Inflammation Aggravates Disease Severity in Marfan Syndrome Patients by Teodora Radonic (132179)

“…Numerous studies reveal an involvement of TGF-β signaling. However, the contribution of tissue inflammation is not addressed so far.…”

Table_5_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

Sero-prevalence and risk factors for hepatitis E virus infection among pregnant women in the Cape Coast Metropolis, Ghana by Dorcas Obiri-Yeboah (844157)

“…</p><p>Methods</p><p>A multicenter (3 selected sites) analytical cross sectional study involving 398 pregnant women in the Cape Coast metropolis was conducted. …”

Table_2_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

OptiBreech Care IRAS 303028 feasibility data to 21 October 2024 by Shawn Walker (11178093)

“…Sub-group analyses were identified through participant involvement and engagement work as important to support informed decision-making.…”

Caspase-1-Dependent and -Independent Cell Death Pathways in <i>Burkholderia pseudomallei</i> Infection of Macrophages by Antje Bast (473327)

“…In the early phase we identified an activation pathway involving caspases-9, -7 and PARP downstream of NLRC4 and caspase-1. …”

Table1_Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factors.PDF by Dun Liu (674970)

“…Objective<p>Complex chromosome rearrangements (CCR) are rare structural abnormalities involving at least three breakpoints, categorized into three types based on their structure: type A (three-way rearrangements), type B (double two-way translocations), and type C (exceptional CCR). …”

Data_Sheet_1_CYP17A1–ATP2B1 SNPs and Gene–Gene and Gene–Environment Interactions on Essential Hypertension.docx by Bi-Liu Wei (7538519)

“…Two best significant two-locus models were screened out by GMDR software involving SNP–environment (rs11191548 and BMI ≥ 24 kg/m²) and haplotype–environment (CYP17A1 rs1004467G-rs11191548C and BMI ≥ 24 kg/m²) interactions (p ≤ 0.01). …”

Supplementary Material for: Proof of Concept Study: Relating Infarct Location to Stroke Disability in the NINDS rt-PA Trial by Phan T.G. (4106239)

“…The model suggested that older age or involvement of either M6 or lentiform nucleus slightly increased the odds of disability. …”

Data_Sheet_1_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.docx by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

Innate-like T cells in children with sickle cell disease by Slimane Allali (341342)

“…These studies provided evidence for the activation of invariant natural killer T (iNKT) cells in adult patients, but did not investigate the involvement of other innate-like T cell subsets so far.…”

Data for Revised Manuscript by Edward Ruthazer (8636664)

“…However, as microglia are well known to ravenously remove debris left behind by apoptotic cells in the developing CNS, such evidence from snapshots of fixed microglia is far from conclusive. Other studies have shown circuit development defects in transgenic animals in which microglial phagocytic activity has been suppressed. …”

Table_1_Impact of parental lifestyle patterns in the preconception and pregnancy periods on childhood obesity.docx by Marion Lecorguillé (7288424)

“…Introduction<p>High prevalence of overweight and obesity already observed in preschool children suggests the involvement of early-life risk factors. Preconception period and pregnancy are crucial windows for the implementation of child obesity prevention interventions with parental lifestyle factors as relevant targets. …”

Table_4_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

How I joined the Intelligence Corps by Their Finest Hour Project Team (18604667)

“…</p><p>I was made a Guard Runner, which involved me standing at the main entrance gate with a large stick held behind my back and when a visitor came to the gate I would be assigned to take the visitor to the required destination and another Guard Runner would take my place. …”

Optimizing Amorphous Molybdenum Sulfide Thin Film Electrocatalysts: Trade-Off between Specific Activity and Microscopic Porosity by Thom R. Harris-Lee (18846535)

“…A novel two-step SECCM protocol is designed to quantitatively determine spatially resolved electrochemical activity and electrochemical surface area (ECSA) within a single, high-throughput measurement. …”

Data_Sheet_1_Emergent Properties of Microbial Activity in Heterogeneous Soil Microenvironments: Different Research Approaches Are Slowly Converging, Yet Major Challenges Remain.pdf by Philippe C. Baveye (795978)

“…Fortunately, a number of these challenges may be resolved by brand new measuring equipment that will become commercially available in the very near future.…”

Amorphous Calcium–Magnesium Carbonate (ACMC) Accelerates Dolomitization at Room Temperature under Abiotic Conditions by German Montes-Hernandez (1876831)

“…The challenge to produce dolomite CaMg­(CO₃)₂ at low temperature (20–35 °C) over laboratory time scales so far has remained unsuccessful, which has led to long-lasting scientific debates in the last two centuries. …”

Heat map of chromatin interactions and isochores map of mouse chromosome 17. by Kamel Jabbari (582793)

“…Interactions corresponding to GC-poor regions are also seen in domains corresponding to other GC-poor regions even when located far away on the chromosomes, the intensity of such interactions decreasing, however, with distance. …”

Continent-Wide Decoupling of Y-Chromosomal Genetic Variation from Language and Geography in Native South Americans by Lutz Roewer (401520)

“…For native South Americans, however, such evidence has been lacking so far. Therefore, we examined the relationship between Y-chromosomal genotype on the one hand, and male geographic origin and linguistic affiliation on the other, in the largest study of South American natives to date in terms of sampled individuals and populations. …”