Cartoon representation of p53_human (A, B) and of p53_worm structures (C). ‌ Bruno Pagano (466812)

“…<p>Cartoon representation of (A) starting and (B) average final structures of p53_human, highlighting the formation of H-bonds involving Gln144, Trp146 and Asp228 residues (shown as licorice). …”

Diastereo- and Enantioselective Synthesis of Homoallylic Amines Bearing Quaternary Carbon Centers ‌ Jacob C. Green (4061164)

“…Transformations are promoted by a readily prepared (phosphoramidite)–Cu complex and involve bench-stable γ,γ-disubstituted allyldiborons and benzyl imines; products are obtained in up to 82% yield, >20:1 dr, and >99:1 er. …”

Table_1_Established and Emerging Treatments of Skin GvHD.pdf ‌ Cornelia S. Link-Rachner (12031634)

“…This has translated into the approval of several new agents for the treatment of both forms of GvHD. This review summarizes the most recent advances in underlying pathomechanisms, clinical trials and newly approved agents for GvHD, with a special focus on skin involvement.…”

Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI₂–H₂O ‌ Dixit Parmar (2059843)

“…The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl.…”

A Tunable Route for the Synthesis of Azomethine Imines and β‑Aminocarbonyl Compounds from Alkenes ‌ Christian Clavette (1968556)

“…A thermal, concerted alkene aminocarbonylation pathway involving an imino-isocyanate intermediate is proposed and supported by DFT calculations. …”

1,4-Hydroboration Reactions of Electron-Poor Aromatic Rings by N‑Heterocyclic Carbene Boranes ‌ Wen Dai (1607932)

“…When regioisomers are possible, the more crowded (doubly ortho-substituted) product is formed preferably or exclusively. The mechanism may involve oxidation of the NHC-borane to an NHC-boryl radical, reduction of the electron-poor aromatic ring to a radical anion, coupling of the radical and the radical anion to give a cyclohexadienyl anion, and finally regioselective protonation.…”

Hepatic neuroendocrine neoplasm: imaging patterns ‌ Abdallah de Paula Houat (10379710)

“…However, primary hepatic involvement is quite rare. Hepatic NENs can have a variety of radiological presentation forms and can therefore mimic other lesions, making their diagnosis challenging. …”

Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI₂–H₂O ‌ Dixit Parmar (2059843)

“…The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl.…”

Chain Transfer to Solvent in Propene Polymerization with Ti Cp-phosphinimide Catalysts: Evidence for Chain Termination via Ti–C Bond Homolysis ‌ Christian Ehm (1593097)

“…End-group analysis suggests that these are formed after a 2,1-insertion event; density functional theory (DFT) studies support a mechanism involving homolysis of a Ti-<i>sec</i>-alkyl bond. …”

Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI₂–H₂O ‌ Dixit Parmar (2059843)

“…The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl.…”

Congenital Zika syndrome and neuroimaging findings: what do we know so far? ‌ Bruno Niemeyer de Freitas Ribeiro (4647952)

“…<div><p>Abstract Although infection with the Zika virus was first recognized in 1942, it received little attention until 2007, when a true pandemic spread throughout Africa, Asia, and the Americas. Since then, numerous forms of central nervous system involvement have been described, mainly malformations related to congenital infection. …”

Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI₂–H₂O ‌ Dixit Parmar (2059843)

“…The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl.…”

Electrophilic Interaction of 2,3-Allenoates with PhSeCl. An Unexpected Highly Stereoselective Synthesis of 3-Phenylseleno-4-oxo-2(<i>E</i>)-alkenoates ‌ Guofei Chen (2365789)

“…A possible mechanism involving a decomposition of selenate esters was proposed.…”

Supplementary Figure S2. Characterization of the B-cell lymphoma PDX models from B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Perso... ‌ Leo Zhang (13811878)

“…B-C, PDX tumors invaded the mouse spleen and formed splenomegaly. D, Patient abdomen PET/CT images of PT1 and PT5 showed splenomegaly (left panel). …”

A Tunable Route for the Synthesis of Azomethine Imines and β‑Aminocarbonyl Compounds from Alkenes ‌ Christian Clavette (1968556)

“…A thermal, concerted alkene aminocarbonylation pathway involving an imino-isocyanate intermediate is proposed and supported by DFT calculations. …”

Chain Transfer to Solvent in Propene Polymerization with Ti Cp-phosphinimide Catalysts: Evidence for Chain Termination via Ti–C Bond Homolysis ‌ Christian Ehm (1593097)

“…End-group analysis suggests that these are formed after a 2,1-insertion event; density functional theory (DFT) studies support a mechanism involving homolysis of a Ti-<i>sec</i>-alkyl bond. …”

Dissociative Electron Attachment to Anthralin to Model Its Biochemical Reactions ‌ Stanislav A. Pshenichnyuk (1373139)

“…A likely mechanism for the biochemical transformations of anthralin under reductive conditions in vivo is hypothesized on the basis of its DEA properties. The involvement of excited electronic states generated by ultraviolet irradiation of skin is discussed.…”

Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI₂–H₂O ‌ Dixit Parmar (2059843)

“…The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl.…”

1,4-Hydroboration Reactions of Electron-Poor Aromatic Rings by N‑Heterocyclic Carbene Boranes ‌ Wen Dai (1607932)

“…When regioisomers are possible, the more crowded (doubly ortho-substituted) product is formed preferably or exclusively. The mechanism may involve oxidation of the NHC-borane to an NHC-boryl radical, reduction of the electron-poor aromatic ring to a radical anion, coupling of the radical and the radical anion to give a cyclohexadienyl anion, and finally regioselective protonation.…”

1,4-Hydroboration Reactions of Electron-Poor Aromatic Rings by N‑Heterocyclic Carbene Boranes ‌ Wen Dai (1607932)

“…When regioisomers are possible, the more crowded (doubly ortho-substituted) product is formed preferably or exclusively. The mechanism may involve oxidation of the NHC-borane to an NHC-boryl radical, reduction of the electron-poor aromatic ring to a radical anion, coupling of the radical and the radical anion to give a cyclohexadienyl anion, and finally regioselective protonation.…”