Genotyping and Phylogenetic Analysis of <em>Yersinia pestis</em> by MLVA: Insights into the Worldwide Expansion of Central Asia Plague Foci per Yanjun Li (46396)

“…Most investigations so far have focused on the typical <em>pestis</em> subspecies representatives found outside of China, whereas the understanding of the emergence of this human pathogen requires the investigation of strains belonging to subspecies <em>pestis</em> from China and to the Microtus biovar.…”

Image_1_Allocation of Interferon Gamma mRNA Positive Cells in Caecum Hallmarks a Protective Trait Against Histomonosis.JPEG per Fana Alem Kidane (5296946)

“…The protective mechanisms that underpin the vaccine-induced immune response are not resolved so far. Therefore, the actual study aimed to evaluate the location and quantitative distribution patterns of signature cytokines of type 1 [interferon gamma (IFN-γ)] or type 2 [interleukin (IL)-13] immune responses in vaccinated or infected hosts. …”

Unveiling Current Guanaco Distribution in Chile Based upon Niche Structure of Phylogeographic Lineages: Andean Puna to Subpolar Forests per Benito A. González (393011)

“…Here we model the environmental niche structure and distribution of the recently resolved phylogeography of guanaco (<i>Lama guanicoe</i>) lineages on the western slope of the southern Andes. …”

Elucidation of the Catalytic Apparatus and Mechanism of Human Chitotriosidase‑1 per Dorota Niedzialek (1974655)

“…Finally, we demonstrated that binding of the first-in-class inhibitor OATD-01 induces subtle yet far-reaching dynamical changes within the active site, leading to dissociation of the immunoglobulin-like heterodimer and disruption of interactions with biological partners implicated in disease pathogenesis. …”

Image_2_Allocation of Interferon Gamma mRNA Positive Cells in Caecum Hallmarks a Protective Trait Against Histomonosis.JPEG per Fana Alem Kidane (5296946)

“…The protective mechanisms that underpin the vaccine-induced immune response are not resolved so far. Therefore, the actual study aimed to evaluate the location and quantitative distribution patterns of signature cytokines of type 1 [interferon gamma (IFN-γ)] or type 2 [interleukin (IL)-13] immune responses in vaccinated or infected hosts. …”

Elucidation of the Catalytic Apparatus and Mechanism of Human Chitotriosidase‑1 per Dorota Niedzialek (1974655)

“…Finally, we demonstrated that binding of the first-in-class inhibitor OATD-01 induces subtle yet far-reaching dynamical changes within the active site, leading to dissociation of the immunoglobulin-like heterodimer and disruption of interactions with biological partners implicated in disease pathogenesis. …”

Data_Sheet_1_Co-infection of two eukaryotic pathogens within clam populations in Arcachon Bay.DOCX per Sarah Itoïz (8446872)

“…This ecological study demonstrates that the detection and quantification of both parasitic species, P. olseni and P. chesapeaki, is essential and timely in resolving cryptic infections and their consequences on individual hosts and clam populations.…”

Data from: Quantifying seed rain patterns in a remnant and a chronosequence of restored tallgrass prairies in north central Missouri per Katherine Wynne (22078346)

“…However, knowledge of seed rain patterns is limited to those observed in forests and late-assembling grasslands, which might not reflect early-assembling communities such as newly restored grasslands. Resolving this gap in our understanding provides further insight into the role of seed dispersal.…”

Data_Sheet_1_Prenatal Genetic Counseling in a Chinese Pregnant Woman With Rare Thalassemia: A Case Report.PDF per Liangying Zhong (5642819)

“…An intronic variant located far from obvious regulatory sequences in the HBB gene could be very difficult to evaluate as it may affect the mRNA processing or cause β-thalassemia (β-thal). …”

<i>D</i>₂-Symmetric Dimer of 1,1‘-Binaphthyl and Its Chiral π-Conjugated Carbodianion per Andrzej Rajca (1339899)

“…However, CD and UV spectra, and cyclic voltammetric data of (<i>R</i>)(+)-<b>3 </b>are consistent with small, but far from negligible, conjugation (or homoconjugation) between the naphthalene moieties. …”

