Carnegie Trust Vacation Scholarship Poster Competition Entry: Computer-aided Simulation and Visualisation of Metabolic Flux in Diabetic Cardiomyocytes av Nora Novak (13760734)

“…</p> <p><br></p> <p><u>Modelling</u>:</p> <p>I used the iCardio model^[^{<a href="https://pubmed.ncbi.nlm.nih.gov/33691118/" target="_blank">1</a>}^]  for heart muscle cells, which is a collection of 4200 metabolic reactions involving 2890 metabolites. To calculate which of these 4200 reactions occurs at any time I did flux balance analysis. …”

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition av Gui-Chao Kuang (2082499)

“…We described in a previous communication a variant of the popular Cu^I-catalyzed azide−alkyne cycloaddition (AAC) process where 5 mol % of Cu(OAc)₂ in the absence of any added reducing agent is sufficient to enable the reaction. 2-Picolylazide (<b>1</b>) and 2-azidomethylquinoline (<b>2</b>) were found to be by far the most reactive carbon azide substrates that convert to 1,2,3-triazoles in as short as a few minutes under the discovered conditions. …”

DataSheet_1_Identification and validation of IgG N-glycosylation biomarkers of esophageal carcinoma.docx av Huiying Pan (11645463)

“…From the perspective of biological mechanism, IgG fucosylation and mannosylation might involve in the carcinogenesis progression of ESCC, and provide potential therapeutic targets for personalized interventions of cancer progression.…”

Computation Study on Copper-Catalyzed Aerobic Intramolecular Aminooxygenative CC Bond Cleavage to Imides: Different Roles of Mononuclear and Dinuclear Copper Complexes av Yu Li (183836)

“…Instead, a more feasible pathway involving C­(O)–H activation to acyl radical, decarbonylation, and radical capture to LCu­(OAc)­OOR′ was discovered. …”

Data_Sheet_2_The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in... av Irene Fusco (5134250)

“…Although adenosine exerts clear neuroprotective effects through A₁ receptors during ischemia, the use of selective A₁ receptor agonists is hampered by their undesirable peripheral side effects. So far, no evidence is available on the involvement of adenosine A_2B receptors in cerebral ischemia. …”

MicroRNAs as possible indicators of drug sensitivity in breast cancer cell lines av Katharina Uhr (6672539)

“…For this purpose IC₅₀ values of a drug screen involving 34 drugs were associated with miRNA expression data of the same breast cancer cell lines. …”

The neural processing of gestures accompanying figurative speech in a narrative context in patients with schizophrenia. Preliminary results from an fMRI study av Riedl (6892817)

“…Furthermore, patients with schizophrenia tend to misinterpret gestural information. So far, patient studies focused on the integration of speech and gesture on the level of words, sentences or phrases pointing to a dysfunctional involvement of the left inferior frontal gyrus (IFG) in the integration of both modalities (Straube et al. 2013). …”

S1 Dataset - av Mesfin Abebe (12400154)

“…Antenatal depression, with its far-reaching effects on mothers, infants, and children, continues to be a significant public health issue in developing countries such as Ethiopia. …”

Supporting data for "Fracture and Non-linear Response of Biopolymer Network with Dynamic Cross-linkers" av Bingxian Tang (9151802)

“…This file is generated through a series of computational processes that involve the random placement of filaments, periodic boundary rearrangement, and precise calculation of crosslink locations. …”

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition av Gui-Chao Kuang (2082499)

“…We described in a previous communication a variant of the popular Cu^I-catalyzed azide−alkyne cycloaddition (AAC) process where 5 mol % of Cu(OAc)₂ in the absence of any added reducing agent is sufficient to enable the reaction. 2-Picolylazide (<b>1</b>) and 2-azidomethylquinoline (<b>2</b>) were found to be by far the most reactive carbon azide substrates that convert to 1,2,3-triazoles in as short as a few minutes under the discovered conditions. …”

