<i>Toxoplasma gondii</i> forms a syncytium with dynamics exchange at the plasma membrane. by Julia von Knoerzer-Suckow (22339771)

Impact of charged residues in a hexapeptide sequence on zipper propensity scores. by Samantha Zink (22120627)

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Performance in amyloid propensity prediction by three fully connected neural network architectures with varying hidden layer sizes, all trained on the same set of ZipperDB data. by Samantha Zink (22120627)

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Structure-informed machine learning-based steric zipper prediction. by Samantha Zink (22120627)

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Charged residues at the zipper interface and the solvent interface have similar effects on the hexapeptide’s overall zipper propensity score. by Samantha Zink (22120627)

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Correlation between Zif and amino acid content for proteins in the S. cerevisiae proteome. Pearsons’s correlation coefficients shown. by Samantha Zink (22120627)

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Correlation between Zif and physical metrics for proteins with known amyloid structures (S1 Table). Pearsons’s correlation coefficients shown. by Samantha Zink (22120627)

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Correlation between Zif and percentage of amino acid type for proteins in the S. cerevisiae proteome. by Samantha Zink (22120627)

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Average zipper propensity score as calculated by Rosetta from 1,563 proline-containing segments. by Samantha Zink (22120627)

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Impact of individual amino acid counts on predicted amyloid propensity scores in hexapeptides. by Samantha Zink (22120627)

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Distribution of ranked Zif and pAD for proteins with solved amyloid fibril structures (see Amyloid Atlas). by Samantha Zink (22120627)

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Metric Calculation. by Samantha Zink (22120627)

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Relationship between amino acid composition and zipper propensity score. by Samantha Zink (22120627)

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Distribution of ranked Zif and pAD for proteins in S. cerevisiae proteome. by Samantha Zink (22120627)

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AlphaFold3 Structure Predictions. by Samantha Zink (22120627)

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Comparison of network architectures for predicting zipper scores. by Samantha Zink (22120627)

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Description and validation of the Structure-Informed Machine Learning Model (a) schematic diagram depicting architecture of the fully-connected neural network (b) The decay of loss... by Samantha Zink (22120627)

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Mean zipper propensity scores for hexapeptides based on amino acid type and position. by Samantha Zink (22120627)

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a) Score distribution for hexapeptides present in Amyloid Atlas. The distribution shape resembles that of all hexapeptides, with similar means. Black line represents the probabilit... by Samantha Zink (22120627)

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Score distribution histograms for zipper data subsets. by Samantha Zink (22120627)

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