Table_1_Oral arsenic trioxide for treating acute promyelocytic leukaemia: Implications for its worldwide epidemiology and beyond.docx Autor Cyrus R. Kumana (14137284)

“…In contrast to regimens entailing intravenous (IV) ATO, the consequential therapeutic benefits of using oral ATO have been achieved with much less patient inconvenience and quality of life disruption, reduced burdens on health care facilities (hospitalisations and staff involvement), and much enhanced affordability (retail drug & other cost reductions). …”

Image_2_Ocean Acidification-Induced Restructuring of the Plankton Food Web Can Influence the Degradation of Sinking Particles.PDF Autor Paul Stange (344011)

“…This, in turn, could change the composition of sinking organic matter and the efficiency of the biological carbon pump. So far, most OA experiments involving entire plankton communities have been conducted in meso- to eutrophic environments. …”

Table_2_Identification of Spindle and Kinetochore-Associated Family Genes as Therapeutic Targets and Prognostic Biomarkers in Pancreas Ductal Adenocarcinoma Microenvironment.DOCX Autor Yi Liu (36759)

“…Aim<p>The role of spindle and kinetochore-associated (SKA) genes in tumorigenesis and cancer progression has been widely studied. However, so far, the oncogenic involvement of SKA family genes in pancreatic cancer and their prognostic potential remain unknown.…”

Complexity and Variability of Gut Commensal Microbiota in Polyphagous Lepidopteran Larvae Autor Xiaoshu Tang (150593)

“…Recent work suggests that gut microbiota not only provide nutrients, but also involve in the development and maintenance of the host immune system. …”

Image_4_Identification of Spindle and Kinetochore-Associated Family Genes as Therapeutic Targets and Prognostic Biomarkers in Pancreas Ductal Adenocarcinoma Microenvironment.TIF Autor Yi Liu (36759)

“…Aim<p>The role of spindle and kinetochore-associated (SKA) genes in tumorigenesis and cancer progression has been widely studied. However, so far, the oncogenic involvement of SKA family genes in pancreatic cancer and their prognostic potential remain unknown.…”

Drug Design in the Exascale Era: A Perspective from Massively Parallel QM/MM Simulations Autor Bharath Raghavan (3633952)

“…Here, taking two relevant case studies involving the interactions of ligands with rather large enzymes, we showcase the use of our recently developed massively scalable Multiscale Modeling in Computational Chemistry (MiMiC) QM/MM framework (currently using DFT to describe the QM region) to investigate reactions and ligand binding in enzymes of pharmacological relevance. …”

BIBFRAME at the Doorstep Autor Gregory Edwards (17361503)

“…Finally, Lehigh started a year-long pilot with Share-VDE. Our involvement with the SHARE-VDE community and their BIBFRAME catalog will give insight into how our current MARC data works in a BIBFRAME environment that will, among other lessons, help us prepare our MARC records for conversion.…”

Glyceryl Trinitrate for Prevention of Post-ERCP Pancreatitis and Improve the Rate of Cannulation: A Meta-Analysis of Prospective, Randomized, Controlled Trials Autor Jiexia Ding (465378)

“…</p> <p>Results</p><p>Twelve RCTs involving 2649 patients were included. Eleven RCTs compared GTN with placebo for PEP prevention. …”

Video_1_Case Report: Pericardial Effusion Treated With Pericardiectomy Plus Right Atrial Mass Resection: A 2-Year Follow-Up of Cardiac Rosai-Dorfman Disease.MP4 Autor Edoardo Conte (8807522)

“…<p>Background: Rosai-Dorfman disease (RDD) is rare a sinus histiocytosis typically causing lymphadenopathy. Heart involvement is anecdotal, and <30 cases of cardiac RDD (cRDD) have been reported so far.…”

Isolation and Reactivity of Trifluoromethyl Iodonium Salts Autor Johnathan N. Brantley (2072335)

“…These iodoniums have, thus far, eluded isolation and investigation of their innate reactivity (which has encouraged speculation that such species cannot be accessed). …”

The <em>E. coli</em> Effector Protein NleF Is a Caspase Inhibitor Autor Sonja Blasche (389494)

“…We have solved the crystal structure of the caspase-9/NleF complex which shows that NleF uses a novel mode of caspase inhibition, involving the insertion of the carboxy-terminus of NleF into the active site of the protease. …”

Hydrogen Bond Optimization via Molecular Design for the Fabrication of Crystalline Organometallic Wheel-and-Axle Compounds Based on Half-Sandwich Ru(II) Units Autor Alessia Bacchi (639107)

“…The <i>R</i>₂²(8) cyclic pattern is however conserved only in absence of hydrogen bond donor crystallization solvents, which, when present, tend to insert between the COOH group and a Cl–Ru moiety with formation of hydrates or solvates. Far more robust is the supramolecular synthon based on the coupling involving the Ru–NH₂ function as donor and the RuCl₂ group as acceptor, which has been found in five out of seven X-ray structures reported in this work. …”

Genetic Analysis of Fin Development in Zebrafish Identifies Furin and Hemicentin1 as Potential Novel Fraser Syndrome Disease Genes Autor Thomas J. Carney (42485)

“…Our mutant and dose-dependent interaction data suggest a potential involvement of Hmcn1 in Fraser complex-dependent basement membrane anchorage. …”

PROTOCOL for systematic review exploring young people’s perspectives on their role in activism Autor Teagan Riches (19776873)

“…Interest has grown in young people's involvement in activism in recent years due to a reported 'youthquake' in social movements driven by a backdrop of austerity, instability and environmental crisis (Sloam et al. 2022). …”

Estimation of signal and noise distributions. Autor Kendrick Kay (7901603)

“…<p>Here we show results of simulations that assess how well GSN estimates the signal and noise distributions that underlie a set of measurements (code available at <a href="https://osf.io/5uskr" target="_blank">https://osf.io/5uskr</a>). All simulations involve 10 units whose responses are generated as the sum of a sample from a signal distribution and a sample from a noise distribution. …”

Memories of the War - Ronald Parkinson Autor Their Finest Hour Project Team (18604667)

“…</p><p>We were fairly lucky where we lived as far as bombing was concerned there was not Blitz bombing. …”

Reminiscences of a Wartime Teenage Boy Autor Their Finest Hour Project Team (18604667)

“…Several of us from our school were involved. One evening the Americans did not turn up. …”

TCP24 interacts with TGMV AL2 protein. Autor Jacqueline Williams (3493745)

“…<p>Protein-protein (Far Western) gel blots are shown. Samples of 6xHis-TCP24, 6xHis-AL2, and 6xHis-GFP were resolved on 4–20% protein gels and gel blots were overlayed with a soluble fraction from <i>E</i>. …”

Morphological Evolution of Spiders Predicted by Pendulum Mechanics Autor Jordi Moya-Laraño (272202)

“…If the evolution of body shape matches simple pendulum mechanics, animals that move suspending their bodies should evolve relatively longer legs which must confer high moving capabilities.…”

The Crystal Structure of <i>Thermotoga maritima</i> Class III Ribonucleotide Reductase Lacks a Radical Cysteine Pre-Positioned in the Active Site Autor Oskar Aurelius (766026)

“…Mutation of either of two cysteine residues in a disordered loop far from the active site results in inactive enzyme. …”