Design of Co-crystals/Salts of Aminopyrimidines and Carboxylic Acids through Recurrently Occurring Synthons por Samuel Ebenezer (2068711)

“...Fourteen crystals involving various substituted organic acid molecules and 2-amino-4,6-dimethylpyrimidine (MP)/2-amino-4,6-dimethoxypyrimidine (MOP) were prepared and characterized by using single crystal X-ray diffraction. ...”

Increased Axonal Ribosome Numbers Is an Early Event in the Pathogenesis of Amyotrophic Lateral Sclerosis por Mark H. G. Verheijen (517090)

“...Interestingly, in familial forms of ALS, Schwann cells have been proposed to slow disease progression. ...”

LASSO–penalized clusterwise linear regression modelling: a two–step approach por Roberto Di Mari (9564435)

“...Second, the computations may sometimes involve approximate schemes. Third, variable selection is usually time consuming, due to a complex calibration of the penalty term, possibly requiring several multiple evaluations of an estimator for each plausible value of the tuning parameter(s). ...”

Analysis of the Transcriptomes Downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch Signaling Pathways in <em>Drosophila melanogaster</em> por Landry E. Nfonsam (140247)

“...The <em>Drosophila melanogaster</em> Pax6 homolog Eyeless forms a complex, incompletely understood regulatory network with the Hedgehog, Decapentaplegic and Notch signaling pathways to control eye-specific gene expression. ...”

Lewis Acid-Mediated Reactions of 1-Cyclopropyl-2-arylethanone Derivatives with Allenic Ester, Ethyl Acetoacetate, and Methyl Acrylate por Min Shi (141075)

“...Moreover, by using methyl acrylate to replace allenic ester, the corresponding 7-aryl-3,5,6,7-tetrahydro-2<i>H</i>-benzofuran-4-one and 5-aryl-3,5,6,7-tetrahydro-2<i>H</i>-benzofuran-4-one can be formed in moderate to high yields in the presence of Bi(OTf)₂Cl. ...”

Table_4_Genome-wide identification, characterization, and evolutionary analysis of the barley TALE gene family and its expression profiles in response to exogenous hormones.xls por Tian-jiang Liao (18890476)

“...Expression pattern analyses reveal the potential involvement of most HvTALE genes in responses to exogenous hormones. ...”

Table1_Case report: marfan syndrome (MFS) mimicking cutaneous vasculitis.xlsx por Fiona Price-Kuehne (4281358)

“...Diagnosis of MFS was made via genetic testing of a saliva sample alone using a next-generation sequencing (NGS) targeted gene panel designed to screen for monogenic forms of vasculitis and noninflammatory vasculopathic mimics. ...”

The Bilaterian Head Patterning Gene <em>six3/6</em> Controls Aboral Domain Development in a Cnidarian por Chiara Sinigaglia (334666)

“...Our functional and gene expression data suggest that the head-forming region of bilaterians is derived from the aboral domain of the cnidarian-bilaterian ancestor....”

Real-Time Multistep Asymmetrical Disassembly of Nucleosomes and Chromatosomes Visualized by High-Speed Atomic Force Microscopy por Bibiana Onoa (595317)

“...Our results show that nucleosome disassembly is a sequential process involving asymmetrical stepwise dimer ejection events. ...”

Overview of participant characteristics. por Sally Lindsay (732140)

“...We used a qualitative design involving semi-structured interviews with 19 youth (13 women, 3 non-binary, 3 men), aged 17–30 (mean 23.5 years). ...”

FM – a multiscale, mechanism-driven, dynamic model. por Michael G. Zager (138879)

“...During intact and finasteride treated simulations, the testicular-pituitary axis forms a negative feedback loop between the testes and the brain via LH, T and DHT. ...”

Data_Sheet_1_Insights Into the Resistome of Bovine Clinical Mastitis Microbiome, a Key Factor in Disease Complication.XLSX por M. Nazmul Hoque (8924855)

“...Thus, identifying CM microbiomes, and analyzing their resistomes and genomic potentials will help improve the optimization of therapeutic schemes involving antibiotics and/or metals usage in the prevention and control of bovine CM....”

A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma por André Voigt (4476361)

“...Applying the CSD approach to a published gene-expression data set of cerebral cortex and basal ganglia samples from healthy individuals, we find that the resulting CSD network is enriched in genes associated with cognitive function, signaling pathways involving compounds with well-known roles in the central nervous system, as well as certain neurological diseases. ...”

DataSheet2_Large-Scale Computational Discovery of Binding Motifs in tRNA Fragments.PDF por Lingyu Guan (7498937)

“...Here, we identified such regions of potential interaction on a larger scale, using in vivo formed hybrids of guides and targets in crosslinked chimeric reads in two orientations. ...”

Narrow-Front Loop Migration in a Population of the Common Cuckoo <i>Cuculus canorus</i>, as Revealed by Satellite Telemetry por Mikkel Willemoes (507026)

“...This implies that more sophisticated inherent guiding mechanisms, possibly involving elements of intermediate goal area navigation or more elaborate external cues, are necessary to explain the complex narrow-front migration pattern observed for the cuckoos in this study....”

<b>Collapsin response mediator protein 2 modulates synaptic function by stabilizing the surface expression of phosphorylated AMPA receptor GluA2 subunits</b> por ren (21408623)

“...<p dir="ltr"><a href="" target="_blank">The Collapsin response mediator protein 2 (CRMP2) is one of the most studied members of the CRMPs family, well-documented for its involvement in neurite extension and dendritic spine development. ...”

Public awareness on telepharmacy (N = 387). por Azlina Ahmad (19492996)

“...A cross-sectional study was conducted from Nov 2022 to May 2023, involving 387 Malaysian citizens aged 18 and above. ...”

Oral dyspraxia in self-limited epilepsy with centrotemporal spikes: a comparative study with a control group por Henrique Nicola Santo Antonio BERNARDO (12686578)

“...<div><p>ABSTRACT Background: self-limited epilepsy with centrotemporal spikes, previously considered benign focal childhood epilepsy with centrotemporal spikes show clinical signs of involvement of Rolandic areas, mainly lower area, which may affect the planning and execution of motor sequences. ...”

Simulating the Mammalian Blastocyst - Molecular and Mechanical Interactions Pattern the Embryo por Pawel Krupinski (222305)

“...<div><p>Mammalian embryogenesis is a dynamic process involving gene expression and mechanical forces between proliferating cells. ...”

Video_1_Spindle-Shaped Neurons in the Human Posteromedial (Precuneus) Cortex.MP4 por Francisco Javier Fuentealba-Villarroel (11931005)

“...We discuss the morphology of these cells and those considered VENs in cortical areas forming integrated brain networks for higher-order activities. ...”