Image_3_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG von Franziska Handel (9440429)

“… <p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6).  …”

Characterization of <em>Leishmania donovani</em> MCM4: Expression Patterns and Interaction with PCNA von Neha Minocha (211709)

“… <div><p>Events leading to origin firing and fork elongation in eukaryotes involve several proteins which are mostly conserved across the various eukaryotic species.  …”

Image_2_Investigation of the Autoregulator-Receptor System in the Pristinamycin Producer Streptomyces pristinaespiralis.JPEG von Franziska Handel (9440429)

“… <p>Pristinamycin biosynthesis in Streptomyces pristinaespiralis is governed by a complex hierarchical signaling cascade involving seven different transcriptional regulators (SpbR, PapR1, PapR2, PapR3, PapR4, PapR5, and PapR6).  …”

A new paramutation-like example at the <i>Delta</i> gene of <i>Drosophila</i> von Maria Capovilla (220512)

“… Distinct from paramutation events so far described in <i>Drosophila</i>, here we deal with a dominant effect on a single gene involving variable hereditary signals. …”

Molecular Epidemiology of <i>Brucella abortus</i> in Northern Ireland—1991 to 2012 von Adrian Allen (624953)

“… Bovine brucellosis caused by <i>Brucella abortus</i> has far reaching animal health and economic impacts at both the local and national levels.  …”

A grid-aware emergency response model for natural disasters. Appendices 2 - 5. von Eleana Asimakopoulou (7182590)

“… The approach adopted in the research involved literature reviews, case studies, face-toface structured interviews with emergency management stakeholders and leT experts, model development using Soft Systems Methodology (SSM) linked to Information Systems Development Methodologies (lSDMs), and finally, one-to-one evaluation exercises. ease studies and interviews involving two member states of the European Union were carried out to investigate current practices and to highlight the limitations that emergency management stakeholders face during response operations.  …”

Proteome Analysis of <i>Myxococcus </i><i>x</i><i>anthus</i> by Off-Line Two-Dimensional Chromatographic Separation Using Monolithic Poly-(styrene-divinylbenzene) Columns Combined... von Christian Schley (2525236)

“… High-molecular polyketide synthetases and nonribosomal peptide synthetases, known to be involved in the biosynthesis of various secondary metabolites, were readily detected.  …”

Table_8_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.XLSX von Ângela Brito (9090569)

“… This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains.  …”

Data_Sheet_10_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA von Ângela Brito (9090569)

“… This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains.  …”

Data_Sheet_2_Complete Genome Assemblies of All Xanthomonas translucens Pathotype Strains Reveal Three Genetically Distinct Clades.FASTA von Florian Goettelmann (12177245)

“… Further investigation of these genes could help to identify genes that are critically involved in pathogenicity and/or host adaptation, setting the grounds for the development of new resistant cultivars. …”

Data_Sheet_2_Phytochrome A Regulates Carbon Flux in Dark Grown Tomato Seedlings.xlsx von Keisha D. Carlson (298516)

“… Most phytochromes are activated by red light and de-activated by far-red light, but phytochrome A (phyA) is responsive to both and plays an important role during the well-studied transition of seedlings from dark to light growth.  …”

Revealing a Two-Loop Transcriptional Feedback Mechanism in the Cyanobacterial Circadian Clock von Stefanie Hertel (389546)

“… <div><p>Molecular genetic studies in the circadian model organism <i>Synechococcus</i> have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription.  …”

Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α) von Armin Thalhammer (233088)

“… Some of these processes are centrally involved in regulation of cellular responses to hypoxia.  …”

Video_6_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4 von Milvia Alata (8925635)

“… These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood. …”

DataSheet1_A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities.docx von Frida Mandik (14255618)

“… The condition is caused by a homozygous or compound heterozygous mutation in fatty acid 2 hydroxylase (FA2H), whose encoded protein synthesizes 2-hydroxysphingolipids and 2-hydroxyglycosphingolipids and is therefore involved in sphingolipid metabolism. A few FAHN model organisms have already been established and give the first insight into symptomatic effects.  …”

Data_Sheet_13_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.PDF von Ângela Brito (9090569)

“… This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains.  …”

Video_1_Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the taiep Model.MP4 von Milvia Alata (8925635)

“… These white matter changes are progressive and can be involved in the clinical deterioration. Hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) gives rise to a spectrum of clinical signs whose pathophysiology still needs to be understood. …”

Data_Sheet_8_Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine Cyanobacterium Hyella patelloides.FASTA von Ângela Brito (9090569)

“… This genome is the largest of the thirteen baeocyte-forming cyanobacterial genomes sequenced so far, and diverges from the most closely related strains.  …”

Table_2_Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease.xlsx von Hai Fang (160549)

“… </p>Results<p>We generated an atlas of genetic target prioritization, with the top targets highly enriched for genes involved in the NF-kB regulation, including interaction neighbors of inflammasome genes.  …”

Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity von Vibha Singh (3937961)

“… <p>The Tousled Like kinases (TLKs) are involved in numerous cellular functions, including the DNA Damage Response (DDR), but only a handful of substrates have been identified thus far.  …”