A Supervised Molecular Dynamics Approach to Unbiased Ligand–Protein Unbinding by Giuseppe Deganutti (2609257)

“…However, a known limitation of MD is that the time scales are usually far from those involved in ligand–receptor unbinding events. …”

Transcriptomic profiling of the mussel <i>Mytilus trossulus</i> with a special emphasis on integrin-like genes during development by Mariia A. Maiorova (6817130)

“…Our transcriptome dataset contributes to the genetic databases of non-model animals such as bivalves and represents the first characterization of expressed sequences during early development of the mollusc <i>M. trossulus</i> from the Sea of Japan including the identification of candidate genes involved in cell adhesion.</p>…”

Systematic Analysis of the Lysine Acetylome in <i>Vibrio parahemolyticus</i> by Jianyi Pan (1520743)

“…Overall, we identified 1413 lysine acetylation sites in 656 proteins, which account for 13.6% of the total proteins in the cells; this is the highest ratio of acetyl proteins that has so far been identified in bacteria. The bioinformatics analysis of the acetylome showed that the acetylated proteins are involved in a wide range of cellular functions and exhibit diverse subcellular localizations. …”

A Supervised Molecular Dynamics Approach to Unbiased Ligand–Protein Unbinding by Giuseppe Deganutti (2609257)

“…However, a known limitation of MD is that the time scales are usually far from those involved in ligand–receptor unbinding events. …”

Direct Observation of Calcium-Independent Intercellular ATP Signaling in Astrocytes by Ziqiang Wang (1628740)

“…Adenosine triphosphate (ATP) is assumed to be involved in the regulation of many extracellular signaling systems including calcium wave propagation. …”

Video5_Dopamine Modulation of Drosophila Ellipsoid Body Neurons, a Nod to the Mammalian Basal Ganglia.MP4 by Giovanni Frighetto (5927597)

“…However, the neural mechanisms and the neurotransmitters involved in these processes remain unclear. Here, we exploited an in vivo bioluminescence Ca²⁺ imaging technique to record the activity in targeted neurons of the ellipsoid body (EB). …”

Systematic Analysis of the Lysine Acetylome in <i>Vibrio parahemolyticus</i> by Jianyi Pan (1520743)

“…Overall, we identified 1413 lysine acetylation sites in 656 proteins, which account for 13.6% of the total proteins in the cells; this is the highest ratio of acetyl proteins that has so far been identified in bacteria. The bioinformatics analysis of the acetylome showed that the acetylated proteins are involved in a wide range of cellular functions and exhibit diverse subcellular localizations. …”

A small ribosome-associated ncRNA globally inhibits translation by restricting ribosome dynamics by Julia Reuther (3364277)

“…Cumulatively, these discoveries reveal the mode of action of a rancRNA involved in modulating protein biosynthesis at a thus far unequalled precision.…”

A Supervised Molecular Dynamics Approach to Unbiased Ligand–Protein Unbinding by Giuseppe Deganutti (2609257)

“…However, a known limitation of MD is that the time scales are usually far from those involved in ligand–receptor unbinding events. …”

Systematic Analysis of the Lysine Acetylome in <i>Vibrio parahemolyticus</i> by Jianyi Pan (1520743)

“…Overall, we identified 1413 lysine acetylation sites in 656 proteins, which account for 13.6% of the total proteins in the cells; this is the highest ratio of acetyl proteins that has so far been identified in bacteria. The bioinformatics analysis of the acetylome showed that the acetylated proteins are involved in a wide range of cellular functions and exhibit diverse subcellular localizations. …”

Video1_Dopamine Modulation of Drosophila Ellipsoid Body Neurons, a Nod to the Mammalian Basal Ganglia.MP4 by Giovanni Frighetto (5927597)

“…However, the neural mechanisms and the neurotransmitters involved in these processes remain unclear. Here, we exploited an in vivo bioluminescence Ca²⁺ imaging technique to record the activity in targeted neurons of the ellipsoid body (EB). …”

Skin Cornification Proteins Provide Global Link between ROS Detoxification and Cell Migration during Wound Healing by Wilbert P. Vermeij (244583)

“…Apparently, SPRR proteins have a far more widespread role in wound healing and tissue remodelling than their established function in skin cornification. …”

Multidrug-Resistance Related Long Non-Coding RNA Expression Profile Analysis of Gastric Cancer by Ying Wang (11406)

“…However, the mechanisms underlying MDR of GC remains far from fully understood. The aim of this study is to illustrate the potential mechanisms of the MDR of GC at mainly the long non-coding RNA (lncRNA) level. …”

Table S1. Compounds mixtures (ten-in-one) information. from Small molecule activates citrullination through targeting PAD2 by Xue Zhang (166886)

“…Citrullination is a post-translational modification catalysed by peptidyl arginine deiminase (PAD) enzymes, dysregulation of protein citrullination is involved in various pathological disorders. During the last decade, a panel of citrullination inhibitors have been developed, while small molecules activating citrullination are rarely reported so far. …”

DataSheet_1_Understanding Sources of Variation to Improve the Reproducibility of Radiomics.pdf by Binsheng Zhao (3608099)

“…The fast dispersal of this new methodology has benefited from the existing advances of the core technologies involved in radiomics workflow: image acquisition, tumor segmentation, feature extraction and machine learning. …”

Data_Sheet_1_miR-146a Plasma Levels Are Not Altered in Alzheimer’s Disease but Correlate With Age and Illness Severity.PDF by Elisabetta Maffioletti (8317572)

“…<p>miR-146a is a microRNA (miRNA) involved in neuroinflammation and aging; alterations in its expression were described in Alzheimer’s disease (AD). …”

Image_1_Barley Root Proteome and Metabolome in Response to Cytokinin and Abiotic Stimuli.TIF by Miroslav Berka (9570662)

“…<p>Cytokinin is a phytohormone involved in the regulation of diverse developmental and physiological processes in plants. …”

Table_1_Global Status of Phytoplasma Diseases in Vegetable Crops.DOCX by Shweta Kumari (6885479)

“…It is moreover essential to understand the molecular basis of phytoplasma-vector interaction, epidemiology and other factors involved in disease development in order to reduce the disease outbreaks. …”

Video6_Dopamine Modulation of Drosophila Ellipsoid Body Neurons, a Nod to the Mammalian Basal Ganglia.MP4 by Giovanni Frighetto (5927597)

“…However, the neural mechanisms and the neurotransmitters involved in these processes remain unclear. Here, we exploited an in vivo bioluminescence Ca²⁺ imaging technique to record the activity in targeted neurons of the ellipsoid body (EB). …”

Frequency Band-Specific Electrical Brain Stimulation Modulates Cognitive Control Processes by Joram van Driel (649847)

“…<div><p>A large body of findings has tied midfrontal theta-band (4–8 Hz) oscillatory activity to adaptive control mechanisms during response conflict. Thus far, this evidence has been correlational. To evaluate whether theta oscillations are causally involved in conflict processing, we applied transcranial alternating current stimulation (tACS) in the theta band to a midfrontal scalp region, while human subjects performed a spatial response conflict task. …”