OptiBreech Care IRAS 303028 feasibility data to 21 October 2024 di Shawn Walker (11178093)

“...Sub-group analyses were identified through participant involvement and engagement work as important to support informed decision-making....”

Caspase-1-Dependent and -Independent Cell Death Pathways in <i>Burkholderia pseudomallei</i> Infection of Macrophages di Antje Bast (473327)

“...In the early phase we identified an activation pathway involving caspases-9, -7 and PARP downstream of NLRC4 and caspase-1. ...”

Table1_Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factors.PDF di Dun Liu (674970)

“...Objective<p>Complex chromosome rearrangements (CCR) are rare structural abnormalities involving at least three breakpoints, categorized into three types based on their structure: type A (three-way rearrangements), type B (double two-way translocations), and type C (exceptional CCR). ...”

Data_Sheet_1_CYP17A1–ATP2B1 SNPs and Gene–Gene and Gene–Environment Interactions on Essential Hypertension.docx di Bi-Liu Wei (7538519)

“...Two best significant two-locus models were screened out by GMDR software involving SNP–environment (rs11191548 and BMI ≥ 24 kg/m²) and haplotype–environment (CYP17A1 rs1004467G-rs11191548C and BMI ≥ 24 kg/m²) interactions (p ≤ 0.01). ...”

Supplementary Material for: Proof of Concept Study: Relating Infarct Location to Stroke Disability in the NINDS rt-PA Trial di Phan T.G. (4106239)

“...The model suggested that older age or involvement of either M6 or lentiform nucleus slightly increased the odds of disability. ...”

Data_Sheet_1_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.docx di Alessia Buso (6653861)

“...Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. ...”

Innate-like T cells in children with sickle cell disease di Slimane Allali (341342)

“...These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not investigate the involvement of other innate-like T cell subsets so far....”

Data for Revised Manuscript di Edward Ruthazer (8636664)

“...However, as microglia are well known to ravenously remove debris left behind by apoptotic cells in the developing CNS, such evidence from snapshots of fixed microglia is far from conclusive. Other studies have shown circuit development defects in transgenic animals in which microglial phagocytic activity has been suppressed. ...”

Table_1_Impact of parental lifestyle patterns in the preconception and pregnancy periods on childhood obesity.docx di Marion Lecorguillé (7288424)

“...Introduction<p>High prevalence of overweight and obesity already observed in preschool children suggests the involvement of early-life risk factors. Preconception period and pregnancy are crucial windows for the implementation of child obesity prevention interventions with parental lifestyle factors as relevant targets. ...”

Table_4_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX di Alessia Buso (6653861)

“...Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. ...”

A new otter of giant size, <i>Siamogale melilutra</i> sp. nov. (Lutrinae: Mustelidae: Carnivora), from the latest Miocene Shuitangba site in north-eastern Yunnan, south-western Chi... di Xiaoming Wang (187053)

“...Multiple lineages have developed bunodont dentitions with enlargements of molars, usually for cracking molluscs or other hard foods. Some lineages have evolved badger-like teeth and, as a result, were often confused with melines (Old World badger clade). ...”

Elements: Transformation-Based High-Performance Computing in Dynamic Languages di Andreas Kloeckner (8396844)

“...Correspondingly, modern computing hardware has evolved advanced capabilities for carrying out such computations with high efficiency. ...”

Elements: Transformation-Based High-Performance Computing in Dynamic Languages di Andreas Kloeckner (8396844)

“...Correspondingly, modern computing hardware has evolved advanced capabilities for carrying out such computations with high efficiency. ...”

DataSheet1_High-spectral-resolution Fabry-Pérot interferometers overcome fundamental limitations of present volcanic gas remote sensing techniques.ZIP di Jonas Kuhn (4224637)

“...Here, we present measurements with a shoe-box-size Fabry-Perot interferometer spectrograph (resolving power of ca. 150000), performed in the crater of Nyiragongo volcano. ...”

How I joined the Intelligence Corps di Their Finest Hour Project Team (18604667)

“...</p><p>I was made a Guard Runner, which involved me standing at the main entrance gate with a large stick held behind my back and when a visitor came to the gate I would be assigned to take the visitor to the required destination and another Guard Runner would take my place. ...”

Optimizing Amorphous Molybdenum Sulfide Thin Film Electrocatalysts: Trade-Off between Specific Activity and Microscopic Porosity di Thom R. Harris-Lee (18846535)

“...A novel two-step SECCM protocol is designed to quantitatively determine spatially resolved electrochemical activity and electrochemical surface area (ECSA) within a single, high-throughput measurement. ...”

Data_Sheet_1_Emergent Properties of Microbial Activity in Heterogeneous Soil Microenvironments: Different Research Approaches Are Slowly Converging, Yet Major Challenges Remain.pdf di Philippe C. Baveye (795978)

“...Fortunately, a number of these challenges may be resolved by brand new measuring equipment that will become commercially available in the very near future....”

Amorphous Calcium–Magnesium Carbonate (ACMC) Accelerates Dolomitization at Room Temperature under Abiotic Conditions di German Montes-Hernandez (1876831)

“...The challenge to produce dolomite CaMg­(CO₃)₂ at low temperature (20–35 °C) over laboratory time scales so far has remained unsuccessful, which has led to long-lasting scientific debates in the last two centuries. ...”

Heat map of chromatin interactions and isochores map of mouse chromosome 17. di Kamel Jabbari (582793)

“...Interactions corresponding to GC-poor regions are also seen in domains corresponding to other GC-poor regions even when located far away on the chromosomes, the intensity of such interactions decreasing, however, with distance. ...”

Continent-Wide Decoupling of Y-Chromosomal Genetic Variation from Language and Geography in Native South Americans di Lutz Roewer (401520)

“...For native South Americans, however, such evidence has been lacking so far. Therefore, we examined the relationship between Y-chromosomal genotype on the one hand, and male geographic origin and linguistic affiliation on the other, in the largest study of South American natives to date in terms of sampled individuals and populations. ...”