The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition. (1SNG) per SP Bottomley (2569612)

“…An undesirable result of this conformational flexibility is that most inhibitory serpins are heat sensitive, forming inactive polymers at elevated temperatures. …”

Image_1_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf per Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Nucleophilic Degradation of a β-Diketiminato Ancillary by a Transient Scandium Hydride Intermediate per Korey D. Conroy (2339362)

“…The reactions involving LiAlH₄, along with labeling studies, helped to clarify the fragmentation pathway and account for the observed products.…”

Image_2_Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance.pdf per Isabel M. García-Guillén (10147727)

“…The interactome analysis within each IPN domain yielded specific networks that mainly involve members of the ephrin/Eph and Cadherin families, transcription factors and molecules related to synaptic neurotransmission. …”

Gold-Catalyzed Intramolecular Allylic Amination of 2-Tosylaminophenylprop-1-en-3-ols. A Concise Synthesis of (±)-Angustureine per Prasath Kothandaraman (2047204)

“…The mechanism is suggested to involve activation of the alcohol substrate by the AuCl₃/AgSbF₆ catalyst. …”

Data_Sheet_1_Hostile, Benevolent, Implicit: How Different Shades of Sexism Impact Gendered Policy Attitudes.docx per Claire Gothreau (12993501)

“…The current study examines the impact of various manifestations of sexism on attitudes regarding policies and public opinion issues that involve gender equality or have gendered implications. …”

Liquid–Liquid Phase Separation Induced by Vapor Transfer in Evaporative Binary Sessile Droplets per Ahmed M. Othman (8899406)

“…The findings of this work enhance our understanding of a coupled fundamental process involving the evaporation of multicomponent mixtures, wetting, and phase separation.…”

Synthesis and Characterization of a (−)-Epicatechin and Barbituric Acid Cocrystal: Single-Crystal X‑ray Diffraction and Vibrational Spectroscopic Studies per Iwona Budziak-Wieczorek (10309695)

“…The application of Raman spectroscopy confirmed the involvement of the CO group in the formation of hydrogen bonds between the (−)-epicatechin and barbituric acid molecules. …”

Supplementary Material for: ISPAD Clinical Practice Consensus Guidelines 2024: Diabetes Technologies: Insulin Delivery per Biester T. (20406074)

“…Additional details on AID incorporating data from clinical trials complemented by real-world evidence. 2.Additional focus and details that delineate potential benefits of these systems with new data for youth of all ages, from preschoolers to young adults 3.New data regarding insulin pump therapy that does not involve AID (non-AID) 4.An emphasis on approaches to optimize outcomes for all forms of insulin delivery devices, including insulin pump therapy as well as behavioral, psychosocial, and educational considerations for optimizing the daily use of these devices. 5.A summary of the growing evidence of the technology benefits beyond glycemic outcomes including person-reported outcomes and experience measures and impacts on the quality of life of youth and their caregivers.…”

Synovial sarcoma: case report per Isabella Lima Arrais RIBEIRO (4697353)

“…The Computed Tomography scan showed a hypodense area with diffuse growth and no involvement of the facial bones and the histopathological analysis revealed pleomorphic and oval spindle cells with rounded epithelial cells that formed nests surrounded by fibrous tissue. …”

Analysis of the expression of <i>hns</i> and Sm<i>qnr25</i>, and copy number of the pBS3.25 plasmid upon experimental evolution. per María B. Sánchez (166312)

“…MBS228, MBS229, MBS230 and MBS231 are the evolved strains and MBS25 the original, non-evolved strain. …”

Data_Sheet_3_The relationship between aesthetic preferences of people for ceramic tile design and neural responses: An event-related potential study.ZIP per Jiayin Chen (232428)

“…This study provides relevant information for quantitative aesthetic assessments of environmental design, interior design, and marketing involving ceramic tiles.</p>…”

Covalent Bonding and Atomic-Level Plasticity Increase Adhesion in Silicon–Diamond Nanocontacts per Zachary B. Milne (7507097)

“…First, covalent bonds formed across the interface, where the number of bonds formed was affected by the hydrogen termination of the substrate, the tip roughness, the applied stress, and the stochastic nature of bond formation. …”

Total Syntheses of Amphidinolide T1, T3, T4, and T5 per Christophe Aïssa (2464921)

“…All individual members, except amphidinolide T3 (<b>3</b>), derive from compound <b>39</b> as a common synthetic intermediate which is formed from three building blocks of similar size and complexity. …”

Data independent acquisition mass spectrometry of irradiated mouse lung endothelial cells reveals a STAT-associated inflammatory response per Jos Philipp (4436029)

“…</p> <p><b>Conclusions:</b> These data suggest the involvement of JAK/STAT and cGas/STING pathways in the genesis of radiation-induced lung inflammation. …”

A New Mode of Operation of Pd-NHC Systems Studied in a Catalytic Mizoroki–Heck Reaction per Alexander V. Astakhov (1450873)

“…Metal complexes bearing N-heterocyclic carbene (NHC) ligands are typically considered the system of choice for homogeneous catalysis with well-defined molecular active species due to their stable metal–ligand framework. A detailed study involving 19 different Pd-NHC complexes with imidazolium, benzimidazolium, and triazolium ligands has been carried out in the present work and revealed a new mode of operation of metal-NHC systems. …”

Lewis Acid Catalyzed Three-Component Hetero-Diels−Alder (Povarov) Reaction of <i>N</i>-Arylimines with Strained Norbornene-Derived Dienophiles per Chris D. Smith (2096089)

“…These observations may be rationalized by two competing mechanistic models, involving either a concerted asynchronous [4 + 2]-like mechanism or a stepwise mechanism.…”

Data_Sheet_4_The relationship between aesthetic preferences of people for ceramic tile design and neural responses: An event-related potential study.ZIP per Jiayin Chen (232428)

“…This study provides relevant information for quantitative aesthetic assessments of environmental design, interior design, and marketing involving ceramic tiles.</p>…”

Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsi... per Pablo Pulido (2185855)

“…<div><p>The lifespan and activity of proteins depend on protein quality control systems formed by chaperones and proteases that ensure correct protein folding and prevent the formation of toxic aggregates. …”

Assembly of Heteroleptic Copper Complexes with Silver Salts: From Discrete Trinuclear Complexes to Infinite Networks per Dmitry Pogozhev (2246500)

“…The X-ray crystal structures of these complexes revealed that, albeit no particular association mode is observed for the acac capping ligand, one-dimensional networks are formed with the acacCN capping ligand. Whereas the imidazole peripheral ligand is coordinated to the copper center of a neighboring complex in the structure of (acacCN)Cu(dpm-imid), such an interaction is absent for the pyrazole appended derivative, (acacCN)Cu(dpm-pz), leading to an association mode involving the peripheral nitrile group of the acacCN ligand. …”