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Mean zipper propensity scores for hexapeptides based on amino acid type and position.
منشور في 2025الموضوعات: -
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Topologically Directed Simulations Reveal the Impact of Geometric Constraints on Knotted Proteins
منشور في 2025"…Here, we introduce a method of <i>topological steering</i> to determine the optimal pathway by which a filament may knot or unknot while subject to a given set of physics. The method involves measuring the knotoid spectrum of a space curve projected onto many surfaces and computing the mean unraveling number of those projections. …"
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Potent Inhibition of Human Betacoronaviruses by a Short Double-Stapled Peptide Mimicking the HR2 Core Region in Viral Spike Protein
منشور في 2025"…Formation of the six-helix bundle involves the evolutionary conservation of key residues in the HR1<sub>core</sub> region. …"