New Candidate Targets of AMP-Activated Protein Kinase in Murine Brain Revealed by a Novel Multidimensional Substrate-Screen for Protein Kinases por Roland D. Tuerk (8660466)

“…AMP-activated protein kinase (AMPK) is a heterotrimeric serine/threonine kinase that is involved in the maintenance of energy homeostasis and recovery from metabolic stresses both at the cellular and whole body level. …”

Supplementary Material for: MC4R Dimerization in the Paraventricular Nucleus and GHSR/MC3R Heterodimerization in the Arcuate Nucleus: Is There Relevance for Body Weight Regulation? por Rediger A. (4130758)

“…In this brain region, a variety of G protein-coupled receptors (GPCRs) are expressed that are potentially involved in weight regulation, but so far, the detailed function of most hypothalamic GPCRs is only partially understood. …”

Table_1_The Broad Spectrum of LMNA Cardiac Diseases: From Molecular Mechanisms to Clinical Phenotype.docx por Silvia Crasto (9082739)

“…Indeed, the severity and progression of the disease have marked interindividual variability, even amongst members of the same family. Studies conducted so far have described Lamin A/C proteins involved in diverse biological processes, that span from a structural role in the nucleus to the regulation of response to mechanical stress and gene expression, proposing various mechanistic hypotheses. …”

Time trend in hospitalizations from motor vehicle accidents in the city of São Paulo, Brazil, 2000-2019 por Gleice Margarete de Souza Conceição (10372824)

“…The most frequent type of accident involved motorcyclists (42.8%), followed by run-over pedestrians (33.7%). …”

Image_5_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Image_4_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Data_Sheet_1_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.PDF por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Data_Sheet_1_Quorum Sensing Regulates Bacterial Processes That Play a Major Role in Marine Biogeochemical Cycles.xlsx por Marion Urvoy (11822393)

“…<p>Bacteria play a crucial role in marine biogeochemistry by releasing, consuming and transforming organic matter. Far from being isolated entities, bacteria are involved in numerous cell–cell interactions. …”

BTG Interacts with Retinoblastoma to Control Cell Fate in <em>Dictyostelium</em> por Daniele Conte (251859)

“…The latter two processes overlap: genes involved in the cessation of growth may also be important in triggering differentiation. …”

Data_Sheet_1_Biochemical and genetic examination of two aminotransferases from the hyperthermophilic archaeon Thermococcus kodakarensis.PDF por Yu Su (460400)

“…Multiple aminotransferases, along with glutamate dehydrogenase, are presumed to be involved in the catabolic conversion of amino acids. …”

Image_1_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Image_8_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Image_7_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Image_6_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Image_3_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

Characterization of <em>Leishmania donovani</em> MCM4: Expression Patterns and Interaction with PCNA por Neha Minocha (211709)

“…<div><p>Events leading to origin firing and fork elongation in eukaryotes involve several proteins which are mostly conserved across the various eukaryotic species. …”

Image_2_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG por Franziska Handel (9440429)

“…<p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6). …”

A new paramutation-like example at the <i>Delta</i> gene of <i>Drosophila</i> por Maria Capovilla (220512)

“…Distinct from paramutation events so far described in <i>Drosophila</i>, here we deal with a dominant effect on a single gene involving variable hereditary signals.…”

Molecular Epidemiology of <i>Brucella abortus</i> in Northern Ireland—1991 to 2012 por Adrian Allen (624953)

“…Bovine brucellosis caused by <i>Brucella abortus</i> has far reaching animal health and economic impacts at both the local and national levels. …”

A grid-aware emergency response model for natural disasters. Appendices 2 - 5. por Eleana Asimakopoulou (7182590)

“…The approach adopted in the research involved literature reviews, case studies, face-toface structured interviews with emergency management stakeholders and leT experts, model development using Soft Systems Methodology (SSM) linked to Information Systems Development Methodologies (lSDMs), and finally, one-to-one evaluation exercises. ease studies and interviews involving two member states of the European Union were carried out to investigate current practices and to highlight the limitations that emergency management stakeholders face during response operations. …”