Image4_Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals.tif по Synne Arstad Bjørnestad (14501651)

“...<p>Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells. Until recently, it was believed that MHC genes and their associated immune components had been conserved since their evolutionary emergence in jawed fish. ...”

Image_1_npc2-Deficient Zebrafish Reproduce Neurological and Inflammatory Symptoms of Niemann-Pick Type C Disease.pdf по Malgorzata Wiweger (51224)

“...The molecular mechanisms that are responsible for NPC disease pathology are far from being understood. The present study generated and characterized a zebrafish mutant that lacks Npc2 protein that may be useful for studies at the organismal, cellular, and molecular levels and both small-scale and high-throughput screens. ...”

Table_3_Comparative transcriptome analysis unveiling reactive oxygen species scavenging system of Sonneratia caseolaris under salinity stress.DOCX по Yan Zhou (6523)

“...This study identified important pathways and candidate genes involved in S. caseolaris salinity tolerance and provided suggestions for further research into the mechanisms of salt tolerance in S. caseolaris....”

Image_4_Comparative transcriptome analysis unveiling reactive oxygen species scavenging system of Sonneratia caseolaris under salinity stress.TIF по Yan Zhou (6523)

“...This study identified important pathways and candidate genes involved in S. caseolaris salinity tolerance and provided suggestions for further research into the mechanisms of salt tolerance in S. caseolaris....”

Image3_Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals.tif по Synne Arstad Bjørnestad (14501651)

“...<p>Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells. Until recently, it was believed that MHC genes and their associated immune components had been conserved since their evolutionary emergence in jawed fish. ...”

Subproteomic signature comparison of <i>in vitro</i> selected fluoroquinolone resistance and ciprofloxacin stress in <i>Salmonella</i> Typhimurium DT104B по Susana Correia (4441537)

“...Although known to be multifactorial, fluoroquinolone resistance is still far from a complete understanding.</p> <p><b>Methods</b>: Subproteome changes between an experimentally selected fluoroquinolone-resistant strain (Se6-M) and its parent strain (Se6), and also in Se6-M under ciprofloxacin (CIP) stress, were evaluated in order to give new insights into the mechanisms involved. ...”

The pathway of LD formation in adipose cells featured by perilipin and vimentin localization. по Hans Heid (413935)

“...<p>Delineated stages of the endogenous LD-formation are schematically presented with additional brief descriptions of individual steps and involved proteins and organelles, respectively. Sequential events in recruiting and combining proteins and organelles are drawn. ...”

Common gene-network signature of different neurological disorders and their potential implications to neuroAIDS по Vidya Sagar (408314)

“...These networks differed in their gene circuits; however, in large, they involved innate immunity signaling pathways, which suggests commonalities in the immunological basis of different neuropathogenesis. ...”

Presentation_2_The Rice DNA-Binding Protein ZBED Controls Stress Regulators and Maintains Disease Resistance After a Mild Drought.pptx по A. Paola Zuluaga (9251225)

“...Moreover, the modification of most disease resistance pathways made so far is detrimental to tolerance to abiotic stresses such as drought. ...”

Table_3_Genome-Scale Profiling and High-Throughput Analyses Unravel the Genetic Basis of Arsenic Content Variation in Rice.XLSX по Sang-Beom Lee (7911803)

“...In particular, the cluster coefficient of japonica (0.428) was larger than that of indica (0.414) in the co-expression network analysis for 23 arsenic genes, and it was confirmed that the distance between genes involved in As induction and detoxification of japonica was far than that of indica. ...”

Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the <em>NFKBIK</em>, <em>PNPLA3</em>, <em>RELA</em>, and <em>SH2B3</em> Loci по Guillaume Paré (84081)

“...Two loci, <em>NFKBIB</em> and <em>RELA</em>, are involved in NFKB signaling pathway; <em>PNPLA3</em> is known for its association with fatty liver disease; and <em>SH3B2</em> has been associated with a multitude of traits and disease including myocardial infarction. ...”

Table_4_Genome-Scale Profiling and High-Throughput Analyses Unravel the Genetic Basis of Arsenic Content Variation in Rice.xlsx по Sang-Beom Lee (7911803)

“...In particular, the cluster coefficient of japonica (0.428) was larger than that of indica (0.414) in the co-expression network analysis for 23 arsenic genes, and it was confirmed that the distance between genes involved in As induction and detoxification of japonica was far than that of indica. ...”

Table_2_Genome-Scale Profiling and High-Throughput Analyses Unravel the Genetic Basis of Arsenic Content Variation in Rice.XLSX по Sang-Beom Lee (7911803)

“...In particular, the cluster coefficient of japonica (0.428) was larger than that of indica (0.414) in the co-expression network analysis for 23 arsenic genes, and it was confirmed that the distance between genes involved in As induction and detoxification of japonica was far than that of indica. ...”

Viruses Associated with Ovarian Degeneration in <em>Apis mellifera</em> L. Queens по Laurent Gauthier (232218)

“...Although our data suggest that DWV and VDV-1 have a role in extreme cases of ovarian degeneration, infection of the ovaries by these viruses does not necessarily result in ovarian degeneration, even at high titres, and additional factors are likely to be involved in this pathology.</p> </div>...”

GABA_A Receptors Containing the α2 Subunit Are Critical for Direction-Selective Inhibition in the Retina по Olivia Nicola Auferkorte (172774)

“...<div><p>Far from being a simple sensor, the retina actively participates in processing visual signals. ...”

MRN1 Implicates Chromatin Remodeling Complexes and Architectural Factors in mRNA Maturation по Louis Düring (135966)

“...<div><p>A functional relationship between chromatin structure and mRNA processing events has been suggested, however, so far only a few involved factors have been characterized. ...”

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling по Peter Reinhardt (327591)

“...Therefore, HTS for neuroprotective compounds requires a cell type that is robustly expandable and able to differentiate into all of the neuronal subtypes involved in disease pathogenesis. Here, we report the derivation and propagation using only small molecules of human neural progenitor cells (small molecule neural precursor cells; smNPCs). smNPCs are robust, exhibit immortal expansion, and do not require cumbersome manual culture and selection steps. ...”

Table2_Atlantic cod (Gadus morhua) MHC I localizes to endolysosomal compartments independently of cytosolic sorting signals.XLSX по Synne Arstad Bjørnestad (14501651)

“...<p>Major histocompatibility complex (MHC) class I and II are crucial for the adaptive immune system because they are involved in peptide presentation to T cells. Until recently, it was believed that MHC genes and their associated immune components had been conserved since their evolutionary emergence in jawed fish. ...”

Image_1_Genome-Scale Profiling and High-Throughput Analyses Unravel the Genetic Basis of Arsenic Content Variation in Rice.jpg по Sang-Beom Lee (7911803)

“...In particular, the cluster coefficient of japonica (0.428) was larger than that of indica (0.414) in the co-expression network analysis for 23 arsenic genes, and it was confirmed that the distance between genes involved in As induction and detoxification of japonica was far than that of indica. ...”

Image_4_Host MicroRNA hsa-miR-494-3p Promotes EV71 Replication by Directly Targeting PTEN.JPEG по Qing Zhao (170569)

“...The overall goal of the study is to get a better insight into whether or not hsa-miR-494-3p is involved in the EV71 infection. We found that the EV71 infection induces cellular apoptosis, and that this process can be counteracted by the over-expression of hsa-miR-494-3p mimics. ...”