Presentation_1_CCR4 Antagonist (C021) Administration Diminishes Hypersensitivity and Enhances the Analgesic Potency of Morphine and Buprenorphine in a Mouse Model of Neuropathic Pa... ‌ Joanna Bogacka (9118241)

“…Recent studies have indicated that chemokine signaling pathways are crucial in the development of painful neuropathy; however, the involvement of CC chemokine receptor 4 (CCR4) has not been fully elucidated thus far. …”

Isolation and Reactivity of Trifluoromethyl Iodonium Salts ‌ Johnathan N. Brantley (2072335)

“…These iodoniums have, thus far, eluded isolation and investigation of their innate reactivity (which has encouraged speculation that such species cannot be accessed). …”

Table_1_Decitabine Enhances Vγ9Vδ2 T Cell-Mediated Cytotoxic Effects on Osteosarcoma Cells via the NKG2DL–NKG2D Axis.docx ‌ Zhan Wang (283758)

“…<p>γδ T cell-based immunotherapy for osteosarcoma (OS) has shown limited success thus far. DNA-demethylating agents not only induce tumor cell death but also have an immunomodulatory function. …”

A Celiac Cellular Phenotype, with Altered LPP Sub-Cellular Distribution, Is Inducible in Controls by the Toxic Gliadin Peptide P31-43 ‌ Merlin Nanayakkara (228892)

“…In this study, we examined the hypothesis that a constitutive alteration of the cell shape and the cytoskeleton, involving LPP, occurs in a cell compartment far from the main inflammation site in CD fibroblasts from skin explants. …”

Data_Sheet_1_Pembrolizumab-Induced Isolated Cranial Neuropathy: A Rare Case Report and Review of Literature.PDF ‌ Francesco Bruno (3430520)

“…</p><p>Discussion: Only 16 cases of pembrolizumab-related neuropathies have been described so far. Our case is of particular interest for the isolated involvement of cranial nerves and the prompt response to IVIg.…”

Image_1_Decitabine Enhances Vγ9Vδ2 T Cell-Mediated Cytotoxic Effects on Osteosarcoma Cells via the NKG2DL–NKG2D Axis.jpeg ‌ Zhan Wang (283758)

“…<p>γδ T cell-based immunotherapy for osteosarcoma (OS) has shown limited success thus far. DNA-demethylating agents not only induce tumor cell death but also have an immunomodulatory function. …”

Table 2_Mycobactin and clofazimine activity are negatively correlated in mycobacteria.docx ‌ Martin I. Voskuil (44321)

“…The specific mechanism by which MBT inhibits CFZ lethality remains unclear but may involve, increased iron acquisition, the MmpS5/L5 MBT efflux pump, or the CFZ subcellular localization altered by the redox state and solubility of CFZ. …”

Single Nucleotide Polymorphisms in the Wnt and BMP Pathways and Colorectal Cancer Risk in a Spanish Cohort ‌ Ceres Fernández-Rozadilla (5650399)

“…Candidate-gene studies have so far been one of the basic approaches taken to identify these susceptibility variants. …”

Image_1_Identification of Spindle and Kinetochore-Associated Family Genes as Therapeutic Targets and Prognostic Biomarkers in Pancreas Ductal Adenocarcinoma Microenvironment.TIF ‌ Yi Liu (36759)

“…Aim<p>The role of spindle and kinetochore-associated (SKA) genes in tumorigenesis and cancer progression has been widely studied. However, so far, the oncogenic involvement of SKA family genes in pancreatic cancer and their prognostic potential remain unknown.…”

Lysine120 Interactions with p53 Response Elements can Allosterically Direct p53 Organization ‌ Yongping Pan (31207)

“…Among the major interactions between p53 and its REs involving Lys120, Arg280 and Arg248, the bps interacting with Lys120 vary while the interacting partners of other residues are less so. …”

Image_4_Ocean Acidification-Induced Restructuring of the Plankton Food Web Can Influence the Degradation of Sinking Particles.PDF ‌ Paul Stange (344011)