Image_1_The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in Vitr... av Irene Fusco (5134250)

“…Although adenosine exerts clear neuroprotective effects through A₁ receptors during ischemia, the use of selective A₁ receptor agonists is hampered by their undesirable peripheral side effects. So far, no evidence is available on the involvement of adenosine A_2B receptors in cerebral ischemia. …”

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition av Gui-Chao Kuang (2082499)

“…We described in a previous communication a variant of the popular Cu^I-catalyzed azide−alkyne cycloaddition (AAC) process where 5 mol % of Cu(OAc)₂ in the absence of any added reducing agent is sufficient to enable the reaction. 2-Picolylazide (<b>1</b>) and 2-azidomethylquinoline (<b>2</b>) were found to be by far the most reactive carbon azide substrates that convert to 1,2,3-triazoles in as short as a few minutes under the discovered conditions. …”

Image_1_Identification and validation of IgG N-glycosylation biomarkers of esophageal carcinoma.pdf av Huiying Pan (11645463)

“…From the perspective of biological mechanism, IgG fucosylation and mannosylation might involve in the carcinogenesis progression of ESCC, and provide potential therapeutic targets for personalized interventions of cancer progression.…”

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits av Yi-Hsiang Hsu (247531)

“…However, the genetic variants identified so far only explain a small proportion of the heritability for complex traits. …”

Data_Sheet_1_The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in... av Irene Fusco (5134250)

“…Although adenosine exerts clear neuroprotective effects through A₁ receptors during ischemia, the use of selective A₁ receptor agonists is hampered by their undesirable peripheral side effects. So far, no evidence is available on the involvement of adenosine A_2B receptors in cerebral ischemia. …”

Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition av Gui-Chao Kuang (2082499)

“…We described in a previous communication a variant of the popular Cu^I-catalyzed azide−alkyne cycloaddition (AAC) process where 5 mol % of Cu(OAc)₂ in the absence of any added reducing agent is sufficient to enable the reaction. 2-Picolylazide (<b>1</b>) and 2-azidomethylquinoline (<b>2</b>) were found to be by far the most reactive carbon azide substrates that convert to 1,2,3-triazoles in as short as a few minutes under the discovered conditions. …”

31959: A University Online av Lockdown2020 and Beyond Project (17603670)

“…Working in IT but also English I saw the extraordinary efforts that went on during this period from everyone as we moved the entire University to online teaching in the space of a few weeks. This involved boosting IT Infrastructure, sorting our training, but then moving to thinking about proper online teaching and examining where the burden fell to the divisions, departments, libraries, colleagues in the Centre for Teaching and Learning, and many others. …”

Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study av Lyle G. Best (6707183)

“…Multiple single nucleotide polymorphisms (SNP) have been identified which are associated with CRP levels, and Mendelian randomization studies have shown a positive association between SNPs increasing <i>CRP</i> expression and risk of colon cancer (but thus far not CVD). The effects of individual genetic variants often interact with the genetic background of a population and hence we sought to resolve the genetic determinants of serum CRP in a number of American Indian populations.…”

Brp accumulates in <i>srpk79D</i> mutant nerves. av Ervin L. Johnson III (259396)

“…Images in (B, E, and H) and (C, F, and I) were taken at an exposure in which small, infrequent anti-Brp puncta could be resolved in wild-type nerves. This resulted in overexposure of the Brp puncta in srpk79D mutant nerves. …”

Wol GreA through its C-terminal domain interacts with α2ββ′σ subunits of RNAP holoenzyme. av Jeetendra Kumar Nag (315991)

“…Lane M, standard protein marker; Lane 1-3, 10-U of RNAP holoenzyme (α2ββ′σ subunits) were resolved followed by Ponceau staining. (D) Far Western Blotting was performed to determine the specific interaction of Wol GreA and CTD with α2ββ′σ subunits of RNAP. …”