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141
Table 1_Respiratory microbiome and metabolome features associate disease severity and the need for doxycycline treatment in children with macrolide-resistant Mycoplasma pneumoniae-...
Published 2025“…Introduction<p>Commensal bacterial community along the upper respiratory tract functions against pathogens. The host determinants of Mycoplasma pneumoniae severity should be identified against the increasing threat of macrolide-resistant M. pneumoniae (MRMP) infection. …”
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142
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143
Source data for Fig 2.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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144
Source data for lung metabolomics.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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145
Source data for Fig 5.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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146
Source data for Fig 1.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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147
Flow cytometry gating strategy for MDSC.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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148
Source data for Fig 3.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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149
Source data for Fig 4.
Published 2025“…However, the treatment options are limited due to the continuous evolution of drug-resistant and hypervirulent variants. It is crucial to investigate the mechanisms behind the high mortality rate of hypervirulent <i>Kp</i> (hv<i>Kp</i>) strains to develop new strategies for preventing hv<i>Kp</i> from evading the host’s defenses and improving treatment effectiveness for these fatal infections. …”
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150
Supplementary materials for PhD thesis - "Investigating the importance of the lung epithelium in response to Francisella tularensis"
Published 2025“…The host mechanisms which result in this increased resistance were determined by transcriptional analysis. …”
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151
Table 1_A multi-strain human skin microbiome model provides a testbed for disease modeling.xlsx
Published 2025“…<p>The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. …”
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152
Data Sheet 1_A multi-strain human skin microbiome model provides a testbed for disease modeling.docx
Published 2025“…<p>The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. …”
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153
<b>Data for s</b><b>easonal variations in coral lipids and their significance for energy maintenance in the </b><b>South China Sea</b>
Published 2024“…Based on the δ13C labeling technology, we explored the coupling between lipids and ZD, zooxanthellae autotrophic photosynthesis, and host heterotrophic predation. The results show that ZD and the zooxanthellae photosynthesis intensity decreased in summer. …”
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154
Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of <i>Mycobacterium abscessus</i> in macrophages
Published 2025“…By manipulating host mitochondrial metabolism, we identify a potential host-directed therapeutic strategy against Mab, offering a promising alternative to conventional treatments beleaguered by drug resistance. …”
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155
Table 1_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”
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156
Table 3_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”
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157
Table 4_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”
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158
Table 8_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”
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159
Table 2_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”
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160
Table 6_Absolute abundance calculation enhances the significance of microbiome data in antibiotic treatment studies.xlsx
Published 2025“…Background<p>The intestinal microbiota contributes to the colonization resistance of the gut towards bacterial pathogens. Antibiotic treatment often negatively affects the microbiome composition, rendering the host more susceptible for infections. …”