The <em>Anopheles gambiae</em> Oxidation Resistance 1 (OXR1) Gene Regulates Expression of Enzymes That Detoxify Reactive Oxygen Species by Giovanna Jaramillo-Gutierrez (214939)

“…<div><h3>Background</h3><p>OXR1 is an ancient gene, present in all eukaryotes examined so far that confers protection from oxidative stress by an unknown mechanism. …”

Image_3_Proteomic Identification of Pathways Responsible for the Estradiol Therapeutic Window in AD Animal Models.TIFF by Jie Cui (198388)

“…Our results showed that different signaling pathways were involved in the regulatory effects of estradiol on MAP1A and hemoglobin α. …”

Data_Sheet_1_Bromate reduction by Shewanella oneidensis MR-1 is mediated by dimethylsulfoxide reductase.PDF by Yicheng Wang (810922)

“…In vivo evidence from gene deletion mutants and complemented strains of S. oneidensis MR-1 indicates that MtrB, MtrC, CymA, GspD, and DmsA are involved in bromate reduction, but not NapA, FccA, or SYE4. …”

A Meta Analysis of Pancreatic Microarray Datasets Yields New Targets as Cancer Genes and Biomarkers by Nalin C. W. Goonesekere (553235)

“…We demonstrate that the biological functions ascribed to these genes are clearly associated with PC and metastasis, and that that these genes exhibit a strong link to pathways involved with inflammation and the immune response. …”

Hydrogen Tunneling above Room Temperature Evidenced by Infrared Ion Spectroscopy by Mathias Schäfer (1694968)

“…While hydrogen tunneling at elevated temperatures has, for instance, often been postulated in biochemical processes, spectroscopic proof is thus far limited to cryogenic conditions, under which thermal reactivity is negligible. …”

The Evolutionary Paradox of Tooth Wear: Simply Destruction or Inevitable Adaptation? by Stefano Benazzi (227062)

“…Scholars believe that several factors are involved, but the real dynamics behind this pathology are far from being understood. …”

Multiple yet Controllable Photoswitching in a Single AIEgen System by Peifa Wei (1726861)

“…Most of the systems reported so far possess only one specific function and their nonemissive nature in the aggregated state inevitably limit their applications. …”

Image_6_Neutrophils Encompass a Regulatory Subset Suppressing T Cells in Apparently Healthy Cattle and Mice.tif by Marion Rambault (10199990)

“…For a long time, these first line defenders were considered as microbe killers. However their role is far more complex as cross talk with T cells or dendritic cells have been described for human or mouse neutrophils. …”

Image_3_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif by Yunpeng Cao (3609377)

“…Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis.…”

Image_6_An ex vivo Approach to Study Hormonal Control of Spermatogenesis in the Teleost Oreochromis niloticus.TIF by Michelle Thönnes (9109367)

“…The pituitary gonadotropins, luteinizing hormone, and follicle stimulating hormone, are indispensable for vertebrate spermatogenesis, but we are still far from fully understanding the complex regulatory networks involved in this process. …”

Image_1_Identification of a Potentially Functional circRNA-miRNA-mRNA Regulatory Network in Melanocytes for Investigating Pathogenesis of Vitiligo.tif by Lili Li (42450)

“…Therefore, we found the circRNA-miRNA-mRNA regulatory network are involved in the regulation of numerous melanocyte functions, and these dysregulated circRNAs may closely related to the melanocyte metabolism. …”

Genomes from bacteria associated with the canine oral cavity: A test case for automated genome-based taxonomic assignment by David A. Coil (2226292)

“…We found the results of all three methods to be similar (25 out of the 33 had matching genera), but the GTDB approach required fewer subjective decisions, and required far less labor. The primary differences in the non-identical taxonomic assignments involved cases where GTDB has proposed taxonomic revisions.…”

Table_1_How do compulsory citizenship behaviors affect moral disengagement in organizations? Significance of anger toward the organization during the COVID-19 pandemic.docx by Bora Yildiz (14172939)

“…We are reporting a cross-sectional survey of nurses (n = 294) in private and public hospitals in Istanbul, Turkey. The data analysis involved structural equation modeling and Bayesian mediation.…”

Video_1_BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo.WMV by Wibke Singer (306957)

“…<p>Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. …”

Isotope Labeling-Based Quantitative Proteomics of Developing Seeds of Castor Oil Seed (<i>Ricinus communis</i> L.) by Fábio C. S. Nogueira (1302009)

“…In this study, we used a mass spectrometry-based quantification approach employing isotopic (ICPL) and isobaric (iTRAQ) labeling to investigate the pattern of protein deposition during castor oil seed (<i>Ricinus communis</i> L.) development, including that of proteins involved in fatty acid metabolism, seed-storage proteins (SSPs), toxins, and allergens. …”

Table_3_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.xlsx by Yunpeng Cao (3609377)

“…Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis.…”

Table_2_Does the Rarity of a Flower’s Scent Phenotype in a Deceptive Orchid Explain Its Pollination Success?.XLSX by Herbert Braunschmid (9774314)

“…In deceptive plants, it is assumed that variation in floral scents and other traits involved in pollinator attraction is maintained by negative frequency-dependent selection, i.e., rare phenotypes are more attractive to pollinators and hence, have a higher fitness than common phenotypes. …”

Image_1_Heparanase regulates EMT and cancer stem cell properties in prostate tumors.jpeg by Valentina Masola (477258)

“…However, the impact of EMT and CSCs in prostate cancer progression and patient survival is still far from fully understood. Heparanase (HPSE), the sole mammalian endoglycosidase capable of degrading heparan sulfate (HS), is also involved in prostate cancer progression. …”

Table_1_An ex vivo Approach to Study Hormonal Control of Spermatogenesis in the Teleost Oreochromis niloticus.docx by Michelle Thönnes (9109367)

“…The pituitary gonadotropins, luteinizing hormone, and follicle stimulating hormone, are indispensable for vertebrate spermatogenesis, but we are still far from fully understanding the complex regulatory networks involved in this process. …”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia by Nagore I. Marín-Ramos (1600555)

“…In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. …”