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1861
Data_Sheet_2_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.xlsx
منشور في 2019"…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …"
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1862
Revealing a Two-Loop Transcriptional Feedback Mechanism in the Cyanobacterial Circadian Clock
منشور في 2013"…<div><p>Molecular genetic studies in the circadian model organism <i>Synechococcus</i> have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription. …"
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1863
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
منشور في 2011"…Some of these processes are centrally involved in regulation of cellular responses to hypoxia. …"
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1864
Video_6_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4
منشور في 2021"…These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood.…"
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1865
DataSheet1_A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities.docx
منشور في 2022"…The condition is caused by a homozygous or compound heterozygous mutation in fatty acid 2 hydroxylase (FA2H), whose encoded protein synthesizes 2-hydroxysphingolipids and 2-hydroxyglycosphingolipids and is therefore involved in sphingolipid metabolism. A few FAHN model organisms have already been established and give the first insight into symptomatic effects. …"
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1866
Data_Sheet_13_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.PDF
منشور في 2020"…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …"
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1867
Video_1_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4
منشور في 2021"…These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood.…"
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1868
Data_Sheet_8_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA
منشور في 2020"…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …"
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1869
Table_2_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx
منشور في 2021"…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …"
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1870
Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity
منشور في 2017"…<p>The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far. …"
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1871
Image_6_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.JPEG
منشور في 2019"…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …"
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1872
Table_1_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX
منشور في 2020"…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …"
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1873
Table_6_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx
منشور في 2021"…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …"
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1874
Table_12_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX
منشور في 2020"…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …"
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1875
Receptor Tyrosine Kinase (RTK) Mediated Tyrosine Phosphor-Proteome from Drosophila S2 (ErbB1) Cells Reveals Novel Signaling Networks
منشور في 2008"…Tyrosine phosphorylation events mediated by aberrant activation of Receptor Tyrosine Kinase (RTK) pathways have been proven to be involved in the development of several diseases including cancer. …"
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1876
Design and Pharmacological Characterization of α<sub>4</sub>β<sub>1</sub> Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Anta...
منشور في 2023"…α<sub>4</sub>β<sub>1</sub> integrin is a cell adhesion receptor deeply involved in the migration and accumulation of leukocytes. …"
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1877
DataSheet1_Virtual Screening of Drug-Like Compounds as Potential Inhibitors of the Dengue Virus NS5 Protein.pdf
منشور في 2022"…Annually, there are about 400 million new cases of dengue worldwide, and so far there is no specific treatment against this disease. …"
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1878
Prevalence of major virulence factors and resistance determinants in 317 SAB isolates.
منشور في 2013"…Fusidic acid resistance (<i>far1</i>), surface protein involved in biofilm formation (<i>bap</i>) genes and capsule type 1 genes (capH1/I1/J1/K1) were not detected.…"
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1879
Table_3_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX
منشور في 2020"…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …"
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1880
Design and Pharmacological Characterization of α<sub>4</sub>β<sub>1</sub> Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Anta...
منشور في 2023"…α<sub>4</sub>β<sub>1</sub> integrin is a cell adhesion receptor deeply involved in the migration and accumulation of leukocytes. …"