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2421
Transcriptome Analysis Suggests That Starch Synthesis May Proceed via Multiple Metabolic Routes in High Yielding Potato Cultivars
منشور في 2012"…</p> <h3>Principal Finding</h3><p>Potato tubers of the high yielding cv Kuras had low gene expression of plastidial phophoglucomutase (PGM) and normal levels of transcripts for other enzymes involved in starch metabolism in comparison with medium and low yielding cultivars as determined by DeepSAGE transcriptome profiling. …"
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2422
Table_4_Epilithic Microbial Community Functionality in Deep Oligotrophic Continental Bedrock.XLSX
منشور في 2022"…<p>The deep terrestrial biosphere hosts vast sessile rock surface communities and biofilms, but thus far, mostly planktic communities have been studied. …"
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2423
Targeting the Conformational Transitions of MDM2 and MDMX: Insights into Dissimilarities and Similarities of p53 Recognition
منشور في 2008"…MDM2 and MDMX are oncogenic homologue proteins that regulate the activity and stability of p53, a tumor suppressor protein involved in more than 50% of human cancers. While the large body of experiments so far accumulated has validated MDM2 as a therapeutically important target for the development of anticancer drugs, it is only recently that MDMX has also become an attractive target for the treatment of tumor cells expressing wild type p53. …"
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2424
The secretin-pilotin complex.
منشور في 2012"…(E) Close up showing the hydrophobic nature of the complementary side chains involved in forming the complex.</p>…"
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2425
Table_1_Epilithic Microbial Community Functionality in Deep Oligotrophic Continental Bedrock.XLSX
منشور في 2022"…<p>The deep terrestrial biosphere hosts vast sessile rock surface communities and biofilms, but thus far, mostly planktic communities have been studied. …"
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2426
Table_2_Quorum Sensing-Mediated and Growth Phase-Dependent Regulation of Metabolic Pathways in Hafnia alvei H4.XLS
منشور في 2021"…<p>Quorum sensing (QS) is a widespread regulatory mechanism in bacteria used to coordinate target gene expression with cell density. Thus far, little is known about the regulatory relationship between QS and cell density in terms of metabolic pathways in Hafnia alvei H4. …"
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2427
Therapeutic Assessment of Vulvar Squamous Intraepithelial Lesions with CO2 Laser Vaporization in Immunosuppressed Patients
منشور في 2018"…Results Patients bearing vulvar high-grade squamous intraepithelial lesion and immunosuppressed (serumpositive forhumanimmunodeficiency virus [HIV] or with solid organs transplantation) have shown a higher level of persistence of lesions and a higher chance of having other areas of the female lower genital tract involved. Conclusion While the CO2 laser vaporization is the most conservative method for the treatment of vulvar high-grade intraepithelial lesions, it is far frombeing the ideal method, dueto the intrinsic infection features considered. …"
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2428
Data_Sheet_1_BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo.docx
منشور في 2018"…<p>Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. …"
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2429
Table1.XLSX
منشور في 2018"…<p>Galaxea fascicularis, a stony coral belonging to family Oculinidae, is widely distributed in Red Sea, the Gulf of Aden and large areas of the Indo-Pacific oceans. So far there is a lack of gene expression knowledge concerning this massive coral. …"
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2430
Image_4_An ex vivo Approach to Study Hormonal Control of Spermatogenesis in the Teleost Oreochromis niloticus.TIF
منشور في 2020"…The pituitary gonadotropins, luteinizing hormone, and follicle stimulating hormone, are indispensable for vertebrate spermatogenesis, but we are still far from fully understanding the complex regulatory networks involved in this process. …"
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2431
<i>Meioc</i> maintains an extended meiotic prophase I in mice
منشور في 2017"…Mouse germ cells lacking <i>Meioc</i> initiate meiosis: they undergo pre-meiotic DNA replication, they express proteins involved in synapsis and recombination, and a subset of cells progress as far as the zygotene stage of prophase I. …"
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2432
Image_1_Proteomic Identification of Pathways Responsible for the Estradiol Therapeutic Window in AD Animal Models.TIFF
منشور في 2019"…Our results showed that different signaling pathways were involved in the regulatory effects of estradiol on MAP1A and hemoglobin α. …"
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2433
Identification of New Mechanisms of Cellular Response to Chemotherapy by Tracking Changes in Post-Translational Modifications by Ubiquitin and Ubiquitin-Like Proteins
منشور في 2014"…Gemcitabine treatment altered the PTM profile of proteins involved in various biological functions, some known cancer associated genes, many potentially cancer-associated genes, and several cancer-signaling networks, including canonical and noncanonical WNT and PI3K/Akt/MTOR pathways. …"
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2434
Image_8_An ex vivo Approach to Study Hormonal Control of Spermatogenesis in the Teleost Oreochromis niloticus.TIF
منشور في 2020"…The pituitary gonadotropins, luteinizing hormone, and follicle stimulating hormone, are indispensable for vertebrate spermatogenesis, but we are still far from fully understanding the complex regulatory networks involved in this process. …"
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2435
Supplementary Material for: Primary ovarian failure in addition to classical clinical features of Coats Plus Syndrome in a female carrying two truncating variants of CTC1
منشور في 2021"…Coats plus syndrome is an autosomal recessive multisystemic and pleiotropic disorder affecting the eyes, brain, bone, and gastrointestinal tract, usually caused by compound heterozygous variants of the Conserved Telomere maintenance Component 1 gene (CTC1), involved in telomere homeostasis and replication. So far, most reported patients are compound heterozygous for a truncating mutation and a missense variant. …"
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2436
Taking Root: Enduring Effect of Rhizosphere Bacterial Colonization in Mangroves
منشور في 2010"…Due to the sheer abundance of roots in mangrove habitat, such an effect can have an important impact on the maintenance of bacterial guilds involved in nutrient cycling and other key ecosystem functions. …"
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2437
Cell Surface Proteome Analysis of Human-Hosted <i>Trypanosoma cruzi</i> Life Stages
منشور في 2014"…</i> It remains a challenging health issue in Latin America, where it is endemic, and so far there is no immunoprophylatic vaccine or satisfactory chemotherapic treatment for its chronic stage. …"
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2438
Table_2_An ex vivo Approach to Study Hormonal Control of Spermatogenesis in the Teleost Oreochromis niloticus.docx
منشور في 2020"…The pituitary gonadotropins, luteinizing hormone, and follicle stimulating hormone, are indispensable for vertebrate spermatogenesis, but we are still far from fully understanding the complex regulatory networks involved in this process. …"
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2439
Public opinions of Biodiversity Net Gain in England
منشور في 2025"…</li><li>To what extent do the public trust the organisations involved in BNG?</li><li>What is the public’s opinion of BNG as an approach? …"
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2440
Table_3_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.xlsx
منشور في 2020"…Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis.…"