NADPH-Cytochrome P450 Reductase: Molecular Cloning and Functional Characterization of Two Paralogs from <em>Withania somnifera</em> (L.) Dunal Bằng Satiander Rana (380737)

“…Although its chemical profile and pharmacological activities have been studied extensively during the last two decades, limited attempts have been made to decipher the biosynthetic route and identification of key regulatory genes involved in withanolide biosynthesis. Cytochrome P450 reductase is the most imperative redox partner of multiple P450s involved in primary and secondary metabolite biosynthesis. …”

DataSheet2_Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice.xlsx Bằng Aiwen Pi (10268048)

“…However, the molecular mechanisms involved in alcohol abstinence-improved recovery from alcoholic fatty liver remain unclear. …”

Image1_Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice.TIF Bằng Aiwen Pi (10268048)

“…However, the molecular mechanisms involved in alcohol abstinence-improved recovery from alcoholic fatty liver remain unclear. …”

Image_1_Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome.tif Bằng Xiaoping Hong (1722382)

“…The immune cell subsets and susceptibility genes involved in the pathogenesis of pSS were analyzed. …”

Proteome Analysis of Plastids from Developing Seeds of <i>Jatropha curcas</i> L. Bằng Camila B. Pinheiro (1892326)

“…Proteins extracted from the plastids were digested with trypsin, and the peptides were applied to an EASY-nano LC system coupled inline to an ESI-LTQ-Orbitrap Velos mass spectrometer, and this led to the identification of 1103 proteins representing 804 protein groups, of which 923 proteins were considered as true identifications, and this considerably expands the repertoire of <i>J. curcas</i> proteins identified so far. Of the identified proteins, only five are encoded in the plastid genome, and none of them are involved in photosynthesis, evidentiating the nonphotosynthetic nature of the isolated plastids. …”

Image_2_Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome.tif Bằng Xiaoping Hong (1722382)

“…The immune cell subsets and susceptibility genes involved in the pathogenesis of pSS were analyzed. …”

Data_Sheet_1_Adaptation of Temperate Seagrass to Arctic Light Relies on Seasonal Acclimatization of Carbon Capture and Metabolism.docx Bằng Alexander Jueterbock (428770)

“…Although light-reactions, and genes involved in carbon capture and carbon storage were upregulated in summer, enzymes involved in CO₂ fixation and chlorophyll-synthesis were upregulated in winter, suggesting that winter metabolism relies not only on stored energy resources but also on active use of dim light conditions. …”

Image_3_Single-Cell RNA Sequencing Reveals the Expansion of Cytotoxic CD4+ T Lymphocytes and a Landscape of Immune Cells in Primary Sjögren’s Syndrome.tif Bằng Xiaoping Hong (1722382)

“…The immune cell subsets and susceptibility genes involved in the pathogenesis of pSS were analyzed. …”

Image_1_Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons.TIFF Bằng Valentina Di Maria (581955)

“…Several of these approaches have been successfully used in neurons in vitro and in vivo, but have not been so far extensively applied for the overexpression of genes involved in synaptic transmission. …”

Data_Sheet_1_Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons.docx Bằng Valentina Di Maria (581955)

“…Several of these approaches have been successfully used in neurons in vitro and in vivo, but have not been so far extensively applied for the overexpression of genes involved in synaptic transmission. …”

Proteome Analysis of Plastids from Developing Seeds of <i>Jatropha curcas</i> L. Bằng Camila B. Pinheiro (1892326)

“…Proteins extracted from the plastids were digested with trypsin, and the peptides were applied to an EASY-nano LC system coupled inline to an ESI-LTQ-Orbitrap Velos mass spectrometer, and this led to the identification of 1103 proteins representing 804 protein groups, of which 923 proteins were considered as true identifications, and this considerably expands the repertoire of <i>J. curcas</i> proteins identified so far. Of the identified proteins, only five are encoded in the plastid genome, and none of them are involved in photosynthesis, evidentiating the nonphotosynthetic nature of the isolated plastids. …”

Image1_Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice.TIF Bằng Aiwen Pi (10268048)

“…However, the molecular mechanisms involved in alcohol abstinence-improved recovery from alcoholic fatty liver remain unclear. …”

Supplementary Material for: Early-Life Stress Perturbs Key Cellular Programs in the Developing Mouse Hippocampus Bằng Wei L. (4146940)

“…However, very little work has been done so far to characterize the effects of ELS on hippocampal development in the mouse. …”

Image_2_Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons.TIFF Bằng Valentina Di Maria (581955)

“…Several of these approaches have been successfully used in neurons in vitro and in vivo, but have not been so far extensively applied for the overexpression of genes involved in synaptic transmission. …”

DataSheet1_Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice.docx Bằng Aiwen Pi (10268048)

“…However, the molecular mechanisms involved in alcohol abstinence-improved recovery from alcoholic fatty liver remain unclear. …”

Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos Bằng Zhilian Hu (777443)

“…DDB1 is also a component of the CUL4 E3 ligase complex involved in a broad spectrum of cellular processes by targeted ubiquitination of key regulators. …”

Data_Sheet_1_Cognitive, Language, and Behavioral Outcomes in Children With Autism Spectrum Disorders Exposed to Early Comprehensive Treatment Models: A Meta-Analysis and Meta-Regre... Bằng Bijun Shi (4882528)

“…However, most extant research involves small, non-randomized studies, preventing definitive conclusions from being drawn. …”

Image_2_Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons.TIF Bằng Livia Rosa-Fernandes (5047643)

“…Nonetheless, signaling mechanisms that promote the disease outcome are far from being understood, affecting the development of suitable therapeutics. …”

Image_1_Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons.TIF Bằng Livia Rosa-Fernandes (5047643)

“…Nonetheless, signaling mechanisms that promote the disease outcome are far from being understood, affecting the development of suitable therapeutics. …”

Table_1_Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons.XLSX Bằng Livia Rosa-Fernandes (5047643)

“…Nonetheless, signaling mechanisms that promote the disease outcome are far from being understood, affecting the development of suitable therapeutics. …”