DataSheet_1_Harnessing monocrop breeding strategies for intercrops.zip por Reena Dubey (17778594)

“...We show that the optimal stage for switching from monocrop to intercrop testing should be adapted to the specificity of the crop and the heritability of the traits involved. However, the genetic correlation between the monocrop and intercrop trait performance is the primary driver of the intercrop breeding scheme optimization process....”

Efficient Construction of Homozygous Diploid Strains Identifies Genes Required for the Hyper-Filamentous Phenotype in <em>Saccharomyces cerevisiae</em> por Kentaro Furukawa (199753)

“...Those include well-known positive regulator genes for filamentous growth signaling pathways, genes involved in mitochondrial function, DNA damage checkpoint, chromatin remodeling, and cell cycle, and also previously uncharacterized genes. ...”

The Effects of Extra-Somatic Weapons on the Evolution of Human Cooperation towards Non-Kin por Tim Phillips (559406)

“...Widespread weapons use could have made disputes within hominin groups far more lethal and also equalized power between individuals. ...”

Table 3_Assessment of the effects of cannabidiol and a CBD-rich hemp extract in Caenorhabditis elegans.docx por Jessica A. Camacho (19769295)

“...Multiple pathways and signaling cascades involved in organismal development and neuronal function, including endocannabinoid synthesis and signaling systems, are well conserved across phyla, suggesting that Caenorhabditis elegans can model the in vivo effects of exogenous cannabinoids. ...”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia por Nagore I. Marín-Ramos (1600555)

“...In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. ...”

Table4_Functional analysis of differently expressed ferroptosis-related genes in patients with mitral valve prolapse.XLSX por Hui Xie (195238)

“...Notably, these genes are primarily involved in the extracellular region and p53 signaling pathway....”

Image_1_Neutrophils Encompass a Regulatory Subset Suppressing T Cells in Apparently Healthy Cattle and Mice.tif por Marion Rambault (10199990)

“...For a long time, these first line defenders were considered as microbe killers. However their role is far more complex as cross talk with T cells or dendritic cells have been described for human or mouse neutrophils. ...”

Table_2_Integrated Microbiome and Metabolome Analysis Reveals a Positive Change in the Intestinal Environment of Myostatin Edited Large White Pigs.pdf por Yangli Pei (727447)

“...While both genotype and microbial composition are known to affect the host phenotype, so far there has been no systematic study to detect the changes in the intestinal microbial composition and metabolome of MSTN single copy mutant pigs. ...”

Table_1_Comparative Genomics of Potato Common Scab-Causing Streptomyces spp. Displaying Varying Virulence.DOCX por Cindy Hudec (5527016)

“...Their phylogenomic affiliation was determined, their pan-genome was characterized, and pathogenic determinants involved in their virulence, ranging from weak to aggressive, were compared. 13 out of 14 strains clustered with Streptomyces scabiei, while the last strain clustered with Streptomyces acidiscabies. ...”

Image_6_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif por Yunpeng Cao (3609377)

“...Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis....”

Image_1_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif por Yunpeng Cao (3609377)

“...Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis....”

Functional autoantibodies in patients with different forms of dementia por Gerd Wallukat (252625)

“...<div><p>Dementia in general and Alzheimer’s disease in particular is increasingly seen in association with autoimmunity being causatively or supportively involved in the pathogenesis. Besides classic autoantibodies (AABs) present in dementia patients, there is the new autoantibody class called functional autoantibodies, which is directed against G-protein coupled receptors (GPCRs; GPCR-AABs) and are seen as pathogenic players. ...”

The Effect of Temperature on the Proteome of Recombinant <i>Pichia pastoris</i> por Martin Dragosits (2388358)

“...The impact of environmental factors on the productivity of yeast cells is poorly investigated so far. Therefore, it is a major concern to improve the understanding of cellular physiology of microbial protein production hosts, including the methylotrophic yeast <i>Pichia pastoris....”

Video_1_Reconstruction of Intratelencephalic Neurons in the Mouse Secondary Motor Cortex Reveals the Diverse Projection Patterns of Single Neurons.MPG por Hui-Min Lin (3455366)

“...We obtained a neuron with an axonal length of 318.43 mm, which is by far the longest reported axonal length. Our results show that all individual neurons in the MOs, regardless of whether they are located in layer 2/3 or layer 5, display diverse projection patterns and projection strengths, implying that these neurons might be involved in different brain circuits at different intensities. ...”

Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis por Sonal (631310)

“...We have used genetic analysis in combination with cellular imaging to show that zebrafish <i>goosepimples/myosin Vb</i> regulates plasma membrane homeostasis and is involved in maintenance of cell size in the periderm, the outermost epidermal layer. ...”

Hydrogen Tunneling above Room Temperature Evidenced by Infrared Ion Spectroscopy por Mathias Schäfer (1694968)

“...While hydrogen tunneling at elevated temperatures has, for instance, often been postulated in biochemical processes, spectroscopic proof is thus far limited to cryogenic conditions, under which thermal reactivity is negligible. ...”

Video_2_BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo.WMV por Wibke Singer (306957)

“...<p>Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. ...”

Image_1_A Novel Device of Reaching, Grasping, and Retrieving Task for Head-Fixed Mice.PDF por Satoshi Manita (12532441)

“...To understand the mechanism for controlling this movement at the neural circuit level, it is necessary to observe the activity of individual neurons involved in the movement. For stable electrophysiological or optical recordings of neural activity in a behaving animal, head fixation effectively minimizes motion artifacts. ...”

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia por Nagore I. Marín-Ramos (1600555)

“...In this work we report a potent ICMT inhibitor, compound <b>3</b> [UCM-1336, IC₅₀ = 2 μM], which is selective against the other enzymes involved in the post-translational modifications of Ras. ...”

Image_1_A Chinese White Pear (Pyrus bretschneideri) BZR Gene PbBZR1 Act as a Transcriptional Repressor of Lignin Biosynthetic Genes in Fruits.tif por Yunpeng Cao (3609377)

“...Our study traces the evolution of BZR gene family members in Rosaceae genomes and illustrates that the rates of gene loss and gain are far from equilibrium in different species. At the same time, our results suggest that PbBZR1 may be involved in the negative regulation of lignin biosynthesis....”