila Viruses Encode Host-Specific Suppressors of RNAi
Опубликовано 2014“...It has been suggested that an evolutionary ‘arms race’ may occur between rapidly evolving components of the antiviral RNAi pathway of <i>Drosophila</i> and viral genes that antagonize it. ...”
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3304
Evidence for a Common Toolbox Based on Necrotrophy in a Fungal Lineage Spanning Necrotrophs, Biotrophs, Endophytes, Host Generalists and Specialists
Опубликовано 2012“...Consistent with an evolutionary arms race model, positive selection was detected in 5 of 8 genes. ...”
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3305
Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape
Опубликовано 2015“...PRRs directly engaged by pathogen inhibitors often evolve under recurrent bouts of positive selection that have been described as molecular ‘arms races.’ ...”
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3306
Table_1.XLSX
Опубликовано 2018“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”
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3307
Main spider species of medical significance in the Brazilian Amazon.
Опубликовано 2016“...<p><i>Phoneutria fera</i> (A) and <i>Phoneutria reydii</i> (B), commonly known as Brazilian wandering spiders, armed spiders ("armadeiras", as they are known in Brazilian Portuguese), or banana spiders, are a genus of aggressive spiders of the Ctenidae family, with potential medical significance to humans due to their neurotoxic venom. ...”
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3308
Table_3.xlsx
Опубликовано 2018“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”
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3309
Controlled Chaos of Polymorphic Mucins in a Metazoan Parasite <em>(Schistosoma mansoni)</em> Interacting with Its Invertebrate Host <em>(Biomphalaria glabrata)</em>
Опубликовано 2008“...Consequently, the generally accepted arms race hypothesis predicts that molecular diversity and polymorphism also exist in parasites of invertebrates. ...”
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3310
Table_2.XLSX
Опубликовано 2018“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”
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3311
Image_1.PDF
Опубликовано 2018“...<p>The freshwater cyanobacterium Microcystis aeruginosa frequently forms toxic massive blooms and exists in an arms race with its infectious phages in aquatic natural environments, and as a result, has evolved extremely diverse and elaborate antiviral defense systems, including the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated genes (Cas) system. ...”
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3312
Upper lid crease approach for margin rotation in trachomatous cicatricial entropion without external sutures
Опубликовано 2018“...Methods: Surgical description: The main steps of the procedure consisted of exposure of the entire tarsal plate up to the eyelashes followed by tarsotomy through the conjunctiva. A double-armed 6.0 polyglactin suture was then passed through the distal tarsal fragment to the marginal section of the orbicularis oculi muscle. ...”
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3313
(A) Creation of a genetic rescue construct encoding fused with an N-terminal FLAG-tetracysteine tag (4C),
Опубликовано 2011“...(b) PCR product containing left (L) and right (R) homology arms, the 4C tag, and LoxP site (gray triangles) flanked marker. ...”
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3314
A gene expression signature of spontaneous metastasis in a K-ras/p53 mutant mouse model.
Опубликовано 2009“...Log rank test evaluates whether there are significant differences between the two arms. Univariate Cox test evaluates the association of the met signature t-score with patient outcome, treating the coefficient as a continuous variable. ...”
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3315
Background Selection as Baseline for Nucleotide Variation across the <i>Drosophila</i> Genome
Опубликовано 2014“...<div><p>The constant removal of deleterious mutations by natural selection causes a reduction in neutral diversity and efficacy of selection at genetically linked sites (a process called Background Selection, BGS). ...”
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3316
Emergency Anterior Bilateral Thoracotomy
Опубликовано 2024“...</p><p dir="ltr">Blood clots were removed to release the tamponade and the heart was inspected for any lacerations. ...”
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3317
Conditional Chr 13 <i>PRELI</i> gene Targeting.
Опубликовано 2013“...Also indicated are 5′ and 3′ arms of homology, LoxP sites, Flip recombination (Frt) sequences, and PGK-Neo and HSV-Tk selection cassettes; <b>III</b>: Floxed <i>PRELI</i> allele, after Frt-mediated removal of selection cassettes; <b>IV</b>: <i>PRELI</i> deficient allele after CD19-driven Cre recombinase (Cre) cleavage of <i>PRELI</i> exon II. ...”
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3318
Metadata supporting data files in the published article: DNA Methylation Markers Predict Recurrence-free Interval in Triple- Negative Breast Cancer
Опубликовано 2020“...</p> <p><b> </b></p> <p><b>Study approval: </b>All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. ...”
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3319
Endogenous nutrient stores correlate with the CPI-613 response <i>in vitro</i> and <i>in vivo</i>.
Опубликовано 2022“...Note that other cell death studies herein generally involve longer incubation times and, thus, stronger responses....”
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3320
Tsg101 is required for the NiV-C enhancement of budding and efficient release of live NiV.
Опубликовано 2016“...Destabilization of DD-Tsg101 by removal of TMP abrogates the NiV-C enhancement of NiV-M budding. ...”