Example enzyme mechanisms for the reaction AB. od Daniel A. Beard (43373)

“…<p>The left panel illustrates the Michaelis-Menten scheme of Equation (8), in which enzyme binds to substrate A, forming a complex C. The product B reversibly dissociates from the complex C, forming unbound enzyme E. …”

Stoichiometric balance of protein copy numbers is measurable and functionally significant in a protein-protein interaction network for yeast endocytosis od David O. Holland (275308)

“…We show here that these correlations in protein copy numbers can extend beyond complex subunits to larger protein-protein interactions networks (PPIN) involving a range of reversible binding interactions. …”

Platinum/Scandium-Cocatalyzed Cascade Cyclization and Ring-Opening Reaction of Tertiary Amines with Substituted Salicylaldehydes to Synthesize 3-(Aminoalkyl)coumarins od Xiao-Feng Xia (1393102)

“…The synthesis of 3-(aminoalkyl)coumarins starting with a platinum/scandium-cocatalyzed oxidative dehydrogenation of α,β-C(sp³)−H bonds of tertiary amines in the presence of ambient oxygen followed by reactions with substituted salicylaldehydes is revealed. The in situ formed enamines reacted with various salicylaldehydes, which resulted in the development of a one-pot synthetic protocol involving aldol reaction, cyclization, and then ring-opening.…”

Data used in "A summer heatwave reduced activity, heart rate and autumn body mass in a cold-adapted ungulate" od Liv Monica Trondrud (13800856)

“…</p> <h2>Methods of data collection</h2> <h3> Animals and study area</h3> <p>The study involved biologging (see below) 14 adult semi-domesticated reindeer females (Focal animals: Table S1) at the Kutuharju Reindeer Research Facility (Kaamanen, Northern Finland, 69° 8’ N, 26° 59’ E, Figure S1), during June–September 2018. …”

Data: Snorkel survey od John McLaren (13131990)

“…This data is fed in various forms to the BioenergeticsHSC GUI, manual available by Naman et al. (2020). …”

Intramolecular Anionic Diels−Alder Reactions of 1-Aryl-4-oxahepta-1,6-diyne Systems in DMSO od Takayuki Kudoh (171894)

“…Base-promoted cycloaddition reactions of 1-aryl- or 1-aryl-7-substituted-4-oxahepta-1,6-diyne systems in DMSO have proven to involve an anionic intramolecular Diels−Alder process taking place even at room temperature in spite of the reaction suffering from temporary disruption of aromaticity. …”

Intramolecular Anionic Diels−Alder Reactions of 1-Aryl-4-oxahepta-1,6-diyne Systems in DMSO od Takayuki Kudoh (171894)

“…Base-promoted cycloaddition reactions of 1-aryl- or 1-aryl-7-substituted-4-oxahepta-1,6-diyne systems in DMSO have proven to involve an anionic intramolecular Diels−Alder process taking place even at room temperature in spite of the reaction suffering from temporary disruption of aromaticity. …”

Nonracemic Allylic Boronates through Enantiotopic-Group-Selective Cross-Coupling of Geminal Bis(boronates) and Vinyl Halides od Bowman Potter (1317984)

“…Mechanistic experiments suggest the operation of a pathway involving outer-sphere stereoinvertive transmetalation.…”

Map showing geographic distribution of all OTUs. od Ron Pinhasi (42876)

“…<p>Dispersal models involving the active migration of people from SW Asia take two basic forms. …”

Detailed Kinetic Monte Carlo Simulations of Graphene-Edge Growth od Russell Whitesides (2309200)

“…The evolving graphene morphology and growth rates seemingly reach “asymptotic” behavior, independent of the initial substrate. …”

Detailed Kinetic Monte Carlo Simulations of Graphene-Edge Growth od Russell Whitesides (2309200)

“…The evolving graphene morphology and growth rates seemingly reach “asymptotic” behavior, independent of the initial substrate. …”

Detailed Kinetic Monte Carlo Simulations of Graphene-Edge Growth od Russell Whitesides (2309200)

“…The evolving graphene morphology and growth rates seemingly reach “asymptotic” behavior, independent of the initial substrate. …”

The Suwgra: A Study of Heritage Preservation and Sustainability od Perla Atiyah (17416554)

“…</p><p dir="ltr">Key concepts: sustainability, preservation of local culture, low impact on the environment, community involvement, natural landscapes, UNESCO sites</p>…”

The effect of bio mass arrangement on nakiwogo landing site, effect on fish and other habitat on lake Victoria.congugated C-N vibrations od Uwayesu Happy Edwards (20797598)

“…Policies encouraging community involvement in clean-up drives or compost production can help foster a sense of ownership within the community. …”

Calculations of p<i>K</i>_a’s and Redox Potentials of Nucleobases with Explicit Waters and Polarizable Continuum Solvation od Bishnu Thapa (1421128)

“…The same numbers of water molecules were hydrogen bonded to the neutral, protonated, and deprotonated nucleobases in their unoxidized and oxidized forms. The improvement in p<i>K</i>_a1 involving neutrals and cations was modest. …”

HOXA2 reduces RCHY1 half-life in a 26S proteasome-dependent way. od Laure Bridoux (481118)

“…Upon prolonged exposition time, western blot with anti-RCHY1 recognizes higher molecular weight bands probably associated to ubiquitinated forms of RCHY1.</p>…”

Functional Connectivity in MRI Is Driven by Spontaneous BOLD Events od Thomas W. Allan (732030)

“…The results show that: 1) spontaneous events in recognised brain networks contribute significantly to network connectivity estimates; 2) these spontaneous events do not necessarily involve whole networks or nodes, but clusters of voxels which act in concert, forming transiently synchronising sub-networks and 3) a task can significantly alter the number of localised spontaneous events that are detected within a single network. …”

Response to different benznidazole doses in animal models of chronic phase Chagas disease: a critical review od Cauê Benito Scarim (5222987)

“…We excluded articles involving acute phase animal models and/or those without BZN treatment. …”

Disulfide Scrambling in Superoxide Dismutase 1 Reduces Its Cytotoxic Effect in Cultured Cells and Promotes Protein Aggregation od Lina Leinartaitė (168595)

“…<div><p>Mutations in the gene coding for superoxide dismutase 1 (SOD1) are associated with familiar forms of the neurodegenerative disease amyotrophic lateral sclerosis (ALS). …”

Collaborative multicenter trials in Latin America: challenges and opportunities in orthopedic and trauma surgery od Vinicius Ynoe de Moraes (5939570)

“…Thus, it seems clear to us that initiatives involving collaborative studies are important for defining and better understanding the patterns of injuries resulting from orthopedic trauma and the forms of treatment. …”