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4361
An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits
Published 2010“…However, the genetic variants identified so far only explain a small proportion of the heritability for complex traits. …”
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4362
Data_Sheet_1_The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in...
Published 2018“…Although adenosine exerts clear neuroprotective effects through A<sub>1</sub> receptors during ischemia, the use of selective A<sub>1</sub> receptor agonists is hampered by their undesirable peripheral side effects. So far, no evidence is available on the involvement of adenosine A<sub>2B</sub> receptors in cerebral ischemia. …”
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4363
Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide−Alkyne Cycloaddition
Published 2010“…We described in a previous communication a variant of the popular Cu<sup>I</sup>-catalyzed azide−alkyne cycloaddition (AAC) process where 5 mol % of Cu(OAc)<sub>2</sub> in the absence of any added reducing agent is sufficient to enable the reaction. 2-Picolylazide (<b>1</b>) and 2-azidomethylquinoline (<b>2</b>) were found to be by far the most reactive carbon azide substrates that convert to 1,2,3-triazoles in as short as a few minutes under the discovered conditions. …”
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4364
31959: A University Online
Published 2023“…Working in IT but also English I saw the extraordinary efforts that went on during this period from everyone as we moved the entire University to online teaching in the space of a few weeks. This involved boosting IT Infrastructure, sorting our training, but then moving to thinking about proper online teaching and examining where the burden fell to the divisions, departments, libraries, colleagues in the Centre for Teaching and Learning, and many others. …”
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4365
pH modulates the role of SP6 RNA polymerase in transcription process: an <i>in silico</i> study
Published 2023“…This model is essential as no structure was solved for this enzyme using any of the standard structural biology techniques.…”
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4366
E02481: The Martyrdom of *Alexander, Eventius and Theodolus (respectively bishop, priest and deacon, all martyrs of Rome, buried on the via Nomentana, S00127), and of *Hermes (mart...
Published 2017“…Theodolus is also interrogated and shows similar resolve.<br><br>§ 19: Aurelianus orders a furnace to be h…”
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4367
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…The Greedy, LP and ILP algorithms consistently achieve the optimal coverage with far fewer donors than the random choice. In all cases, the number of randomly-selected donors required to achieve a desired coverage increases with increasing population. …”
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4368
Chain Structures in Alkali Metal Borophosphates: Synthesis and Characterization of K<sub>3</sub>[BP<sub>3</sub>O<sub>9</sub>(OH)<sub>3</sub>] and Rb<sub>3</sub>[B<sub>2</sub>P<sub...
Published 2005“…While for the rubidium compound a loop-branched chain motif is found as common for most of the chain anions in alkali metal borophosphates, the crystal structure of the potassium phase comprises the first open-branched chain with the highest phosphate content found so far in this group of compounds. Both chain anions are closely related to known anhydrous or hydrated phases, and the structural relations are discussed in terms of how the presence of OH groups and hydrogen bonds as well as number, charge, and size of charge balancing cations influence the 3D structural arrangement. …”
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4369
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…The Greedy, LP and ILP algorithms consistently achieve the optimal coverage with far fewer donors than the random choice. In all cases, the number of randomly-selected donors required to achieve a desired coverage increases with increasing population. …”
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4370
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…The Greedy, LP and ILP algorithms consistently achieve the optimal coverage with far fewer donors than the random choice. In all cases, the number of randomly-selected donors required to achieve a desired coverage increases with increasing population. …”
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4371
Brp accumulates in <i>srpk79D</i> mutant nerves.
Published 2009“…Images in (B, E, and H) and (C, F, and I) were taken at an exposure in which small, infrequent anti-Brp puncta could be resolved in wild-type nerves. This resulted in overexposure of the Brp puncta in srpk79D mutant nerves. …”
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4372
Wol GreA through its C-terminal domain interacts with α2ββ′σ subunits of RNAP holoenzyme.
Published 2014“…Lane M, standard protein marker; Lane 1-3, 10-U of RNAP holoenzyme (α2ββ′σ subunits) were resolved followed by Ponceau staining. (D) Far Western Blotting was performed to determine the specific interaction of Wol GreA and CTD with α2ββ′σ subunits of RNAP. …”
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4373
Early Lanthanide(III) Ate Complexes Featuring Ln–Si Bonds (Ln = La, Ce): Synthesis, Structural Characterization, and Bonding Analysis
Published 2022“…<sup>29</sup>Si solid-state NMR measurements on the diamagnetic silyl lanthanum complexes were conducted, and large one-bond hyperfine splitting constants arising from = 7/2) were resolved. Computational studies on these silyl lanthanum and cerium complexes suggested the polarized covalent feature of the Ln–Si bonds, which is in line with the measured large <sup>1</sup><i>J</i><sub><sup>139</sup>La–Si</sub> splitting constants.…”
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4374
Cationic Rhodium Complexes with Hemilabile Phosphine Ligands as Polymerization Catalyst for High Molecular Weight Stereoregular Poly(phenylacetylene)
Published 2009“…The mechanism of PA polymerization has been investigated by spectroscopic means, under stoichiometric and catalytic conditions, and shows an active role of the hemilabile phosphine ligand both in the initiation and, probably, in the termination steps through proton transfer processes involving the hemilabile fragment of the ligand.…”
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4375
Non-<i>IG</i> Aberrations of <i>FOXP1</i> in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1
Published 2014“…<div><p>The transcription factor FOXP1 is implicated in the pathogenesis of B-cell lymphomas through chromosomal translocations involving either immunoglobulin heavy chain (<i>IGH</i>) locus or non-<i>IG</i> sequences. …”
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4376
Table_1_The double-sided of human leukocyte antigen-G molecules in type 1 autoimmune hepatitis.docx
Published 2022“…<p>The immunomodulatory effects of HLA-G expression and its role in cancers, human liver infections and liver transplantation are well documented, but so far, there are only a few reports addressing autoimmune liver diseases, particularly autoimmune hepatitis (AIH).…”
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4377
E00639: Gregory of Tours, in his Glory of the Martyrs (89), recounts three miracles effected in western and north-western Gaul by relics of *Vincent (deacon and martyr of Saragossa...
Published 2015“…Gregory of Tours, Glory of the Martyrs 89<br><br>Gregory relates three separate miracle stories involving relics of Vincent:<br><br>Vincent, deacon and martyr, was martyred in Spain. …”
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4378
E02836: The Greek Martyrdom of *Polyeuktos (soldier and martyr of Melitene, S00325), of the 4th/5th c., recounts the story of two soldiers and friends, the Christian Nearchos and t...
Published 2017“…His wife, Paulina, appears and asks him how he has been involved in all this. Defiantly, he suggests that she converts too. …”
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4379
Developing culture-appropriate student assessments
Published 2023“…</p><p>“While no formal evaluation of the SMSA has been conducted so far, the general feeling of students and faculty is that it provides a platform for hands-on application and evaluation of skills,” says Kheir. …”
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4380
January 1939 to April 1945 BEF to Captivity and back to Blighty
Published 2024“…<br>Whilst he was at these camps, he was tasked with labouring duties with the working parties. to the following remote, areas/townships<br>Poppolau Upper Selisia (Forestry and mining) The work involved felling trees cutting into logs stripping the bark ready for paper making and props for use in the mines.…”