Elucidation of the Catalytic Apparatus and Mechanism of Human Chitotriosidase‑1 per Dorota Niedzialek (1974655)

“…Finally, we demonstrated that binding of the first-in-class inhibitor OATD-01 induces subtle yet far-reaching dynamical changes within the active site, leading to dissociation of the immunoglobulin-like heterodimer and disruption of interactions with biological partners implicated in disease pathogenesis. …”

Data_Sheet_2_Co-infection of two eukaryotic pathogens within clam populations in Arcachon Bay.DOCX per Sarah Itoïz (8446872)

“…This ecological study demonstrates that the detection and quantification of both parasitic species, P. olseni and P. chesapeaki, is essential and timely in resolving cryptic infections and their consequences on individual hosts and clam populations.…”

<i>Superstesaster promissor</i> gen. et sp. nov., a new starfish (Echinodermata, Asteroidea) from the Early Triassic of Utah, USA, filling a major gap in the phylogeny of asteroids per Loïc Villier (3933644)

“…Including 30 species and 70 morphological characters, it is the most comprehensive phylogeny produced for fossil starfishes so far. Relationships among Palaeozoic forms remain poorly resolved, but their position in the tree is grossly consistent with stratigraphy. …”

Plk2 interacts with NPM/B23 <i>in vivo</i> and <i>in vitro</i>. per Annekatrin Krause (365995)

“…IgG, random antibody control. <b>D</b> Far Western blot analysis. Recombinant His-tagged NPM/B23 was resolved by SDS-PAGE, blotted onto nitrocellulose and incubated with GST-Plk2 PBD, -PBD mutant or GST (control) to allow interaction. …”

Large Ground-State and Excited-State Crystal Field Splitting of 8-fold-Coordinate Cm³⁺ in [Y(H₂O)₈]Cl₃·15-crown-5 per Patric Lindqvist-Reis (2132083)

“…The transitions between the ground state and the respective lowest crystal-field levels of the excited states exhibit narrow fluorescence lines, resolving the four crystal-field levels of the ground state as sharp, well-resolved lines at about 0, 10, 19, and 35 cm^-1. …”

How I joined the Intelligence Corps per Their Finest Hour Project Team (18604667)

“…</p><p>I was made a Guard Runner, which involved me standing at the main entrance gate with a large stick held behind my back and when a visitor came to the gate I would be assigned to take the visitor to the required destination and another Guard Runner would take my place. …”

Facilitating the Recruitment of Minority Ethnic People into Research: Qualitative Case Study of South Asians and Asthma per Aziz Sheikh (18504)

“…A recent systematic review and meta-analysis found that UK South Asians are at three times increased risk of hospitalisation for asthma when compared to white Europeans. US asthma trials are far more likely to report enrolling minority ethnic people into studies than those conducted in Europe. …”

Data_Sheet_1_The Effect of Magnesium on Reperfusion Arrhythmias in STEMI Patients, Treated With PPCI. A Systematic Review With a Meta-Analysis and Trial Sequential Analysis.PDF per Laszlo B. Szapary (9966656)

“…A statistical analysis was performed on three randomized-controlled trials using three common parameters, involving 336 patients Trial sequential analysis (TSA) was applied to assess the risk of random error associated with sparse data and multiple testing which can affect cumulative meta-analysis. …”

Table_1_The Synaptic Gene Study: Design and Methodology to Identify Neurocognitive Markers in Phelan-McDermid Syndrome and NRXN1 Deletions.DOCX per Jennifer Cooke (2523625)

“…<p>Synaptic gene conditions, i.e., “synaptopathies,” involve disruption to genes expressed at the synapse and account for between 0.5 and 2% of autism cases. …”

Altered Activation in Cerebellum Contralateral to Unilateral Thalamotomy May Mediate Tremor Suppression in Parkinson’s Disease: A Short-Term Regional Homogeneity fMRI Study per Zhi Wen (458994)

“…The neural basis underlying thalamotomy is complex; cerebellum involvement is far beyond cerebello-thalamic tract breakage.…”