Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”

Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”

Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”

Data Sheet 3_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo... by Xirui Xia (12075476)

“…Objective<p>Mycoplasmas are structurally simple pathogenic microorganisms that can cause a wide range of diseases in humans and animals and conventional antibiotic therapies of fluoroquinolones and tetracyclines are toxic to young children and young animals and macrolide resistance is increasing. …”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Despite significant progress in systemic and immune-based therapies, many patients develop resistance or fail to respond, highlighting the need for new molecular targets. …”

Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do... by Wu Chen (569414)

“…In vivo, small-animal CT detected pulmonary opacities at week 10, concomitant with elevated pulmonary artery flow, increased airway resistance, and heightened circulating levels of TNF-α, VEGF, white blood cells (WBC), and neutrophils. …”

Figure 1; Figure 2; Figure 3; Figure 4; Figure 5; Table 1; Table 2; Table 3; Table 4; SupTable 1; SupTable 2; SupTable 3 by Ramachandran Chelliah (3837415)

“…Smoking also disrupts calciotropic hormone activity (e.g., reduced levels of 25-OH-D and 1,25-(OH)₂-D), leading to decreased intestinal calcium absorption and heightened bone resorption via the RANKL/OPG axis. …”

DataSheet1_Effects of total flavonoids of Rhizoma Drynariae on biochemical indicators of bone metabolism: a systematic review and meta-analysis.DOCX by Wei Li (7081)

“…The tartrate-resistant acid phosphatase (TRACP) decreased significantly (WMD: −1.34; 95% CI: −1.62, −1.06; p < 0.00001). …”

Assessment of mirvetuximab soravtansine immunogenicity in patients with folate receptor alpha-positive ovarian cancer by Fengying Zhu (19818810)

“…Limited data suggest that MIRV ADAs may be associated with decreased efficacy. Due to the very limited number of NAb-positive individuals, no conclusions could be drawn on the effect of NAb on efficacy.…”