Presentation_1_A triphosphate tunnel metalloenzyme from pear (PbrTTM1) moonlights as an adenylate cyclase.pdf حسب Ye Yuan (531126)

"…Inside the tunnel, the charged residues were possibly involved in the catalytic process by coordinating with divalent cation and ligand. …"

Targeting the Conformational Transitions of MDM2 and MDMX: Insights into Dissimilarities and Similarities of p53 Recognition حسب Antonio Macchiarulo (182335)

"…MDM2 and MDMX are oncogenic homologue proteins that regulate the activity and stability of p53, a tumor suppressor protein involved in more than 50% of human cancers. While the large body of experiments so far accumulated has validated MDM2 as a therapeutically important target for the development of anticancer drugs, it is only recently that MDMX has also become an attractive target for the treatment of tumor cells expressing wild type p53. …"

Table_3_Epilithic Microbial Community Functionality in Deep Oligotrophic Continental Bedrock.XLSX حسب Maija Nuppunen-Puputti (12162836)

"…<p>The deep terrestrial biosphere hosts vast sessile rock surface communities and biofilms, but thus far, mostly planktic communities have been studied. …"

Image_3_Integrated Microbiome and Metabolome Analysis Reveals a Positive Change in the Intestinal Environment of Myostatin Edited Large White Pigs.JPEG حسب Yangli Pei (727447)

"…While both genotype and microbial composition are known to affect the host phenotype, so far there has been no systematic study to detect the changes in the intestinal microbial composition and metabolome of MSTN single copy mutant pigs. …"

Image_1_Meta-Analysis Reveals Consistent Bacterial Responses to Land Use Change Across the Tropics.JPEG حسب Ian A. B. Petersen (7369286)

"…<p>Bacterial communities are a major component of global diversity and are intimately involved in most terrestrial biogeochemical processes. …"

DataSheet_1_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.pdf حسب Hai Fang (160549)

"…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …"

Photoionization Cross Section of the NH₂ Free Radical in the 11.1–15.7 eV Energy Range حسب Oliver J. Harper (10498428)

"…The NH₂ radical is a key component in many astrophysical environments, both in its neutral and cationic forms, being involved in the formation of complex N-bearing species. …"

Image_5_Neutrophils Encompass a Regulatory Subset Suppressing T Cells in Apparently Healthy Cattle and Mice.tif حسب Marion Rambault (10199990)

"…For a long time, these first line defenders were considered as microbe killers. However their role is far more complex as cross talk with T cells or dendritic cells have been described for human or mouse neutrophils. …"

Curcumin ameliorates aluminum oxide nanoparticle-induced memory deficit by regulating the hippocampal p38 signaling pathway in mice حسب Roksana Soukhaklari (17700986)

"…Recent evidence indicates that the toxicity of Al nanoparticle (Al-NP) is far greater than Al itself due to its particle size. …"

Table3.XLSX حسب Jing Hou (18672)

"…<p>Galaxea fascicularis, a stony coral belonging to family Oculinidae, is widely distributed in Red Sea, the Gulf of Aden and large areas of the Indo-Pacific oceans. So far there is a lack of gene expression knowledge concerning this massive coral. …"

Isotope Labeling-Based Quantitative Proteomics of Developing Seeds of Castor Oil Seed (<i>Ricinus communis</i> L.) حسب Fábio C. S. Nogueira (1302009)

"…In this study, we used a mass spectrometry-based quantification approach employing isotopic (ICPL) and isobaric (iTRAQ) labeling to investigate the pattern of protein deposition during castor oil seed (<i>Ricinus communis</i> L.) development, including that of proteins involved in fatty acid metabolism, seed-storage proteins (SSPs), toxins, and allergens. …"

Data_Sheet_2_Metabolic Plasticity of Gilthead Seabream Under Different Stressors: Analysis of the Stress Responsive Hepatic Proteome and Gene Expression.pdf حسب Cláudia Raposo de Magalhães (10749099)

"…Nevertheless, the molecular response to a prolonged stress can be more heterogeneous and far more complex to interpret than that to an acute stress. …"

Image_1_Myeloid CD169/Siglec1: An immunoregulatory biomarker in viral disease.JPEG حسب Silva Herzog (13849183)

"…In this review, we describe the role of CD169 as a potentially novel diagnostic biomarker for respiratory viral infection by evaluating its strengths and weaknesses and considering host factors that are involved in pathogenesis of virus infection. Finally, this brief review aims to point out shortcomings of available evidence, thus, guiding future work revolving the topic.…"

Image_2_Integrated Microbiome and Metabolome Analysis Reveals a Positive Change in the Intestinal Environment of Myostatin Edited Large White Pigs.JPEG حسب Yangli Pei (727447)

"…While both genotype and microbial composition are known to affect the host phenotype, so far there has been no systematic study to detect the changes in the intestinal microbial composition and metabolome of MSTN single copy mutant pigs. …"

Video_1_A Novel Device of Reaching, Grasping, and Retrieving Task for Head-Fixed Mice.MP4 حسب Satoshi Manita (12532441)

"…To understand the mechanism for controlling this movement at the neural circuit level, it is necessary to observe the activity of individual neurons involved in the movement. For stable electrophysiological or optical recordings of neural activity in a behaving animal, head fixation effectively minimizes motion artifacts. …"

Nonfluorinated Superomniphobic Surfaces through Shape-Tunable Mushroom-like Polymeric Micropillar Arrays حسب Hyunchul Kim (249138)

"…Superomniphobic surfaces showing extremely liquid-repellent properties have received a great amount of attention as they can be used in various industrial and biomedical applications. However, so far, the fabrication processes of these materials mostly have involved the coating of perfluorocarbons onto micro- and nanohierarchical structures of these surfaces, which inevitably causes environmental pollution, leading to health concerns. …"

Table1_Functional analysis of differently expressed ferroptosis-related genes in patients with mitral valve prolapse.XLSX حسب Hui Xie (195238)

"…Notably, these genes are primarily involved in the extracellular region and p53 signaling pathway.…"

Isotope Labeling-Based Quantitative Proteomics of Developing Seeds of Castor Oil Seed (<i>Ricinus communis</i> L.) حسب Fábio C. S. Nogueira (1302009)

"…In this study, we used a mass spectrometry-based quantification approach employing isotopic (ICPL) and isobaric (iTRAQ) labeling to investigate the pattern of protein deposition during castor oil seed (<i>Ricinus communis</i> L.) development, including that of proteins involved in fatty acid metabolism, seed-storage proteins (SSPs), toxins, and allergens. …"

Table4.XLSX حسب Jing Hou (18672)

"…<p>Galaxea fascicularis, a stony coral belonging to family Oculinidae, is widely distributed in Red Sea, the Gulf of Aden and large areas of the Indo-Pacific oceans. So far there is a lack of gene expression knowledge concerning this massive coral. …"

Targeting the Conformational Transitions of MDM2 and MDMX: Insights into Dissimilarities and Similarities of p53 Recognition حسب Antonio Macchiarulo (182335)

"…MDM2 and MDMX are oncogenic homologue proteins that regulate the activity and stability of p53, a tumor suppressor protein involved in more than 50% of human cancers. While the large body of experiments so far accumulated has validated MDM2 as a therapeutically important target for the development of anticancer drugs, it is only recently that MDMX has also become an attractive target for the treatment of tumor cells expressing wild type p53. …"