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28021
Identification of abnormalities of respiratory complex subunits in DJ-1-deficient cells.
Publicado 2012“…I+III<sub>2</sub>: supercomplex formed of complex I and dimeric complex III. III<sub>2</sub>+IV: supercomplex formed of dimeric complex III and complex IV. …”
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28022
Multicomponent Coupling Cyclization Access to Cinnolines via in Situ Generated Diazene with Arynes, and α‑Bromo Ketones
Publicado 2016“…A transition-metal-free multicomponent coupling cyclization reaction was explored involving arynes, tosylhydrazine, and α-bromo ketones. …”
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28023
C–H Alkylation via Multisite-Proton-Coupled Electron Transfer of an Aliphatic C–H Bond
Publicado 2019“…General approaches to the activation of strong C–H bonds include radical-mediated processes involving highly reactive intermediates, such as heteroatom-centered radicals. …”
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28024
Gene conversion.
Publicado 2013“…A free 3′ end invades the homolog (blue) forming a D-loop and heteroduplex DNA. Non-reciprocal DNA synthesis fills in missing DNA (dashed arrows), forming two Holliday junctions, which may be resolved as either crossovers or noncrossovers, depending on which strands are cut (green and orange arrows). …”
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28025
Example enzyme mechanisms for the reaction AB.
Publicado 2013“…<p>The left panel illustrates the Michaelis-Menten scheme of Equation (8), in which enzyme binds to substrate A, forming a complex C. The product B reversibly dissociates from the complex C, forming unbound enzyme E. …”
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28026
TMEM41B is required for autophagic flux.
Publicado 2019“…The corresponding cell extracts were normalized by total protein, resolved by SDS-PAGE, and analyzed by IB for LC3. I and II indicate the unmodified and lipidated forms of LC3. …”
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28027
Platinum/Scandium-Cocatalyzed Cascade Cyclization and Ring-Opening Reaction of Tertiary Amines with Substituted Salicylaldehydes to Synthesize 3-(Aminoalkyl)coumarins
Publicado 2011“…The synthesis of 3-(aminoalkyl)coumarins starting with a platinum/scandium-cocatalyzed oxidative dehydrogenation of α,β-C(sp<sup>3</sup>)−H bonds of tertiary amines in the presence of ambient oxygen followed by reactions with substituted salicylaldehydes is revealed. The in situ formed enamines reacted with various salicylaldehydes, which resulted in the development of a one-pot synthetic protocol involving aldol reaction, cyclization, and then ring-opening.…”
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28028
orf0489 is required for Aar-induced FFA production and to mitigate Aar toxicity.
Publicado 2013“…Values are the average +/− SD of three independent experiments. <b>B.</b> Colony forming units per OD<sub>750</sub> (CFU/OD<sub>750</sub>) of the indicated strains were determined 48 h post-induction. …”
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28029
A subset of Gcn<sup>-</sup> substitutions of conserved surface-exposed residues in the HisRS domain impair kinase activity but not tRNA binding by purified Gcn2 in vitro.
Publicado 2015“…The Gcn2-tRNA complexes were resolved by electrophoresis through a 1% agarose gel in 1×MOPS buffer (1.5h, 100 V), transferred to a nitrocellulose membrane and visualized by autoradiography. …”
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28030
Data_Sheet_1_Plastid Phylogenomics of Dendroseris (Cichorieae; Asteraceae): Insights Into Structural Organization and Molecular Evolution of an Endemic Lineage From the Juan Fernán...
Publicado 2020“…They demonstrate spectacular and unusual growth forms of rosette trees with extremely variable morphology and occupy wide ecological ranges on the islands. …”
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28031
Oxidative stimuli induce an interaction between TRX1-CS and ATM.
Publicado 2020“…<p>(A) Schematic representation of the reaction mechanism of the TRX1-mediated reduction of a disulfide, in which WT TRX1 forms a transient mixed disulfide with a target that becomes rapidly resolved, resulting in the reduction of the target protein and TRX1 oxidation. …”
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28032
Data used in "A summer heatwave reduced activity, heart rate and autumn body mass in a cold-adapted ungulate"
Publicado 2023“…</p> <h2>Methods of data collection</h2> <h3> Animals and study area</h3> <p>The study involved biologging (see below) 14 adult semi-domesticated reindeer females (Focal animals: Table S1) at the Kutuharju Reindeer Research Facility (Kaamanen, Northern Finland, 69° 8’ N, 26° 59’ E, Figure S1), during June–September 2018. …”
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28033
Data: Snorkel survey
Publicado 2023“…This data is fed in various forms to the BioenergeticsHSC GUI, manual available by Naman et al. (2020). …”
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28034
Intramolecular Anionic Diels−Alder Reactions of 1-Aryl-4-oxahepta-1,6-diyne Systems in DMSO
Publicado 2007“…Base-promoted cycloaddition reactions of 1-aryl- or 1-aryl-7-substituted-4-oxahepta-1,6-diyne systems in DMSO have proven to involve an anionic intramolecular Diels−Alder process taking place even at room temperature in spite of the reaction suffering from temporary disruption of aromaticity. …”
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28035
Intramolecular Anionic Diels−Alder Reactions of 1-Aryl-4-oxahepta-1,6-diyne Systems in DMSO
Publicado 2007“…Base-promoted cycloaddition reactions of 1-aryl- or 1-aryl-7-substituted-4-oxahepta-1,6-diyne systems in DMSO have proven to involve an anionic intramolecular Diels−Alder process taking place even at room temperature in spite of the reaction suffering from temporary disruption of aromaticity. …”
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28036
Formation of IRES-associated complexes in <i>Giardia</i> cell lysates.
Publicado 2009“…IRES-associated complexes were resolved into two peaks (Peaks 1 and 2) by 10–50% linear sucrose density gradient centrifugation. …”
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28037
Model of DSB repair by homologous recombination.
Publicado 2013“…Alternatively, after DNA synthesis the second end is captured, forming a double Holliday junction intermediate. These junctions are resolved by HJ resolvase(s) to generate crossover or non-crossover products, depending on orientation of cleavage of the junctions by resolvase. …”
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28038
Alignment between genetic (left, blue) and physical (right, yellow) maps of <i>P. blakesleeanus</i>.
Publicado 2013“…<p>Nine linkage groups are resolved at LOD score 3 and 12 at LOD score 5: the differences are indicated by dashed lines (these distances not to scale). …”
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28039
Developmental profile of <i>fem</i> mRNA expression.
Publicado 2009“…<p>Fragments corresponding to female (A) and male (B) <i>fem</i> mRNAs were independently amplified by RT-PCR and resolved by agarose gel electrophoresis. The weak ∼1,600 bp fragments observed in reactions devoted to amplify the female-specific fragment correspond to the male mRNAs. …”
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28040
(A) Intrinsic transcript cleavage property of RNAP.
Publicado 2011“…The complexes were incubated for a prolonged time (1–4 hrs) in transcription buffer (pH 7.5), followed by resolving the cleavage products on 20% urea-PAGE. <b>(B)</b> pH-induced transcript-cleavage activity of RNAP. …”