“…This, in turn, could change the composition of sinking organic matter and the efficiency of the biological carbon pump. So far, most OA experiments involving entire plankton communities have been conducted in meso- to eutrophic environments. …”

Data Sheet 1_Mycobactin and clofazimine activity are negatively correlated in mycobacteria.docx ‌ Martin I. Voskuil (44321)

“…The specific mechanism by which MBT inhibits CFZ lethality remains unclear but may involve, increased iron acquisition, the MmpS5/L5 MBT efflux pump, or the CFZ subcellular localization altered by the redox state and solubility of CFZ. …”

Image_4_Targets and mechanisms of Alpinia oxyphylla Miquel fruits in treating neurodegenerative dementia.TIF ‌ Peng Zeng (2555470)

“…Alzheimer’s disease (AD) is a typical form of neurodegenerative dementia with kidney-essence deficiency in Traditional Chinese Medicine (TCM). So far, there is a lack of systematic studies on the biological basis of tonifying kidney-essence and nourishing intelligence and the corresponding phytochemicals. …”

Video1_Unexpected decrease of full-length prion protein in macaques inoculated with prion-contaminated blood products.MP4 ‌ Nina Jaffré (15415058)

“…In the frame of various experiments, we have previously described that several cynomolgus macaques experimentally exposed to prion-contaminated blood products developed c-BSE/v-CJD, but the vast majority of them developed an unexpected, fatal disease phenotype focused on spinal cord involvement, which does not fulfill the classical diagnostic criteria of v-CJD. …”

Image_5_Ocean Acidification-Induced Restructuring of the Plankton Food Web Can Influence the Degradation of Sinking Particles.PDF ‌ Paul Stange (344011)

“…This, in turn, could change the composition of sinking organic matter and the efficiency of the biological carbon pump. So far, most OA experiments involving entire plankton communities have been conducted in meso- to eutrophic environments. …”

Table_1_Fit, Female or Fifty–Is Cardiac Rehabilitation “Fit” for Purpose for All? A Systematic Review and Meta-Analysis With Meta-Regression.pdf ‌ Martin Smith (51258)

“…</p>Methods<p>MEDLINE, CINAHL, and EMBASE were examined for RCT and cohort studies involving exercise prescription or phase II or III CR following Myocardial Infarction (MI), Percutaneous Coronary Intervention (PCI) and cardiac surgery from January 2010 to February 2021. …”

Table_1_Oral arsenic trioxide for treating acute promyelocytic leukaemia: Implications for its worldwide epidemiology and beyond.docx ‌ Cyrus R. Kumana (14137284)

“…In contrast to regimens entailing intravenous (IV) ATO, the consequential therapeutic benefits of using oral ATO have been achieved with much less patient inconvenience and quality of life disruption, reduced burdens on health care facilities (hospitalisations and staff involvement), and much enhanced affordability (retail drug & other cost reductions). …”

Antimicrobial Use and Veterinary Care among Agro-Pastoralists in Northern Tanzania ‌ Mark A. Caudell (3709282)

“…Studies among small-holders, who own a large percentage of the world’s livestock, are vital for understanding how practices involving AM use might influence resistance. We present a cultural-ecological mixed-methods analysis to explore sectors of veterinary care, loosely regulated AM use, and human exposure to AMs through meat and milk consumption across three rural to peri-urban Tanzanian ethnic groups (N = 415 households). …”

Data_Sheet_2_Deliberate Practice and Proposed Limits on the Effects of Practice on the Acquisition of Expert Performance: Why the Original Definition Matters and Recommendations fo... ‌ K. Anders Ericsson (7547831)

“…The paper concludes with recommendations for how future research on purposeful and deliberate practice can go beyond recording only the duration of practice to measuring the quality of practice involving concentration, analysis, and problem solving to identify conditions for the most effective forms of training.…”

Data_Sheet_3_Cercis: A Non-polyploid Genomic Relic Within the Generally Polyploid Legume Family.zip ‌ Jacob S. Stai (6578882)

“…There is evidence for a genome duplication in the remaining Cercidoideae, which is likely due to allotetraploidy involving hybridization between a Cercis progenitor and a second diploid species that existed at the time of the polyploidy event. …”