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therapy resistance » chemotherapy resistance (Expand Search), therapeutic resistance (Expand Search)
decrease therapy » increased therapy (Expand Search), decreases thereby (Expand Search)
therapy resistance » chemotherapy resistance (Expand Search), therapeutic resistance (Expand Search)
decrease therapy » increased therapy (Expand Search), decreases thereby (Expand Search)
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321
Image 2_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.pdf
Published 2025“…However, resistance develops in most ovarian cancer patients. …”
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322
Supplementary file 1_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.docx
Published 2025“…However, resistance develops in most ovarian cancer patients. …”
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323
Image 4_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.jpeg
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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324
Image 3_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.jpeg
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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325
Image 2_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.jpeg
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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326
Image 5_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.jpeg
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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327
Image 1_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.jpeg
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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328
Table 1_The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.docx
Published 2025“…The results showed a significant decrease in fasting blood glucose levels (SMD = −0.79, 95% CI: −1.11 to −0.46). …”
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329
Data Sheet 1_Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1.docx
Published 2025“…<p>Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. …”
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330
Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf
Published 2025“…Introduction<p>The development of therapy resistance and the formation of distant metastases represent clinical unmet needs for patients with advanced prostate cancer (PCa). …”
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331
Table 1_Natural compounds: new therapeutic approach for inhibition of Streptococcus mutans and dental caries.docx
Published 2025“…Studies have also indicated that NCs exhibit significant efficacy in combination therapies. Notably, curcumin has shown promising results in photodynamic therapy against S. mutans. …”
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332
Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx
Published 2025“…Introduction<p>The development of therapy resistance and the formation of distant metastases represent clinical unmet needs for patients with advanced prostate cancer (PCa). …”
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333
Data Sheet 1_Characterization of lysine crotonylation-related lncRNAs for prognostic assessment and immune response in glioma.zip
Published 2025“…Functional assays confirmed that POLR2J4 promotes glioma proliferation, migration, and cisplatin resistance. Mechanistically, POLR2J4 knockdown reduced the expression of drug resistance genes (ABCB1, ABCC1, BCL2), decreased serum levels of IL-6 and TGF-β1, and downregulated TGF-β1 and PD-L1 in tumor tissues, highlighting its role in establishing an immunosuppressive, drug-resistant microenvironment.…”
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334
Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat...
Published 2024“…There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …”
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335
DataSheet1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic...
Published 2024“…There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …”
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336
Data Sheet 1_Increased maternal exercise of moderate intensity improves pregnancy outcomes of gestational diabetes mellitus patients through maintaining the balance of the gut micr...
Published 2025“…Background<p>Exercise therapy can reduce insulin resistance during pregnancy and improve glucose tolerance in women with gestational diabetes mellitus (GDM), leading to better pregnancy outcomes. …”
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337
Data Sheet 2_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.xlsx
Published 2025“…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. Several therapeutic alternatives, including triterpenes, show promising therapeutic potential and reduced toxicity in vitro and in vivo models.…”
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338
Image 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.tif
Published 2025“…Objective<p>Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by progressive β-cell dysfunction and peripheral insulin resistance, leading to dysregulated glucose homeostasis and sustained low-grade inflammation. …”
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339
Data Sheet 1_Multi level effects of Sanghuang Tongxie Formula on type 2 diabetes rats: a comprehensive analysis from intestinal bacteria to metabolome and transcriptome.xlsx
Published 2025“…Objective<p>Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by progressive β-cell dysfunction and peripheral insulin resistance, leading to dysregulated glucose homeostasis and sustained low-grade inflammation. …”
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340
Table 1_Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway.docx
Published 2025“…Ir-1 effectively reduced cell viability and colony formation, arrested the cell cycle at the G2/M phase, inhibited cell migration and invasion, decreased mitochondrial membrane potential, and increased reactive oxygen species (ROS) generation in lung cancer cells. …”