Image_1_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif od Yunpeng Cao (3609377)

“…Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis.…”

Functional autoantibodies in patients with different forms of dementia od Gerd Wallukat (252625)

“…<div><p>Dementia in general and Alzheimer’s disease in particular is increasingly seen in association with autoimmunity being causatively or supportively involved in the pathogenesis. Besides classic autoantibodies (AABs) present in dementia patients, there is the new autoantibody class called functional autoantibodies, which is directed against G-protein coupled receptors (GPCRs; GPCR-AABs) and are seen as pathogenic players. …”

The Effect of Temperature on the Proteome of Recombinant <i>Pichia pastoris</i> od Martin Dragosits (2388358)

“…The impact of environmental factors on the productivity of yeast cells is poorly investigated so far. Therefore, it is a major concern to improve the understanding of cellular physiology of microbial protein production hosts, including the methylotrophic yeast <i>Pichia pastoris.…”

Video_1_Reconstruction of Intratelencephalic Neurons in the Mouse Secondary Motor Cortex Reveals the Diverse Projection Patterns of Single Neurons.MPG od Hui-Min Lin (3455366)

“…We obtained a neuron with an axonal length of 318.43 mm, which is by far the longest reported axonal length. Our results show that all individual neurons in the MOs, regardless of whether they are located in layer 2/3 or layer 5, display diverse projection patterns and projection strengths, implying that these neurons might be involved in different brain circuits at different intensities. …”

Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis od Sonal (631310)

“…We have used genetic analysis in combination with cellular imaging to show that zebrafish <i>goosepimples/myosin Vb</i> regulates plasma membrane homeostasis and is involved in maintenance of cell size in the periderm, the outermost epidermal layer. …”

Hydrogen Tunneling above Room Temperature Evidenced by Infrared Ion Spectroscopy od Mathias Schäfer (1694968)

“…While hydrogen tunneling at elevated temperatures has, for instance, often been postulated in biochemical processes, spectroscopic proof is thus far limited to cryogenic conditions, under which thermal reactivity is negligible. …”

Video_2_BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo.WMV od Wibke Singer (306957)

“…<p>Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. …”

Data_Sheet_1_A Closed-Loop Toolchain for Neural Network Simulations of Learning Autonomous Agents.PDF od Jakob Jordan (7116161)

“…For scientific questions addressing organisms operating autonomously in their environments, in particular where learning is involved, it is crucial to be able to operate such simulations in a closed-loop fashion. …”

Image_1_A Novel Device of Reaching, Grasping, and Retrieving Task for Head-Fixed Mice.PDF od Satoshi Manita (12532441)

“…To understand the mechanism for controlling this movement at the neural circuit level, it is necessary to observe the activity of individual neurons involved in the movement. For stable electrophysiological or optical recordings of neural activity in a behaving animal, head fixation effectively minimizes motion artifacts. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia od Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”

Image_1_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif od Yunpeng Cao (3609377)

“…Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis.…”

Structural Disorder within <em>Henipavirus</em> Nucleoprotein and Phosphoprotein: From Predictions to Experimental Assessment od Johnny Habchi (245452)

“…In addition, following previous hints establishing a relationship between structural disorder and protein interactivity, the present results suggest that <em>Henipavirus</em> PNT and N_TAIL domains could be involved in manifold protein-protein interactions.</p></div>…”

Cotton <i>GhMKK1</i> Induces the Tolerance of Salt and Drought Stress, and Mediates Defence Responses to Pathogen Infection in Transgenic <i>Nicotiana benthamiana</i> od Wenjing Lu (429886)

“…<div><p>Mitogen-activated protein kinase kinases (MAPKK) mediate a variety of stress responses in plants. So far little is known on the functional role of MAPKKs in cotton. …”

Table_4_Comparative Genomics of Potato Common Scab-Causing Streptomyces spp. Displaying Varying Virulence.DOCX od Cindy Hudec (5527016)

“…Their phylogenomic affiliation was determined, their pan-genome was characterized, and pathogenic determinants involved in their virulence, ranging from weak to aggressive, were compared. 13 out of 14 strains clustered with Streptomyces scabiei, while the last strain clustered with Streptomyces acidiscabies. …”

Multiple yet Controllable Photoswitching in a Single AIEgen System od Peifa Wei (1726861)

“…Most of the systems reported so far possess only one specific function and their nonemissive nature in the aggregated state inevitably limit their applications. …”

Table3_Genome-wide Identification and Analysis of Splicing QTLs in Multiple Sclerosis by RNA-Seq Data.xlsx od Yijie He (6882242)

“…The retained intron AS events are more susceptible to influence of genome variants, and their functions are involved in protein kinase and phosphorylation modification. …”

Spatiotemporal characteristics of near-earth object monitoring from a moon-based station: case from 1962 to 2020 in CNEOS od Guoqiang Chen (270854)

“…Results from the average near-side MBMP VR outperformed the far side GBMP, and other satellites even by 0.4. …”

Nonfluorinated Superomniphobic Surfaces through Shape-Tunable Mushroom-like Polymeric Micropillar Arrays od Hyunchul Kim (249138)

“…Superomniphobic surfaces showing extremely liquid-repellent properties have received a great amount of attention as they can be used in various industrial and biomedical applications. However, so far, the fabrication processes of these materials mostly have involved the coating of perfluorocarbons onto micro- and nanohierarchical structures of these surfaces, which inevitably causes environmental pollution, leading to health concerns. …”

Image_1_Modeling riboflavin transporter deficiency type 2: from iPSC-derived motoneurons to iPSC-derived astrocytes.TIF od Valentina Magliocca (19204177)

“…Riboflavin (Rf) is the precursor of FAD (flavin adenine dinucleotide) and FMN (flavin mononucleotide), which are involved in different redox reactions, including the energetic metabolism processes occurring in mitochondria. …”

Table_1_Placebo and Nocebo Effects Across Symptoms: From Pain to Fatigue, Dyspnea, Nausea, and Itch.pdf od Fabian Wolters (6902117)

“…These effects have thus far been researched most often in pain. It is not yet clear to what extent these findings from pain can be generalized to other somatic symptoms. …”