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28081
Table_1_Functional Dystonia: Differentiation From Primary Dystonia and Multidisciplinary Treatments.docx
Publicat 2021“…<p>Dystonia is a common movement disorder, involving sustained muscle contractions, often resulting in twisting and repetitive movements and abnormal postures. …”
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28082
FusionHub: A unified web platform for annotation and visualization of gene fusion events in human cancer - Fig 4
Publicat 2018“…Domain view shows three different ways by which CCDC6—RET fusion gene is formed (B). Network view shows the fusion gene network involving CCDC6 gene and its fusion interaction partners.…”
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28083
<i>Ex vivo</i> voxel based morphometry identified areas of significant enlargement in trained animals relative to controls.
Publicat 2019“…Uncorrected statistical maps (yellow), suggested involvement of the ipsilateral hemisphere as well, and a role for the hippocampus.…”
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28084
Efficient Atomistic Simulation of Pathways and Calculation of Rate Constants for a Protein–Peptide Binding Process: Application to the MDM2 Protein and an Intrinsically Disordered...
Publicat 2016“…Many of these pathways involve the anchoring of p53 residue F19 into the MDM2 binding cleft when forming the metastable encounter complex, indicating that F19 may be a kinetically important residue. …”
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28085
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28086
Cocrystals of Caffeine and Hydroxybenzoic Acids Composed of Multiple Supramolecular Heterosynthons: Screening via Solution-Mediated Phase Transformation and Structural Characteriza...
Publicat 2009“…Caffeine, a pharmaceutical model compound, generally forms cocrystals with carboxylic acids that involve an O−H···N hydrogen bond between the carboxylic acid group of the acid and the caffeine imidazole moiety. …”
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28087
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28088
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28089
Indirect Effects Modulating the Interaction between DNA and a Cytotoxic Bisnaphthalimide Reveal a Two-Step Binding Process
Publicat 2009“…The sequence-specific structural and dynamic properties of double-helical DNA play important roles in many biological processes involving DNA recognition. Using a combination of NMR spectroscopy, surface plasmon resonance, and UV thermal denaturation experiments, we have investigated how sequences not making direct contact with the drug modulate the interaction between the cytotoxic agent elinafide and its preferred bisintercalation sites on double-helical DNA. …”
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28090
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28091
Indirect Effects Modulating the Interaction between DNA and a Cytotoxic Bisnaphthalimide Reveal a Two-Step Binding Process
Publicat 2009“…The sequence-specific structural and dynamic properties of double-helical DNA play important roles in many biological processes involving DNA recognition. Using a combination of NMR spectroscopy, surface plasmon resonance, and UV thermal denaturation experiments, we have investigated how sequences not making direct contact with the drug modulate the interaction between the cytotoxic agent elinafide and its preferred bisintercalation sites on double-helical DNA. …”
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28092
Image1_Variable effects of omaveloxolone (RTA408) on primary fibroblasts with mitochondrial defects.TIF
Publicat 2022“…It is currently being tested in medical trials for Friedrich ataxia, a genetic, multi-organ disease involving mitochondrial dysfunction. Thus, omaveloxolone could potentially be beneficial for additional disorders involving mitochondrial dysfunction. …”
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28093
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28094
Indirect Effects Modulating the Interaction between DNA and a Cytotoxic Bisnaphthalimide Reveal a Two-Step Binding Process
Publicat 2009“…The sequence-specific structural and dynamic properties of double-helical DNA play important roles in many biological processes involving DNA recognition. Using a combination of NMR spectroscopy, surface plasmon resonance, and UV thermal denaturation experiments, we have investigated how sequences not making direct contact with the drug modulate the interaction between the cytotoxic agent elinafide and its preferred bisintercalation sites on double-helical DNA. …”
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28095
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer’s Disease Peptide Aβ(1-42)
Publicat 2020“…Our results confirm that uptake of Aβ(1-42) is clathrin- and dynamin-independent and point to the involvement of a new and distinct clathrin-independent endocytic mechanism which is similar to uptake via CLICs or macropinocytosis but that also appear to involve yet uncharacterized molecular players.…”
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28096
Indirect Effects Modulating the Interaction between DNA and a Cytotoxic Bisnaphthalimide Reveal a Two-Step Binding Process
Publicat 2009“…The sequence-specific structural and dynamic properties of double-helical DNA play important roles in many biological processes involving DNA recognition. Using a combination of NMR spectroscopy, surface plasmon resonance, and UV thermal denaturation experiments, we have investigated how sequences not making direct contact with the drug modulate the interaction between the cytotoxic agent elinafide and its preferred bisintercalation sites on double-helical DNA. …”
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28097
Annotated dataset for deep-learning-based bacterial colony detection
Publicat 2023“…Methodologically, this can be followed by culture procedures, which mostly involve determining the number of bacterial colony-forming units on the solid culture media that are visible to the naked eye. …”
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28098
PEGylation Potentiates the Effectiveness of an Antagonistic Peptide That Targets the EphB4 Receptor with Nanomolar Affinity
Publicat 2011“…Therefore, PEGylated TNYL-RAW may be useful for inhibiting pathological forms of angiogenesis through a novel mechanism involving disruption of EphB4-ephrin-B2 interactions between endothelial cells and supporting perivascular mesenchymal cells. …”
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28099
DataSheet1_Prohibitin modulates periodontium differentiation in mice development.docx
Publicat 2024“…</p><p>Discussion: The region-specific localization of PHB in the margin where alveolar bone forms suggests its involvement in alveolar bone formation and the differentiation of the periodontal ligament. …”
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28100
Diffusion network examples.
Publicat 2017“…<p>The network visualization in (a) shows that rumors involve a larger fraction of singletons and smaller communities, resulting in a sporadic diffusion pattern. …”