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Enhanced generation of beta cell precursors and functional insulin-secreting cells from human pluripotent stem cells
Published 2023“…The progenitors and beta cells were extensively characterized for gene expression by immunofluorescence, RT-PCR and functional assay. …”
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Solvent Influence on Absorption Spectra and Tautomeric Equilibria of Symmetric Azomethine‐Functionalized Derivatives: Structural Elucidation and Computational Studies
Published 2023“…<p></p><div> <p>A new series of azomethine-functionalized compounds was synthesized from the condensation of 2-hydroxy-1,3-propanediamine and 2-thienylcarboxaldehydes in the presence of a drying agent. …”
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Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria
Published 2025“…</u> This study focuses on investigating the specific chemical and physical characteristics of Cu-MOFs, investigating their antibacterial capabilities on three representative bacterial strains, and linking their structure to their function. Several techniques for characterization were employed. …”
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Transesterification of Jatropha curcas oil to biodiesel using highly porous sulfonated biochar catalyst: Optimization and characterization dataset
Published 2024“…Here, the activated biochar was functionalized using 4-diazoniobenzenesulfonate to obtain sulfonic acid functionalized activated biochar. …”
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Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant propertiesor radio-therapy resistance
Published 2018“…To expand our molecular characterization of the AI tumorspheres, we sought to define the comprehensive proteomic profile of murine AD and AI neuroblastoma cells. …”
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Novel Loss-of-Function Variants in CDC14A are Associated with Recessive Sensorineural Hearing Loss in Iranian and Pakistani Patients
Published 2020“…The present study functionally characterizes two variants and provides further confirmatory evidence that CDC14A is associated with a rare form of hereditary hearing loss.…”
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Structural interactions of complex proteins with trehalose: mechanisms for improving the multilevel structure and functional properties of lentil-quinoa protein complexes
Published 2024“…The method involved manipulating protein interactions through pH shifting and the addition of trehalose, ultimately enhancing water solubility, digestibility, and the functionality. Fluorescence, ultraviolet, and Fourier-transform spectroscopic techniques were applied to characterize the structural and molecular properties of the trehalose-conjugated lentil-quinoa protein complexes at various concentrations. …”
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Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration
Published 2024“…</u> </p><h3>Objective</h3><p dir="ltr">To characterize functional cellular mechanisms underlying the <u>immune dysregulation</u> phenotype in a <u>proband</u> with a mutated <i><u>TRPM4 </u></i>gene. …”
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Physiochemical characterization and systematic investigation of metals extraction from fly and bottom ashes produced from municipal solid waste
Published 2020“…In this paper, the physicochemical characterizations of the MSW-BA and the MSW-FA were performed, followed by a systematic investigation of metals extraction from MSW-BA and MSW-FA. …”
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Analysis of incidental findings in Qatar genome participants reveals novel functional variants in <i>LMNA</i> and <i>DSP</i>
Published 2022“…Finally, we used a zebrafish knockdown and synthetic human mRNA co-injection assay to functionally characterize two of these novel variants. …”
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Transesterification of <i>Jatropha curcas</i> oil to biodiesel using highly porous sulfonated biochar catalyst: Optimization and characterization dataset
Published 2024“…Here, the activated biochar was functionalized using 4-diazoniobenzenesulfonate to obtain sulfonic acid functionalized activated biochar. …”
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A loss-of-function AGTR1 variant in a critically-ill infant with renal tubular dysgenesis: case presentation and literature review
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">This case highlights the consequence of loss-of-function variants in <i>AGTR1</i> gene leading to RTD, which is characterized by high mortality rate at birth or during the neonatal period. …”
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation
Published 2019“…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …”
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