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Plate-bound co-stimulatory 1C6 antibody negatively impacts T cell activation.
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Bead-bound antibody utilizing 5B8 co-stimulation demonstrates superior T cell activation.
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5B8 co-stimulation demonstrates superior T cell activation for plate-bound antibody.
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Optimal concentrations of ConA and PMA/I are limited by impact on viability.
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Flow cytometry was utilized to verify successful antibody-bead conjugation.
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Nickel-Hydride-Catalyzed Hydroalkylation of Cyclic Phosphinates: Generation of Enantioenriched Phosphorus and Carbon Stereocenters
Published 2025“…In contrast to numerous examples leveraging Ni–H catalysis for the construction of a single or two adjacent stereocenters, accessing two stereoenriched 1,3-chiral centers has so far remained underexplored. Furthermore, Ni–H chemistry is yet to be extended beyond the construction of chirality at carbon. …”
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