Proteome Analysis of <i>Myxococcus </i><i>x</i><i>anthus</i> by Off-Line Two-Dimensional Chromatographic Separation Using Monolithic Poly-(styrene-divinylbenzene) Columns Combined... Dahkki Christian Schley (2525236)

“…High-molecular polyketide synthetases and nonribosomal peptide synthetases, known to be involved in the biosynthesis of various secondary metabolites, were readily detected. …”

Table_8_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Data_Sheet_10_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Data_Sheet_2_Complete Genome Assemblies of All Xanthomonas translucens Pathotype Strains Reveal Three Genetically Distinct Clades.FASTA Dahkki Florian Goettelmann (12177245)

“…Further investigation of these genes could help to identify genes that are critically involved in pathogenicity and/or host adaptation, setting the grounds for the development of new resistant cultivars.…”

Data_Sheet_2_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.xlsx Dahkki Keisha D. Carlson (298516)

“…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …”

Revealing a Two-Loop Transcriptional Feedback Mechanism in the Cyanobacterial Circadian Clock Dahkki Stefanie Hertel (389546)

“…<div><p>Molecular genetic studies in the circadian model organism <i>Synechococcus</i> have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription. …”

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α) Dahkki Armin Thalhammer (233088)

“…Some of these processes are centrally involved in regulation of cellular responses to hypoxia. …”

Video_6_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4 Dahkki Milvia Alata (8925635)

“…These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood.…”

DataSheet1_A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities.docx Dahkki Frida Mandik (14255618)

“…The condition is caused by a homozygous or compound heterozygous mutation in fatty acid 2 hydroxylase (FA2H), whose encoded protein synthesizes 2-hydroxysphingolipids and 2-hydroxyglycosphingolipids and is therefore involved in sphingolipid metabolism. A few FAHN model organisms have already been established and give the first insight into symptomatic effects. …”

Data_Sheet_13_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.PDF Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Video_1_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4 Dahkki Milvia Alata (8925635)

“…These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood.…”

Data_Sheet_8_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_2_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx Dahkki Hai Fang (160549)

“…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …”

Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity Dahkki Vibha Singh (3937961)

“…<p>The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far. …”

Image_6_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.JPEG Dahkki Keisha D. Carlson (298516)

“…Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth. …”

Table_1_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Table_6_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx Dahkki Hai Fang (160549)

“…</p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes. …”

Table_12_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX Dahkki Ângela Brito (9090569)

“…This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains. …”

Receptor Tyrosine Kinase (RTK) Mediated Tyrosine Phosphor-Proteome from Drosophila S2 (ErbB1) Cells Reveals Novel Signaling Networks Dahkki Srinivasan Krishnamoorthy (52404)

“…Tyrosine phosphorylation events mediated by aberrant activation of Receptor Tyrosine Kinase (RTK) pathways have been proven to be involved in the development of several diseases including cancer. …”

Design and Pharmacological Characterization of α₄β₁ Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Anta... Dahkki Michele Anselmi (14852037)

“…α₄β₁ integrin is a cell adhesion receptor deeply involved in the migration and accumulation of leukocytes. …”