Integrating Computational Biology and Forward Genetics in <em>Drosophila</em> Dahkki Stein Aerts (9837)

“…In this work, we demonstrate that integrating genome-wide computational gene prioritization with large-scale genetic screening is a powerful tool for functional gene discovery. To discover genes involved in neural development in <em>Drosophila</em>, we extend our strategy for the prioritization of human candidate disease genes to functional prioritization in <em>Drosophila</em>. …”

Data_Sheet_6_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_3_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx Dahkki Hai Fang (160549)

“…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …”

Table_5_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.DOCX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_4_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.DOCX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Image_3_Integrated transcriptomic and pathway analyses of sorghum plants revealed the molecular mechanisms of host defense against aphids.jpg Dahkki Kumar Shrestha (18773950)

“…<p>Sugarcane aphid has emerged as a major pest of sorghum recently, and a few sorghum accessions were identified for resistance to this aphid so far. However, the molecular and genetic mechanisms underlying this resistance are still unclear. …”

Gating Motions in Voltage-Gated Potassium Channels Revealed by Coarse-Grained Molecular Dynamics Simulations Dahkki Werner Treptow (830057)

“…Voltage-gated potassium (Kv) channels are ubiquitous transmembrane proteins involved in electric signaling of excitable tissues. …”

Table_1_Structure and Dynamics in the ATG8 Family From Experimental to Computational Techniques.DOCX Dahkki Valentina Sora (8955257)

“…We here summarize the main results collected so far and discuss the future perspectives within the field and the knowledge gaps. …”

Walking the Line: A Fibronectin Fiber-Guided Assay to Probe Early Steps of (Lymph)angiogenesis Dahkki Maria Mitsi (839146)

“…While it is described that extracellular matrix (ECM) fibers are involved in the spatiotemporal regulation of angiogenesis, current angiogenesis assays are not specifically designed to dissect and quantify the underlying molecular mechanisms of how the fibrillar nature of ECM regulates vessel sprouting. …”

Video_2_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4 Dahkki Milvia Alata (8925635)

“…These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood.…”

Design and Pharmacological Characterization of α₄β₁ Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Anta... Dahkki Michele Anselmi (14852037)

“…α₄β₁ integrin is a cell adhesion receptor deeply involved in the migration and accumulation of leukocytes. …”

Image_4_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.JPEG Dahkki Keisha D. Carlson (298516)

“…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …”

Image_1_Primary Hepatoid Adenocarcinoma of Gallbladder With MB21D2/GALNT12/ARID2 Mutations: A Case Report.tif Dahkki Zhenyu Li (295387)

“…The genetic changes involved in this type of adenocarcinoma were unexplained so far. …”

Data_Sheet_1_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.PDF Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_2_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_3_Integrated transcriptomic and pathway analyses of sorghum plants revealed the molecular mechanisms of host defense against aphids.xlsx Dahkki Kumar Shrestha (18773950)

“…<p>Sugarcane aphid has emerged as a major pest of sorghum recently, and a few sorghum accessions were identified for resistance to this aphid so far. However, the molecular and genetic mechanisms underlying this resistance are still unclear. …”

Data_Sheet_11_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Image_1_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.JPEG Dahkki Keisha D. Carlson (298516)

“…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …”

Table_15_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_10_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”